Molecular and Cellular Neuroscience of C. elegans. We love ion channels, CRISPRing genomes, lighting up worms.

Joined January 2013
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Our study revealing the remarkably complex organisation of the worm's sarcolemma is now online! Almost six years of hard work for our magnum opus revealing this entirely unsuspected new case of planar cell polarity in C. elegans muscles. rdcu.be/dKnoN
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Our latest Preprint: More new CryoEM structures of TASK1 and TASK3 @K2pChannels including the G239R disease-causing mutant structure of TASK3 (KCNK9 Imprinting Syndrome/Birk Barel Syndrome) biorxiv.org/content/10.1101/…
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Our study revealing the remarkably complex organisation of the worm's sarcolemma is now online! Almost six years of hard work for our magnum opus revealing this entirely unsuspected new case of planar cell polarity in C. elegans muscles. rdcu.be/dKnoN
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Grateful for all the invaluable feedback and encouragements provided by our colleagues.
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Link to the Nature Communications website : doi.org/10.1038/s41467-024-4…

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I am delighted to share our newest paper. @GarciaPaulineJ found that Setdb1 is absolutely required for muscle tissue regeneration. This by keeping ancient viral elements silenced in muscle stem cells. @EJPRareDiseases @iNeuroMyoGene @AfmPresse
Online now: Setdb1 protects genome integrity in murine muscle stem cells to allow for regenerative myogenesis and inflammation dlvr.it/T7wXZb
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Congratulations to Oliver Hobert for being elected at the National Academy of Sciences; not often that two faculty members from the same departments receive this tremendous honor!
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Please retweet! TWO open position for PhD candidates at my lab and Thomas Boulin's lab @Boulin_Lab, within the framework of the European Training Network: Molecular plasticity of neurons during C. elegans lifespan. for more info- excitingworms.eu/nervspan/in…
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Out today in @NatureComms We mapped the divergence in transcriptional landscapes between the sexes across development. Check out our website for info on your favorite gene weizmann.ac.il/dimorgena/ nature.com/articles/s41467-0…

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26 Apr 2024
#FlashbackFriday! EMBL celebrates its 50th anniversary in 2024 & we are revisiting past impactful moments. In 2001, EMBL’s commitment to important services for its member states was made clear with new genomics and proteomics core facilities. #EMBL50 embl.org/about/info/archive/…
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Free for 2 weeks: Integrating non-mammalian model organisms in the diagnosis of rare genetic diseases in humans go.nature.com/3O6cGn7 #Review by Shinya Yamamoto, @KancaOguz, @mfwangler & Hugo J. Bellen @bcmhouston @BaylorGenetics #RareDiseaseDay2024 #RareDiseaseDay

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Today is #RareDiseaseDay! As part of a collection from @BioMedCentral & @SpringerNature (go.nature.com/3IjIcLM), three of our reviews will be free for 2 weeks! #RareDiseaseDay2024
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Visit us at #tagc24 on stand 427 to talk about #TrakBox, tracking and behaviour monitoring.
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FAR launches an exciting ARID1B-RD drug repurposing project with @aexbrown from @MRC_LMS. Utilizing @aexbrown’s novel high-throughput C. elegans system, we aim to identify promising candidates for treatments. Anticipating results by March. Stay tuned for updates!
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It took 4 years to build this 3D map of the developing human head, the most complex part of our body sciencedirect.com/science/ar… Tissue clearing #Lightsheet #VirtualReality #3D models & More! Congrats to Raphael Blain, E. Shotar G. Couly @Yorick_Gitton et al. video summary 🔊
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I released a first version of a book on data visualization with R & ggplot2. Target audience = wet lab scientists. It's work in progress, so any feedback/suggestions/comments are appreciated!! #DataViz #Rstats joachimgoedhart.github.io/Da…
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Please RT: S Belin is looking for a motivated postdoc to study translational control of nervous system regeneration. #ribosome #regeneration #translation @AgenceRecherche @Inserm @GINeuroGrenoble @CercogUGA @UGrenobleAlpes
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Happy to share this fantastic news for the #CDB_lab 🤩🤟! We've been awarded a #ERCStG to decrypt the dialogs between young neurons and #PediatricCancers of the peripheral nervous system, #neuroblastoma. So proud of my wonderful #KidsCaN team🎗️@CRCL. #CancerNeuroscience @CNRS
🎉 The latest ERC Starting Grant competition results are out! 400 bright minds have been awarded over €628 million to fund ideas at the frontiers of science & scholarship. Find out who, where and why 👉 erc.europa.eu/news-events/ne… 🇪🇺 #EUfunded #FrontierResearch #ERCStG @HorizonEU
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