My review of Bruce Ratner's book "Early Detection", it details the profound impact of #cancer screening tests, like the PAP smear, which almost eliminated mortality from cervical cancer - what if we can do that for more cancers ? linkedin.com/posts/proximity…?

Ian Chalmers quote: “The scandalous failure of science to cumulate evidence scientifically.” and the lack evidence about invasive childbirth (clip)

Another major advance vs cancer! @ASCO #ASCO26 Personalized neoantigen mRNA vaccine 5 year follow-up vs metastatic melanoma reduced recurrence and death by 49% (on top of Keytruda) ascopubs.org/doi/10.1200/JCO…

Another major cancer treatment advance with a personalized mRNA vaccine for melanoma, on top of immune therapy, >70% survival! This fully mobilizes the immune system to destroy the tumor. In fact, it could potentially be applied to most cancers that have specific mutations!

Standing ovation for @RevolutionBio after presenting their data from #KRAS inhibitor in #pancreatic cancer - the hardest to treat and the toughest target - just wow @DrSamuelBHume congratulations

🧠 SCIENTISTS MAY HAVE FOUND A SURPRISING WAY TO REVERSE MEMORY LOSS What if one tiny element already found in the brain could help fight Alzheimer's disease? Researchers discovered that restoring natural lithium levels in the brain reversed memory loss and improved brain function in experimental studies. The findings suggest that a shortage of lithium may play a role in Alzheimer's, opening a new path for future treatments. It's still early research, but the results are giving scientists fresh hope that memory loss may not always be permanent. Source:
University of São Paulo. Replenishing natural brain lithium levels reverses memory loss associated with Alzheimer's disease.

Presented at #ASCO26: Among patients with previously treated metastatic pancreatic ductal adenocarcinoma, the RAS(ON) inhibitor daraxonrasib led to significantly longer overall survival and progression-free survival than chemotherapy. Full phase 3 RASolute 302 trial results: nej.md/4nWaxvM @ASCO

Vitamin D analog improves #pancreatic #cancer survival

The story of the “undruggable” #KRAS

The immune system in centenarians is remarkably youthful, far less prone to inflammaging @NatRevImmunol nature.com/articles/s41577-0…

David Sinclair that is very interesting - always thought that there was a link to infectious agent but had not guessed gum bacteria #alzheimer

Uplifting story thank you Chaz for sharing #ovarian #cancer

Addiction to short-form videos reduces brain activity in the frontal lobe weakening the ability to focus.

More #AI in #HealthcareAI @Nature cytology which is basically looking for abnormal cell under a microscope

Our immune system plays a critical role in all diseases…and now also in aging #Longivity

Great news of additional benefits from the Shingles #vaccine @EricTopol

Your body has a master clock hidden deep in the brain, and it quietly controls almost everything you feel during the day. This chart shows what that clock is actually doing, and why your sleep, hunger, hormones, energy, and mood follow the same 24-hour rhythm every single day. Here’s the simple breakdown: ⏰ The “master clock” lives in the "SCN" (as its abbreviated) Located in the hypothalamus, it takes in light from your eyes and uses it to reset your entire system. • Light in the morning tells your brain: wake up, raise cortisol, increase alertness. • Darkness at night flips the switch: make melatonin, lower body temperature, prepare for sleep. 🌙 Melatonin rises only when the SCN says it’s dark The pineal gland releases melatonin to start the sleep process. If light hits your eyes at night (phones, TVs, bright LEDs), that signal can shut off or slow down. 😴 Serotonin and melatonin are linked During the day, serotonin helps regulate mood and alertness. At night, the system converts part of that serotonin into melatonin to drive sleep timing. 🧠 Your organs follow the brain’s schedule Every major organ has its own “clock genes,” and they all sync to the SCN. That’s why timing matters: Daytime: • Muscle: glycolytic metabolism and strength performance peak • Liver: glycogen and cholesterol synthesis • Pancreas: insulin secretion • Fat: lipogenesis and adiponectin production Nighttime: • Muscle: oxidative metabolism and repair • Liver: gluconeogenesis and mitochondrial biogenesis • Pancreas: glucagon secretion • Fat: lipid breakdown and leptin release (signals satiety) In other words: Your biology isn’t the same at 8 AM as it is at 8 PM. 🍽️ Food and activity act as “secondary clocks” Eating late, irregular sleep, shift work, or inconsistent light exposure can confuse these clocks and throw off hormones, metabolism, and mood. This is why: • Morning light improves sleep • Regular mealtimes stabilize metabolism • Late-night eating increases glucose spikes • Consistent sleep strengthens hormone rhythms • Exercise timing can shift circadian signals Your circadian rhythm isn’t just about sleep. It’s a full-body timing system coordinating hormones, temperature, digestion, metabolism, and repair. Get your light, food, and sleep aligned… And the rest of your biology starts working with you instead of against you. Graphic citation: Unknown Research citation: PMID: 11584554

#diagnostic market momentum: record deal-making & major acquisitions: #Abbott $20B acquisition of @ExactSciences, string of successful #IPOs: @TempusAI @BillionToOneInc @GrailBio #Caris, and M&As @Natera - #Foresight Dx exited for #JPM2026 mailchi.mp/genomicexpression…

One sperm donor, 67 clinics, 14 countries, passed along to at least 197 children a cancer-predisposition gene mutation (TP53) and some children have already been affected investigations.news-exchange…

⚠️ BREAKING: ‘Super-Mutated’ Flu Sweeps Britain NHS Declares Early Crisis, Warns of “Worst Winter Ever” as Experts Urge Mask Use Mandatory masks have been imposed in hospitals in London, Lincolnshire, Shropshire, and Oxfordshire amid alarm at infection numbers.

It worked. Stem cells (mesenchymal) given to patients with a large heart attack reduced major adverse events in a randomized trial vs standard care bmj.com/content/391/bmj-2024…