Postdoc @Cambridge_Uni | @LabGlover alum | Parthenogenesis | Nuxalk Nation in Canada | she/her | alexislsperling.bsk.social
Joined February 2016
- Tweets 324
- Following 266
- Followers 331
- Likes 2,168
19 Photos and videos
Alexis L Sperling retweeted
8 Sep 2025
šØ Weāre hiring! Oxford Biology is recruiting 3 new Associate Professors in:
š± Plant Sciences
š¦ Animal Behaviour
š¬ Molecular Cell Biology
Join us as we move into our new building with world-class research & teaching facilities.
Vacancies š bit.ly/488CNW3
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Alexis L Sperling retweeted
27 Jun 2025
Expansion of chromosome F heterochromatin in parthenogenetic Drosophila mercatorum biorxiv.org/content/10.1101/ā¦ #biorxiv_evobio
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Alexis L Sperling retweeted
27 Mar 2025
Excited to share our new study revealing the intricate dynamics of pregnancy & postpartum physiology! We analyzed 40M lab tests from 300K pregnancies and 160K women (cross-sectional),
we mapped week-by-week changes starting from preconception to months-long postpartum recovery.
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Alexis L Sperling retweeted
24 Jul 2024
1/9 Glad to share the latest work from @VasadL. A collaborative effort to study the role of the electron transport chain in microglia during development.
nature.com/articles/s42255-0ā¦
rdcu.be/dONoN
@NatMetabolism @ibis_sevilla @unisevilla @CSIC #Microglia #Mitochondria
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Alexis L Sperling retweeted
8 Jul 2024
New paper!
Our stick insects have weird chromosome segregation.
The major centromere protein, CenH3, binds to the autosomes in a monocentric pattern, but in a holocentric pattern on the X.
doi.org/10.1101/2024.06.30.6ā¦
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Alexis L Sperling retweeted
8 Jul 2024
New paper!
Dosage compensation in male reproductive tissues is present only in the early nymphal stages. This is likely due to the establishment of meiotic sex chromosome inactivation during development.
doi.org/10.1101/2024.07.01.6ā¦
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Alexis L Sperling retweeted
17 Apr 2024
Excited to share my first author postdoc paper in Developmental Cell cell.com/developmental-cell/ā¦
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13 Apr 2024
We have our very detailed protocol out that walks through the process of going from an intact fly to an annotated genome assembly.
@DK_Fabian, @erikgarrison, and @LabGlover
13 Apr 2024
Online now: Protocol for preparing Drosophila genomic DNA to create chromosome-level de novo genome assemblies dlvr.it/T5SXFY #protocol #starprotocols #cellpress
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Alexis L Sperling retweeted
14 Nov 2023
āļøCall for Group Leadersāļø
The @IJMonod, a leading center for fundamental interdisciplinary research in biology, is seeking to appoint at least two new group leaders.
ā”ļøijm.fr/?lang=en
Apply before February 16th 2024
Application formā”ļøurlz.fr/ordV
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Alexis L Sperling retweeted
19 Dec 2023
There canāt be a better time to present our recent review/perspective on Gastruloids ā a minimalistic model to study complex developmental metabolism | Emerging Topics in Life Sciences | Portland Press portlandpress.com/emergtopliā¦
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Alexis L Sperling retweeted
5 Dec 2023
!!!New paper alert with @AlexisLSperling !!!
@PlantMethods
Very nice new in situ protocol for plant-parasitic nematodes - un-ambiguous localisation of multiple transcripts within the same parasite.
plantmethods.biomedcentral.cā¦
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28 Nov 2023
I have a new parthenogenesis paper with @LabGlover!
We found that aneuploidy arises during development in natural Drosophila parthenogens and our genetically induced parthenogens
@HeredityJournal
doi.org/10.1038/s41437-023-0ā¦
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27 Sep 2023
Interested in figuring out if an animal is secretly capable of facultative parthenogenesis?
@LabGlover and I made our detailed method available
It works in Drosophila and is worth a try in other animals!
27 Sep 2023
New in: Protocol for screening facultative parthenogenesis in Drosophila #protocol #starprotocols #cellpress dlvr.it/Swh0j5
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Alexis L Sperling retweeted
For an excellent start to the week, why not delve into this excellent new preprint by @AlexisLSperling @Seb_EvdA at @CropSciCentre ? šŖ±
'Whole mount multiplexed visualization of DNA, mRNA, and protein in plant-parasitic nematodes'
biorxiv.org/content/10.1101/ā¦
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Alexis L Sperling retweeted
25 Sep 2023
Wrap your eyeballs around this!
New in situ protocol by @AlexisLSperling
Multiple mRNA, in the same animal, sub-cellular resolution š„². Here is DG SvG effector at the same time.
Preprint:
biorxiv.org/content/10.1101/ā¦
@plantsci @CropSciCentre
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17 Sep 2023
There is a great primer by Jonathon Thomalla and @WolfnerLab for my, @DK_Fabian, @erikgarrison, and @LabGlover's work on #Drosophila #parthenogenesis (doi.org/10.1016/j.cub.2023.0ā¦) out in the last issue of @CurrentBiology!
doi.org/10.1016/j.cub.2023.0ā¦
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Scientists alter the genomes of female fruit flies, allowing them to reproduce without any contribution from a male go.nature.com/458kBr2
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Alexis L Sperling retweeted
31 Jul 2023
š¢#JobAlert Research Assistant position in my lab:
šŖ°š§¬š§Ŗš¬#Drosophila #genetics #devbio #imaging
In beautiful central Cambridge @GeneticsCam @Cambridge_Uni. Funded by @wellcometrust.
More details and to apply: jobs.cam.ac.uk/job/42219/
Deadline 27 August, please RT!
ALT Confocal microscopy image of the posterior of a blastoderm stage Drosophila embryo. DAPI staining in greyscale, wg transcript in green, cad intronic transcript in yellow, opa transcript in magenta, Opa protein in cyan.
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Alexis L Sperling retweeted
31 Jul 2023
Congratulations to first author, @AlexisLSperling, on their recently published paper.
For the first time, scientists have managed to induce virgin birth in fruit flies with the ability to pass this on through the generations šŖ°
š shar.es/afMW9e
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29 Jul 2023
I am excited to share the final version of our work on the genetic basis of virgin birth (parthenogenesis) in fruit flies! It was a joy working with @DK_Fabian @erikgarrison @LabGlover on this understudied phenomenon.
cell.com/current-biology/fulā¦
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29 Jul 2023
Summaries of our paper:
theguardian.com/science/2023ā¦
salon.com/2023/07/28/fly-ingā¦
themessenger.com/tech/scientā¦
nature.com/articles/d41586-0ā¦
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