❗New Open🔓Access Publication 🧪 Nicotinamide riboside treatment enhances stress sensitivity and modulates hematological dynamics in aged mice 👩‍🔬 By Luka Culig & Isabel Beerman (@BeermanHSCaging) et al. This study shows that nicotinamide riboside (NR)—a widely studied NAD⁺ precursor—may ⬆️ stress sensitivity and affect 🩸 blood parameters in aged mice, highlighting the importance of context when considering NR as a longevity intervention. 📖 Read the full paper: ↪️rdcu.be/ezguX #NicotinamideRiboside #NAD #Aging #Stress #Anxiety #Hematology #Geroscience

DNA methylation drives hematopoietic stem cell aging phenotypes after proliferative stress @hagayanay, @BeermanHSCaging and coauthors link.springer.com/article/10… | @GeroScienceAGE

Thrilled to see our hard work on the cover of @CellStemCell! Exploring how cholesterol drives neurotoxicity in PMS iNSCs and showing potential for pharmacological rescue has been an incredible journey. Huge thanks to @Telencephale @Pluchinolab @dalessandrolab & our amazing team.

Fantastic stem cell aging session closing out 2024 CSH mechanisms of aging conference- HSC biology had amazing representation by Danica Chen, Britta Will (and me!). Thanks to Shin Imai, Will Mair, and Meng Wang for all their hard work organizing this great meeting!

Proud of Dr Culig for his excellent presentation at #ARDD2024.

Don't miss the latest #SimplyBlood 🩸 blog post, featuring the ISEH 2024 Janet Rowley Award Winner, Dr. Robert Signer (@SignerLab). Dr. Signer shares his career path to becoming a PI, mentorship, and more! Read more on simplyblood.org/

Kudos to all the NIA summer interns for their hard work. Very proud of my high school intern Tasnim for earning a poster presentation award- she was a joy to have in the lab and we wish her the best for her Senior year!

Excited to share this collaborative work led by the amazing Hagai Yanai & Bongsoo Park showing short-term cyclical diet intervention modifies microbiomes and metabolomes with sex-specific, longterm residual effects not directly correlated to caloric intake rdcu.be/dyrX4

Big congratulations to our fantastic Chief, Dr Rafa de Cabo @NIHAging for being awarded the Denham Harman Award at #AGE2023 for his outstanding contributions to the field.

irp.nih.gov/blog/post/2023/0… Thank you @IRPatNIH for highlighting our (Dr Yie Liu’s team and the ESCA at NIA) work published in Geroscience pubmed.ncbi.nlm.nih.gov/3682…. This blog nicely presents our findings of the exciting potential of NAD supplementation for telomere biology disorders

Very excited to share our recent publication showing that restoring BM niche function rejuvenates aged HSCs @NatureComms (rdcu.be/c9EAP)! Congrats to @pradeepvpr, @GusThePolice, @mc_gutty, and the rest of the talented crew!

Few days left to apply for a #postdoc position in my lab. Join us @ImperialImmuno, @imperialcollege London to work on #stemcells #niche in #clonal_hematopoiesis and #leukemia initiation. More details at imperial.ac.uk/Luis-lab/

Congratulations on the culmination of all the hard work that went into this manuscript. Grateful we got to be a part of this project : out online today at Nature Communication doi.org/10.1038/s41467-022-3…

Many thanks to Elisa Laurenti for hosting my @SCICambridge visit after #ISEH2022 @ISEHSociety! So grateful for chance to visit Cambridge for first time in 16 years, where we also met @BeermanHSCaging. I really enjoyed scientific interactions with Elisa, and your great colleagues.

Coming up 12th Sept 22 at 4 pm | Excited to be hosting @BeermanHSCaging for a joint @SCICambridge and @CentreMyelin seminar on the #epigenetics of #ageing (or the #ageing of #epigenetics 😀) in stem cells | Zoom link available in the poster below

Great start to the NIC Technology Session #ISEH2022

Excited to share our group's latest manuscript that describes age-associated blood changes in rats. Using male rats from 3-27 months of age we define inflection points of blood parameters and a model to potentially predict healthy aging doi.org/10.7554/eLife.76808 @eLife