Our lab develops new therapies for ovarian cancer, focusing on quiescent CSC & the immune tumor microenvironment @MageeWomens @UPMCHillmanCC

Joined November 2021
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Shifting some of our focus to endometrial cancer. authors.elsevier.com/a/1ickg…

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Buckanovich Lab retweeted
Former Damon Runyon Clinical Investigator @BuckanovichLab and his team set out to understand why only some ovarian cancer patients respond favorably to immune checkpoint inhibitors, and found that the answer lay in the tumor microenvironment. Learn more: bit.ly/3uveOg3
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Buckanovich Lab retweeted
What if we could prevent the recurrence of #ovariancancer? Through critical research, Magee-Womens Research Institute investigators like Dr. Ronald Buckanovich are giving women with cancer new hope. #OvarianCancerAwarenessMonth Make a gift today: bit.ly/3BwtoWA
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JCI Insight - Phase I trial of ribociclib with platinum chemotherapy in recurrent ovarian cancer insight.jci.org/articles/vie…

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A very nice clinical trial from Dr. Lan Coffman
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I'm supporting National Ovarian Cancer Coalition! do.nr/n0ptze via @DonorDrive

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Targeting therapeutic resistance and multinucleate giant cells in CCNE1-amplified HR-proficient ovarian cancer aacrjournals.org/mct/article… A potential new therapeutic approach for women with hard to treat CCNE1 amplified tumors.

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authors.elsevier.com/a/1eY3q… Another interesting paper linking metformin therapy and cancer outcomes.

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Updated perspective on the Hallmarks of Cancer: New Dimensions | Cancer Discovery #cancer #cancerresearch #oncology #science cancerdiscovery.aacrjournals…

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Celebrating the holidays with a multi-national potluck-- Yumm!
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Buckanovich Lab retweeted
Very excited to share our latest paper in @ScienceTM co-led with @BcellBruno on the prevalence of intratumoral Tregs expressing NRP1 and their association with poor outcome in cancer patients. Kudos to my grad student Chris Chuckran who led this study! science.org/doi/10.1126/scit…
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Buckanovich Lab retweeted
.@KellyLeonPSU et al. @airdlab demonstrate that DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A. bit.ly/36vfSn1 Part of the Year in Cell Biology: 2021 bit.ly/3rtllGF #CellBio2021
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Buckanovich Lab retweeted
17 Nov 2021
It's important to be aware of the signs & symptoms of #OvarianCancer like bloating, upset stomach, frequent urination, feeling full quickly & pelvic pain. Contact your doctor if these symptoms persist for 2 weeks. Read @Kandigyrl3's full story at tinaswish.org/kandis-draw/
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Buckanovich Lab retweeted
Ask Congress to Increase Funding for Ovarian Cancer Research and Enact FY 2022 Spending Bills! votervoice.net/Shares/BAAAAA… @BasserBRCA @NOCC_National @RivkinCenter @TinasWish @ocrahope

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Super excited about a new study we published today. This work shows CA-MSC are driving tumor immune exclusion and resistance to immune therapy. This study supports a new clinical trial we will launch in the spring! science.org/doi/10.1126/scia…
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Buckanovich Lab retweeted
Congrats to Dr. Lotze for his @sitcancer 2021 lifetime achievement award. @TRCCC1998
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