An online resource for researchers studying dermal tissue. Part of the @STEMCELLTech Science News service.
Joined February 2015
- Tweets 7,449
- Following 315
- Followers 954
- Likes 1,027
3,327 Photos and videos
Pinned Tweet
11 Oct 2025
π Stay up to date the easy way!
π Subscribe to Dermal Cell News for free newsletters that feature the latest peer-reviewed publications, reviews, and industry news!
π bit.ly/4kkWMEu
239
Jun 12
Investigators develop a physiologically relevant 3D #melanoma skin model that captures tumorβmicroenvironment interactions and enables more realistic assessment of targeted therapies.
Discover more here:
βΆοΈ bit.ly/4vIf2fU
43
Jun 11
In this study, investigators from the University Hospital Zurich and the University of Zurich
show that NLRP1 inflammasome activation in #keratinocytes drives #psoriasis-like inflammation through an IL-1βIL-36Ξ³ signaling axis, identifying a potential therapeutic target.
π go.nature.com/49VyNsh
64
Jun 10
Researchers show that IDH gain-of-function mutations are linked to immune exclusion and poor response to anti-PD-1 therapy in melanoma, highlighting a potential mechanism of immunotherapy resistance.
bit.ly/4xm4IMq
81
Jun 9
Researchers show that #keratinocytes drive T cell activation in #psoriasis through a RUNX1βGCN5βICOSLG signaling axis, identifying GCN5 inhibition as a potential therapeutic strategy.
π #OpenAccess
Learn more:
π go.nature.com/4xi7LFe
3
4
208
Jun 6
This @CellReports study identifies an extracellular vesicle-antibody axis that constrains #melanoma survival signaling and has biomarker and therapeutic implications.
π #OpenAccess | bit.ly/4e5dF3X
71
Jun 4
Scientists with Dr. @archana_biology investigated the protective role of microRNA-31-5p, which is elevated in #vitiligo lesions, against UV-B-induced DNA damage in #keratinocytes. @CSIR_IND
π€© Read the study in @SciReports: go.nature.com/4ecdxQm
65
Jun 4
The future of early cutaneous squamous cell carcinoma (#CSCC) management lies in response-adapted strategies to tailor the extent of surgery, radiation, and systemic therapy.
π Learn more in this @jitcancer review: bit.ly/4u4WR2R
1
2
302
Jun 2
Researchers with Drs. Jing Jia & Zhengjun Li observe a positive correlation between PHF20 expression and the malignancy and tumor grade of cutaneous squamous cell carcinoma (#cSCC). π go.nature.com/49AQ4Xx
Functional studies suggest that PHF20 promotes #oncogenic phenotypes, including proliferation, invasion, and EMT.
1
51
Jun 1
𧫠This review highlights advances in complex 3D in vitro systems β including full-thickness human skin equivalents, #organoids, and microphysiological platforms. bit.ly/4o0Jwr9
They discuss how these emerging models can be leveraged to interrogate aging biology and support translational research. π£οΈ
1
57
May 29
Scientists demonstrated a novel facet of GSDME as an epigenetic modifier that promotes #melanoma development through the regulation of the centriole biogenesis regulator PLK4.
@cddpress | go.nature.com/4o1dqvq
66
May 28
This Phase I/II, open-label, multicenter study evaluated drug combinations in patients with metastatic #melanoma and cutaneous squamous cell carcinoma.
Learn more! π
@jitcancer | bit.ly/4wSU67l
1
3
313
May 27
Mona Foth and scientists at @UUtah found that both compounds demonstrated potent anti-proliferative activity against NRAS-mutated #melanoma cell lines and robust anti-tumor activity against preclinical melanoma models.
@CR_AACR | bit.ly/4nU1ueH
1
58
May 26
π‘ Researchers at @MoffittNews identified the small MAF family transcription factor MAFG as a critical regulator of MITF activity and melanoma cell state plasticity.
@NatureComms | go.nature.com/4nS5gp2
1
83
May 26
π‘ Check this out!
Chris Ke Bai and researchers at @Cornell showed that H3K9me3 deposition is dynamic during epidermis morphogenesis and essential for lineage diversification.
@NatureComms | go.nature.com/4u1W82x
1
87
May 22
The expression and role of catestatin (CST), a chromogranin A-derived peptide with immunomodulatory and reparative properties in skin injury, led a @UCSanDiego team to examine its connection to #melanoma.
Learn more in their @oncogenejournal study.
π go.nature.com/49K3b8I
1
89
May 21
This @cddpress study determined that lysine-specific histone demethylase 1 (LSD1) expression is upregulated in metastatic #melanoma relative to primary melanoma, which is indicative of a poor prognosis.
π Learn more: go.nature.com/49IFQnQ
95
May 21
Short-term sodium dodecyl sulfate exposure rapidly disrupts human #SkinBarrier integrity through oxidative stress-driven suppression of structural/immune mediators and activation of stress/remodeling pathways, reports a University of Zurich team.
π bit.ly/3RzjKxS
67
May 19
The orchestrated network of skin photoaging. π
The authors discuss the cellular and molecular mechanisms underlying skin photoaging, and details the roles of and reciprocal crosstalk among fibroblasts, keratinocytes, and #melanocytes.
π bit.ly/4nD3RTd
1
66
May 18
Dr. Tanya Shaw and @KingsCollegeLon collaborators investigate the #transcriptional changes that primary #dermal cells isolated from keloid or adjacent non-lesional skin undergo during standard fibroblast culture conditions by scRNA-seq. π§¬
bit.ly/4dc6VSC | @iScience_CP
1
1
56
May 15
Scientists reveal that DUSP1 protects human dermal fibroblasts from UVB-induced photoaging by regulating ferroptosis. βοΈ
π bit.ly/48X3A7A
58