Stay informed on the forces shaping global health. Holistic Intelligence in Healthcare. Industry Blog. By Anton Baysa, M.D., Ph.D.

Joined July 2024
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Welcome to @AponiaAnalytics 🦉🦉🦉 Curious about how emerging diseases and breakthrough innovations shape tomorrow’s healthcare worldwide? Follow along for the latest news, real-time trends, and unbiased analysis. 🦉📈💊⚕️ Your provider of holistic intelligence in healthcare and biotech. We cover: - #BreakingNews in biotech, medtech, and healthcare. - Health threat reports, emerging #diseases, #outbreaks, #epidemiology. - #MarketAnalysis - Trending companies and #startups. Follow us! @aponia_analytics team 🦉🦉🦉
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$ABVX 🦉 Abivax trades below the 94 pivot, with RSI under 50 and price below 20/50-day averages. Unless 94 breaks, the chart still points toward 74.21 support. boursier.com/actions/actuali…
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$QURE 🦉 Director Jack Kaye received 7,550 RSUs and a 13,980-share option award. He also sold 1,993 shares at $27.06 through an automatic tax-withholding sale tied to vesting. #form_4 uniqure.gcs-web.com/static-f…

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$QURE 🦉 Director Leonard Post received 7,550 RSUs and a 13,980-share option grant. He also sold 1,993 shares at $27.06 in an automatic transaction to cover vesting taxes. #form_4 uniqure.gcs-web.com/static-f…

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$QURE 🦉 uniQure CFO Jeremy Springhorn received 7,550 RSUs and a 13,980-share option grant. He also sold 1,993 shares at $27.06 under a tax-withholding arrangement tied to vesting. #form_4 uniqure.gcs-web.com/static-f…

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$QURE 🦉 uniQure granted CEO David Meek 7,550 RSUs and a 13,980-share option. He also sold 1,993 shares at $27.06 solely to cover taxes tied to vesting. #form_4 uniqure.gcs-web.com/static-f…

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$NTLA 🦉 One CRISPR infusion left 62% of HAE patients attack- and treatment-free for six months. The striking part: no serious adverse events were reported through Week 28 despite permanent gene editing. ir.intelliatx.com/news-relea…
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$INCY 🦉 INCA033989 cut mutCALR burden alongside clinical responses. ET patients reached durable responses in ~2 weeks; MF showed spleen and anemia gains with no dose-limiting toxicities. investor.incyte.com/news-rel…
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$GMAB 🦉 Elderly 1L DLBCL data look split: monotherapy CR 58% with 8 Grade 5 TEAEs, while R-mini-CHOP combo reached 86% CR and 82% 2-year OS in just 28 patients. 👉ml-eu.globenewswire.com/Reso…

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Aponia_Analytics retweeted
Jun 14
Original Article: Lonvoguran Ziclumeran — In Vivo CRISPR Gene Editing in Hereditary Angioedema (phase 3 HAELO trial) nej.md/4gaSsbi #EAACICongress2026 | @EAACI_HQ
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Beyond weight loss: multisystem benefits of #obesity medications thelancet.com/journals/landi… #weightloss #GLP-1 receptor agonists #ENDO2026
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Novo Nordisk's $NVO oral Wegovy pill just saw a big jump in sales, increasing from 134,000 in week 21 to 159,000 in week 22. Fierce Pharma have been tracking the sales of both Wegovy and Foundayo, the rival pill from Eli Lilly $LLY, over time, and based on the early sales figures, it looks like Wegovy continues to be the clear winner at the moment. Plus they also have first mover advantage in the UAE, the UK, where they have recently won approval for the pill, and where sales of oral Wegovy are also expected to be very strong.
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Correspondence: Clinical Long-Read Genome Sequencing for Rare-Disease Diagnostics nej.md/4e03ejh #ESHG2026 | @eshgsociety
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$HIMS (Max Pain $27 | Price $26) — Exp 6/18 Three weeks and three higher pins. $24.50 → $26 → $27. The anchor keeps climbing and price keeps following. Right now $26 is $1 below the new pin with puts fully faded above it. Calls stay quiet until $32, then build without stopping. Everything between $26 and $32 is open air. 🎯 Anchor on the move. $27 is the pin — $1 away. Reclaim it and $32 opens as the first real call level. Where does $HIMS end the week?
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Aponia_Analytics retweeted
3.5% of patients with inflammatory bowel disease (Crohn’s and ulcerative colitis) have autoantibodies against the anti-inflammatory cytokine, IL-10. This is a stunning discovery that shows just how heterogeneous IBD is — and highlights the need for personalized therapy.
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Neutralizing interleukin-10 autoantibodies were found in a subgroup of patients with inflammatory bowel disease and in no controls without IBD. Seropositivity was strongly associated with the IBD HLA-DRB1*01:03 risk allele. Full study results: nej.md/4dXZ3od Science behind the Study: Autoantibodies against Cytokines — From Infection to Inflammation nej.md/4e1EZ4s
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Getting to the root of age-related diseases. By studying a rare accelerated aging genetic disorder, gain-of-function mutations of DNMT3A were found to be causal. DNA hyper-methylation was then linked to stem cells dysfunction and multiple age-related diseases (blood, bone, metabolic). Work in mice and humans. @NatureGenet nature.com/articles/s41588-0…
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$LQDA Hcw catalyst page
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