Does brain aging always mean vessel loss? 🧠We found a surprising hypervascularization, driving cognitive decline & blood-brain barrier damage in aging. 👇🧵biorxiv.org/content/10.64898… Led by @MihailMuc

#WorldCOPDDay “Short of Breath, Think COPD” Helmholtz Munich Drives Research for New Diagnostics, Therapies and Prevention Strategies🫁 👉t1p.de/2sxmc #COPD, the Chronic Obstructive Pulmonary Disease, is a progressive and currently incurable lung disease in which the airways become inflamed and permanently narrowed (obstruction). 💡Worldwide, COPD ranks as the third leading cause of death, with over three million people affected in Germany alone. The challenge: lung damage can occur long before a formal diagnosis is made. Early warning signs like coughing or shortness of breath are often overlooked or underestimated. The World COPD Day 2025 aims to raise awareness of COPD and to highlight the importance of early diagnosis, as the disease is often detected too late. 🌟At #HelmholtzMunich, researchers are driving the development of new diagnostics, therapies, and prevention strategies for COPD. The goal is to understand the immunological foundations of the disease, the impact of nutrition and environmental factors, and how these influences interact with the immune system during the onset and progression of COPD. 👉Check out the Research Highlight “New Hope for Lung Diseases”: t1p.de/lormr @DZG_Forschen @GOLD_COPD @AlionderCPC @LungHealthMUC @StiftungAtemweg #GOLDCOPD2025 #COPDAwareness #LungHealth #ThinkCOPD

We are introducing LipiGo 🤗 A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. by @cerenkimna @kalorintschi biorxiv.org/content/10.1101/… 1/n

BREAKING NEWS The Norwegian Nobel Committee has decided to award the 2025 #NobelPeacePrize to Maria Corina Machado for her tireless work promoting democratic rights for the people of Venezuela and for her struggle to achieve a just and peaceful transition from dictatorship to democracy. #NobelPrize

Learn what’s new in the 2026 GOLD Report! Highlights include a revised chapter on COPD & multimorbidity, updated guidance on exacerbation management, case-finding, treatment algorithms, and vaccinations. Hear directly from the experts on these key updates! November 12–13 | Philadelphia Marriott Downtown. Register today: bit.ly/3FDHJ99 #GOLDCOPD2025

At @HelmholtzMunich we are working toward new therapies for #LungDiseases. Our major goal to investigate why COPD develops and progresses, aiming to translate these insights into better treatments. We have founded @copd_inet, where we connect worldwide to advance COPD research.

An incredible advance in regenerative medicine, reported in @NEJM this week: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | #helpisonthe way! nejm.org/doi/full/10.1056/NE…

Treatable traits! New! We compare inflammation, microbiome, rheology and mucins in asthma, COPD, bronchiectasis, CF and controls. Huge overlap in biology but clear neutrophilic and T2 endotypes in all diseases! Endotypes>disease labels @accpchest journal.chestnet.org/article…

The Resilience of the Human Lungs: Evolution, Smoke, and Disease Lung resilience evolved with fire exposure; studying protection in smokers may unlock new COPD therapies amid modern threats @atscommunity 🔓 Open Access 🔗 tinyurl.com/y4b4sh9f

Incredible work👇MouseMapper AI sounds like a powerful step forward in systems-level biology. Huge potential for translational insight.. BTW. how does lung 🫁 look like in obesity???

Call for papers Deadline 30th June! Submit your best COPD papers to the European Respiratory Journal (IF 21!) ersnet.org/news-and-features…

The Unagi paper is FINALLY out! We present the first application. of a novel AI tool to human pulmonary fibrosis snRNAseq data to identify cellular trajectories & reversak perturbations with proteomics & PCLS validations!! See 🧵 👇🏼 and paper here nature.com/articles/s41551-0…

The new European Respiratory Journal impact factor is 21. Ranked #2 across all resp journals Thank you to the incredible @donsin4 , all authors, our outstanding editors and journal staff ♥️ @ERSpublications @EuroRespSoc IF for selected respiratory journals below

Wrapping up #ATS2025 with @LungAssociation’s CMO Alberto Rizzo and CEO @HaroldWimmer. Grateful to the @LungAssociation for their support of the @atscommunity and @copd_inet. Let’s keep driving science forward—together. #COPD #cureCOPD Link 🔗 hcplive.com/view/lungcast-at…

📜The European Respiratory Journal is calling for new submissions of original research articles, review papers, research letters & viewpoints for a series on COPD in response to the global challenge the disease poses Learn more & submit online by 30 June: bit.ly/44t7SSE

Agree! This 👇 will be a game changer for the early intervention of COPD. #CureCOPD

A beautiful editorial by the great @FrancyPolverino and @meilan_han on why we need to study the airways of #COPD rather than the blood (which is useless in identifying biomarkers for COPD) bit.ly/3EvEwrX

Finally! The Pulmonary Fibrosis Drug Connectome is on #IPFCellAtlas!! If you want to know if a drug is antifibrotic, which cells it targets, or what drugs target a gene , in what cells - go to ipfcellatlas.com/ click on the Connectome tab. Enjoy!! #DataSharing #CurePF4All

“Humans have long coexisted with fire and smoke, and this exposure has significantly influenced our biology—especially our lungs. Cooking food, staying warm, and surviving in primitive shelters all meant constant interaction with smoke. This exposure likely played a role in shaping the lung’s defense systems, suggesting they may be among the most resilient organs in the body, though not indestructible”. We discuss the resilience of human lung in the new Turning the Air Blue @ATSBlueEditor Viewpoint atsjournals.org/doi/abs/10.1…