Joined June 2014
Photos and videos
Daniel Temko retweeted
Delighted to share a substantially updated preprint led by @gladyspoon1 where we used single-cell derived phylogenetic trees from 80 AML patients to show that pre-leukamic evolution is driven by pervasive positive selection biorxiv.org/content/10.1101/…
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So what is probability anyway? Does anyone have an answer satisfied with? Put another way: what does it mean to say there is a 50 percent chance of a coin coming up heads?
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@sp_monte_carlo any thoughts?
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Daniel Temko retweeted
Check out this comprehensive, large-scale, multiplatform, multiomics study recently published in @CellReports on new heterogeneity and transcriptional drivers of #TripleNegativeBreastCancer. #TNBC #BreastCancer @LabPolyak @DanielTemko @ANewShree @nellage #MylesBrown
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Daniel Temko retweeted
How accurate is #histone #inheritance? @Architex_97 & @shaon_chak propose a new model which suggests that the accuracy might be lesser than currently believed. The pre-print of the study is now available on @biorxivpreprint: biorxiv.org/content/10.1101/…
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Daniel Temko retweeted
Noted and will incorporate into 3rd edition @HastieTrevor @robtibshirani @gareth_m_james
Really enjoying James, @daniela_witten, Hastie and Tibshirani's ISLR. I have a modest proposal to improve Figure 7.1, though. #rstats #LePetitPrince
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Daniel Temko retweeted
My Computational Radiation Biology and Oncology Lab @RadNetCRUKCoL @UCLmedphys @uclcancer will soon advertise for a postdoc to work on mathematical/statistical modelling to optimise drug-radiation combination therapy schedules. DM me to discuss. Please RT. #mathonco #radonc
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Daniel Temko retweeted
Correlation Vs. Causation
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Daniel Temko retweeted
We developed an experiment to increase the scale of QTL mapping so that we may observe how 'low effect' variants play a role in determining phenotypes. 1/4
Barcoded bulk QTL mapping reveals highly polygenic and epistatic architecture of complex traits in yeast biorxiv.org/cgi/content/shor… #biorxiv_genetic
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Daniel Temko retweeted
Interested in cancer evolution, big sets of multi-omic data, and mathematical models to make sense of it all? Then we may have just the #postdoc for you. 3 open positions in our central London lab @QMBCI @CRUKCOLcentre funded by #wellcome & @turinginst webapps2.is.qmul.ac.uk/jobs/…
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Daniel Temko retweeted
Excited for my move to @bciqmul to establish my own group on theoretical somatic evolution in October. Post Doc and PhD position available. If you want to work on somatic evolution with great colleagues at the Barts in Central London, please get in touch benjaminwerner.org

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Daniel Temko retweeted
Why does everyone suddenly seem to hate parsnips so much? People obviously aren't cooking them properly
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Daniel Temko retweeted
Why are cousins more similar than mother-daughters in cancer cells? Combining lineage tracking and theory, our work with the Lahav and Paek labs suggests #circadian control of cell division & death (after chemotherapy) behind this surprising phenomenon. go.nature.com/2SVyGmi

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Daniel Temko retweeted
Lovely Fall day at OHSU for the 2018 Early Detection of Cancer conf! They’re serving Stumptown coffee-come see A9!
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Daniel Temko retweeted
The genomic and evolutionary landscape of colorectal adenomas and cancers contrasted using WGS mseq. Some evidence of positive selection in adenomas & cancers occupy fitness peak. Punctuated CNA evolution in cancers. Out at last! Fantastic work @wchcross nature.com/articles/s41559-0…
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Daniel Temko retweeted
Really pleased to see this published. Its our first paper to involve nearly everyone in the group- super team work all! @wchcross @yosoykit @IbrahimAlBakir1 @DrRyanChoi @DanielTemko @marcjwills_ @DrPMartinez @mcdona02 @jansen_marnix @abobbyandrews @DrAilsaHart
10 Jul 2018
Check out our big team effort out in Gut! Evolutionary history of human colitis-associated colorectal cancer, @trevoragraham @DrAilsaHart Dr Simon Leedham #IBD #colitis #cancerevolution gut.bmj.com/content/early/20…
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Daniel Temko retweeted
10 Jul 2018
Check out our big team effort out in Gut! Evolutionary history of human colitis-associated colorectal cancer, @trevoragraham @DrAilsaHart Dr Simon Leedham #IBD #colitis #cancerevolution gut.bmj.com/content/early/20…

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Daniel Temko retweeted
"They really know the score" [sic @DanielTemko] x.com/Vochlea/status/1016636…

10 Jul 2018
Looking for something to feed your England obsession during the long wait until tomorrow evening? Check out this fantastic podcast by our friends at @skycolouredband talking about what makes Three Lions such a great and enduring pop song #ItsComingHome soundcloud.com/skycoloured/t…
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Daniel Temko retweeted
Our paper on quorum sensing in T cells is out in Science !!!science.sciencemag.org/conte…

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