Joined February 2021
Photos and videos
chloe retweeted
🚨 Episode 6 of #FromBenchtoPodcast is live! 🎙️👩🏻‍🔬 Tune in as @ChloeFishman and I dive into the fascinating world of #PhageTherapy, the importance of #Mentorship, and a touch of #Astrobiology! 🦠👩🏻‍🚀 Don’t miss this exciting conversation @NatureBiotech open.spotify.com/episode/64h…
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chloe retweeted
First, phages helped us to modify bacterial genomes (lambda-red), now bacterial defense related elements- retrons- help to modify phage genomes - so cool. Will be very interesting to use this method- ordering oligs for cloning:)
9 Sep 2024
A new retron-based method from the innovative @seth_shipman lab now allows making multiple mutations in a phage genome in a single, easy process - from point mutations to small insertions and deletions Read the overview by @IlyaOsterman nature.com/articles/s41587-0…
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chloe retweeted
9 Sep 2024
A new retron-based method from the innovative @seth_shipman lab now allows making multiple mutations in a phage genome in a single, easy process - from point mutations to small insertions and deletions Read the overview by @IlyaOsterman nature.com/articles/s41587-0…
Multiplexed editing of phage genomes using retrons, now published at @NatureBiotech with lots of new bells and whistles. @ChloeFishman @katecrawdaddy @BhattaraiKline @Darshini_Poola @thekarenzhang @alex_gonzadel @matromont nature.com/articles/s41587-0…
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chloe retweeted
Multiplexed editing of phage genomes using retrons, now published at @NatureBiotech with lots of new bells and whistles. @ChloeFishman @katecrawdaddy @BhattaraiKline @Darshini_Poola @thekarenzhang @alex_gonzadel @matromont nature.com/articles/s41587-0…

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chloe retweeted
Continuous multiplexed phage genome editing using recombitrons go.nature.com/3yUNYTi
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chloe retweeted
Immense gratitude to Luciano (@MarraffiniLab) for his support, @daltonbanh for his invaluable guidance, and @ChloeFishman for daily laughter and inspiration. Studying bacTIRial ;) immunity with you all has been one of the greatest joys of my life. biorxiv.org/content/10.1101/…
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chloe retweeted
Multiple packaging simulations produced globally different conformations of the packaged genome, suggesting that the packaging process itself gives mature virions individual traits encoded by the topology of its genome.
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chloe retweeted
New preprint! Simultaneous multi-site editing of individual genomes using retron arrays. We're trying to make it easier to make multiple, non-adjacent, precise mutations to a genome without long cycles of editing, isolating , and editing again. biorxiv.org/content/10.1101/…
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chloe retweeted
“The microbes we found in Hawaii could be similar to microbes that once lived on Mars, or even microbes that live there today,” says @ChloeFishman. Fishman is now an RA at Gladstone. Read more about her work prior to joining our team. ⬇️ go.nasa.gov/3my45Qe

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chloe retweeted
Learn more about @NASAExpeditions and how studying life on Earth helps @NASA search for life on Mars: go.nasa.gov/4397plv
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chloe retweeted
While in a Hawaiian lava tube, astrobiologists discovered new species of microorganisms thriving in the extreme environment! Data gathered will inform future missions to Martian lava tubes, locations some suspect life could’ve migrated to after Mars’ surface became inhospitable.
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chloe retweeted
*Preprint Alert* This one’s in a new area for the lab: phage editing! We're using retrons to produce recombineering donors ~inside~ bacterial hosts. A wild-type phage infects the host and an edited phage comes out. biorxiv.org/content/10.1101/…
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chloe retweeted
I’m excited to share our new paper on the fundamental biology of RETRONS. Retrons are incredible molecular machines that produce small fragments of reverse transcribed DNA in bacteria that functions in phage defense. academic.oup.com/nar/advance… @NAR_Open @GladstoneInst @UCSF_BTS
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chloe retweeted
This week, the @NASAGoddard Instrument Field Team (GIFT) is on the Mauna Loa volcano in Hawaii, researching underground caves formed by molten lava, called lava tubes, so we can better understand them on other planets.
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chloe retweeted
We are testing methods to detect those microbes and also defining where in the lava tube is a good place to find them. That way, when we go to Mars we can know how and where to look for microbial life.
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chloe retweeted
Okay out of the tube again. See all that white stuff from the lava tube? It’s full of life. We are here to find out what microbes are there and how they get their energy. From chemicals? Water? Sunlight? For example some bacteria use sulfur to live & reproduce.
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chloe retweeted
What gear do you need to stay safe in a lava tube? We made this handy guide
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chloe retweeted
Okay tube break to post and take a moment to share how cool this lava tube is. CAVE SCIENCE!!!
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chloe retweeted
Day 3 - heading into the lava tube with the Geochemistry team. The team is collecting samples and taking measurements with a few different instruments - all with the goal of figuring out what the rocks in the lava tube are made of. Do they contain life? What kind?
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chloe retweeted
Seismic waves travel through air much more slowly than they travel through rock, so theoretically, if there’s a big space filled with air underground we should be able to tell based on the time and energy of the waves we detect.
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