We study the biology of normal B cells & their cancerous counterparts. Affiliated with @IcahnMountSinai @TischCancer @SinaiImmunol.

Joined June 2020
11 Photos and videos
The Dominguez-Sola Lab retweeted
Every child deserves the chance to survive and thrive. ✨ In honor of National Cancer Survivor Day, support lifesaving childhood cancer research if you believe in our mission: ow.ly/qiH450Z6lWQ Like & retweet to help us raise awareness. #cancersurvivor #togetherforthe5th
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I think that the beauty (if I may) of this study is on the cell models that we built with @PapapetrouMDPhD. These are based on previous work in her lab exphem.org/article/S0301-472… and extremely valuable, it turns out, to understand how MYC works to transform cells.

What happens when MYC signaling is sustained in hematopoietic cells? This study from @PapapetrouMDPhD and @DDSoLab examines how persistent MYC activity blocks differentiation and promotes leukemic transformation. Explore on exphem.org/article/S0301-472…
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More posts to follow here and on Bluesky, where we just started an account in case you’re interested.
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And we are back. Sorry for the radio silence to those that noticed
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The Dominguez-Sola Lab retweeted
What happens when MYC signaling is sustained in hematopoietic cells? This study from @PapapetrouMDPhD and @DDSoLab examines how persistent MYC activity blocks differentiation and promotes leukemic transformation. Explore on exphem.org/article/S0301-472…
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The Dominguez-Sola Lab retweeted
Congrats to David (@DDSoLab), Eirini (@PapapetrouMDPhD), and the team on how persistent MYC rewires epigenetic landscapes and TF networks, revealing sustained deregulation drives MYC-driven leukemic transformation. @ISEHSociety
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The Dominguez-Sola Lab retweeted
Over 600 New Yorkers attended our Virtual Town Hall today to advocate for state-based science funding! We were joined by researchers, patients, institutions, and elected officials.
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Support a New York State Biomedical Institute for a Healthier, More Affordable Future - Sign the Petition! c.org/YZj6QQZshL via @Change
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We are extremely grateful to @StBaldrick especially to Jack's Pack @jackspack10 ,(stbaldricks.org/hero-funds/j…), for their support in our quest to find better treatments for Burkitt Lymphoma.
Your donation dollars are turning hope into work that saves lives. 💚 Nearly $1.2 million in new grants just announced, and you can learn more about what you helped make possible: bit.ly/48b2cwJ
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The Dominguez-Sola Lab retweeted
Dominguez-Sola @DDSoLab highlights work by Yada et al. (bit.ly/46Quz1c) which demonstrates that effective antibody affinity selection in germinal centers relies on the store-operated calcium entry component of the B cell receptor signaling network bit.ly/3Ndxmdd
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The Dominguez-Sola Lab retweeted
A bunch of @StokesNeuro's trainees (from many points in time) put together a list of '10 simple rules for a supportive lab environment', inspired by the example he set. This has been a wonderful moment of reflection for me personally, as I start my own lab direct.mit.edu/jocn/article/…
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The Dominguez-Sola Lab retweeted
Incredibly excited to share our article “Metastatic recurrence in colorectal cancer arises from residual EMP1 cells” published today @Nature. I hope that you like it! A big thank you to all the co-authors for all their hard work! Highlights in the🧵 1/20 nature.com/articles/s41586-0…

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The Dominguez-Sola Lab retweeted
Impactful words by @CarolynBertozzi today on how diversity in her trainees enabled creativity, not playing by the rules, and ultimately the work that built the field of bioorthogonal chemistry. Diverse science leads to better science!
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To those that make good things happen. #SinaiNPAW2022 #PostdocAppreciationWeek

ALT Carmen Applause GIF by Lana Del Rey

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The Dominguez-Sola Lab retweeted
Recruiting for a fully funded post-doc position to join our growing team! Here’s a link to our lab website, dm or email if interested. Join an incredible, collegial environment @MSKcancercenter & SKI immunology in the heart of NYC. Pls RT! mskcc.org/research/ski/labs/…

Interested in immunology/inflammation/genetics? The Gitlin Lab @MSKCancerCenter is looking to grow and recruit a post-doc! Great opportunity to dissect new pathways controlling the inflammatory response at both tissue & molecular levels. Email Adgitlin at Stanford dot edu
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The Dominguez-Sola Lab retweeted
21 Jul 2022
Gabriele Varano discusses the mechanisms underlying the selection of FOXO1 mutations in germinal-center-derived B-cell lymphomas. @ImmunityCP @DDSoLab @IcahnMountSinai @TischCancer @SinaiImmunol. #JRNLclub jrnlclub.org/research-films/…

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