My lab studies the interplay between cancer metabolism and cell cycle dysregulation. Professor. The Wistar Institute
Joined May 2017
- Tweets 4,574
- Following 2,389
- Followers 4,513
- Likes 16,816
468 Photos and videos
Pinned Tweet
May 2
Our lab is expanding and hiring both a postdoc and staff scientist! We study how metabolism and cell cycle states drive tumor progression, therapy response, and immune interactions. Philly is a great place to live and do research! See more at: airdlab.com.
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Katherine Aird retweeted
Happy to share melPDomiX, a new multi-omics resource for late-stage melanoma. Integrating genomic, transcriptomic, proteomic, and clinical data, we map mutation impacts and identify candidate drivers of tumor biology and therapeutic response.
sciencedirect.com/science/ar…
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Katherine Aird retweeted
Jun 3
Excited to share the second paper from our lab!
We found that intercellular crosstalk in TME amplifies IL-1β signaling to drive chemoresistance in metastatic ovarian cancer.
Should IL-1β pathway antagonists be considered as part of neoadjuvant therapy?
jitc.bmj.com/content/14/6/e0…
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Nature research paper: αKG-mediated carnitine synthesis drives DNA repair via histone acetylation
go.nature.com/4wOc9vv
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Stay informed. #Ovarcome
medicalxpress.com/news/2026-…
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Katherine Aird retweeted
Targeting Metabolic Mechanism Restores Chemotherapy Sensitivity in Ovarian Cancer
The data showed elevated levels of the metabolite αKG improved #DNArepair, and blocking it made #cancercells more sensitive to treatment
@airdlab @TheWistar
#ovariancancer
hubs.li/Q04jnqy_0
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Katherine Aird retweeted
May 29
A New Role for aKG in Promoting Histone Acetylation and DNA Repair - Katherine Aird
@airdlab @mzspectrum @ApoorvaUboveja
oncodaily.com/voices/katheri…
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Katherine Aird retweeted
May 27
Amazing work from the @airdlab showing the importance of aKG for histone acetylation, rather than its more canonical role as a TCA cycle intermediate and cofactor for demethylation reactions! Kudos to all the authors!
May 27
It's time to rewrite reviews-aKG doesn't just regulate demethylation. Work from my lab and @mzspectrum demonstrates a new role for aKG in promoting histone acetylation and DNA repair through regulating carnitine synthesis. Congrats @ApoorvaUboveja!
nature.com/articles/s41586-0…
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May 27
It's time to rewrite reviews-aKG doesn't just regulate demethylation. Work from my lab and @mzspectrum demonstrates a new role for aKG in promoting histone acetylation and DNA repair through regulating carnitine synthesis. Congrats @ApoorvaUboveja!
nature.com/articles/s41586-0…
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May 27
Thank you to so many collaborators and colleagues: @bitlerlabucd @NadineHempel @BioYupi @naveengw @esd5psu and so many not on here: Katy Wellen, Francesmary Modugno, David Long, Chris Bakkenist, Simone Sidoli, and many more!
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May 27
This work could not have been done with support from @theNCI, @AmericanCancer, and The Sandy Rollman Foundation. Also institutional support from @UPMCHillmanCC and @TheWistar.
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Katherine Aird retweeted
Excited to share our new @biorxivpreprint from the @BradyLab led by Santanu Ghosh.
“Mitochondrial copper stabilizes lipoylated TCA cycle proteins to sustain metabolism and proliferation”
biorxiv.org/content/10.64898…
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Katherine Aird retweeted
We sincerely appreciate Sen. Durbin's long-standing commitment and leadership in championing sustained and robust annual funding increases for lifesaving medical research, and AACR is a strong advocate for this legislation.
The AACR strongly supports the passage of Sen. Durbin's American Cures Act, which would establish vital increases in federal investments in biomedical research with annual 5% real growth for the @NIH and other federal agencies. brnw.ch/21x2qWC
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May 2
Our lab is expanding and hiring both a postdoc and staff scientist! We study how metabolism and cell cycle states drive tumor progression, therapy response, and immune interactions. Philly is a great place to live and do research! See more at: airdlab.com.
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May 2
We are well-funded and have a strong track record of publications (including a recently accepted paper in Nature), trainee funding, and supporting the career goals of all lab members. There are also opportunities for co-mentorship!
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We strongly support both the scientific & professional development of all trainees. There are opportunities to expand into new areas for those looking to transition to independence.
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Apr 11
Looking for a postdoc position and attending AACR in San Diego? I'll be there, too, and the lab is actively recruiting! Send me an email with your CV and cover letter, and I’ll follow up if there is a mutual fit. See more about our research at airdlab.com.
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Katherine Aird retweeted
Join us for the 2026 NYAS cancer metabolism meeting March 24th! The poster deadline is quickly approaching! Speakers include @airdlab @bensahralab @JaviGBermudez @MarcusDGon @KanarekNaama @lab_manning Erika Pearce, Josh Rabinowitz, and @SantoshVardhana
5 Dec 2025
Registration is open for Cancer Metabolism & Signaling in the Tumor Microenvironment, happening March 24 in NYC 📢
This symposium brings together experts to explore how metabolism & signaling drive tumor progression. Early bird pricing through 12/31: events.nyas.org/event/cancer…
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Katherine Aird retweeted
Jan 9
Registration is open for the 2026 @NYASciences Cancer Metabolism Meeting!
Speaker line-up is 🔥: @airdlab, @bensahralab, @JaviGBermudez, @MarcusDGon, @KanarekNaama, @Manning_BD, @SantoshVardhana, Erika Pearce, Josh Rabinowitz
Details link below. See you in the BIG 🍎
cc: @lydfinley, @RichPossemato
5 Dec 2025
Registration is open for Cancer Metabolism & Signaling in the Tumor Microenvironment, happening March 24 in NYC 📢
This symposium brings together experts to explore how metabolism & signaling drive tumor progression. Early bird pricing through 12/31: events.nyas.org/event/cancer…
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Katherine Aird retweeted
Jan 7
Interested in stable isotope infusions but daunted by jugular catheter surgery? New from postdoc @Yumi_Kim0201 : our simple tail vein catheter method enables anesthesia-free infusions in awake, freely moving mice. 🧵
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