Neuroradiologist | Molecular Medicine | into science and data | via Oxford Med | devsinha.bsky.social

Joined September 2013
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This CT scan is definitely the most traumatic during lockdown I've been shown. Archery accident. Arrow through the heart. Miraculously and thankfully the patient survived. Let's look at all the ways they were lucky:
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Fiscal drag affects all taxpayers, not just pensioners. There's no good reason to treat working-age taxpayers like we're second class.
New: Andy Burnham will leave the triple lock untouched and consider a tax cut for pensioners paying income tax because of the freeze on tax thresholds, known as “fiscal drag”.
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Kier Starmer and his new health secretary making Streeting look like a chump. Imminent leadership competition certainly focussed minds.
Jun 13
At the last moment, ahead of next week’s action, the Government has moved and made a new offer for resident doctors in England. Strikes for 15–19 June have been called off while members vote on a new offer covering jobs, pay and progression. The choice is yours: Vote YES and accept the offer, or vote NO and return to escalated industrial action.
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NHS planning & funding is borked. NHSE are admonishing dept for not doing 400 stroke thrombectomies per yr. A transformative minimally invasive radiology treatment where UK massively lags Europe. NNT<3 Cf NNT in PCI for OMI ~10 Same NHSE refuses to pay for more than 230/yr 🤷‍♂️
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Thanks to UK gov policy after marginal tax rates and student loans that's only: £208 if UG Med or £182 if GEM Quite an attractive rate to purchase an extra 4 days leave in June and respite from NHS working conditions tbf #economicincentives
Later this month, striking will cost F1 doctors nearly £500 in this round alone. 16 rounds of industrial action do not come without a cost. For our lowest paid colleagues, striking is incredibly expensive. Doctors are being asked to absorb significant financial losses in the pursuit of the fantasy of 2008 pay restoration.
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For context bc of general NHS financial crisis my Trust keeps advertising extra annual leave purchases. It would cost me as a consultant doctor £924 (net after taxes) for the same 4 days.
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Devan Sinha retweeted
This, if anything, underplays it. Only Yemen, Zimbabwe, Jamaica, Tajikistan and Syria have seen bigger drops in electricity use per capita since the year 2000.
This should be a wake-up call for the UK… (Note that this is a per-capita chart)
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Genuinely believe GLP1/GIP drugs are a phenomenal medical success story and underutilised or overly restricted by UK/NHS Still think outside of highly specialised paediatric endocrine/obesity clinics I wld not want my kid with unfused growth plates anywhere near them & catabolic
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Devan Sinha retweeted
Having read the @gmcuk Outcomes for Graduates of Medical Schools, I suggest all UK Medical Students sit USA exams, USMLE. There's a serious danger UK Medical Qualifications might not be recognised outside UK - so little emphasis on Medical Knowledge & Expertise. @DrLKVaughan
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This claim is ludicrous for two reasons: 1. The links in the article don't reference the original DH claim (so the Indie may have misreported it) 2. 20k fewer visits is trivial when there are ~20m visits per year.
NHS patient record change will slash A&E visits by 20,000, government says trib.al/0uZsQE9
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Before the war: A) Iran was sanctioned B) Hormuz was open C) Iran didn't have nukes After the war: A) Iran UNsanctioned B) Hormuz open at IRGC discretion C) No nukes but want them more... First Iranian-Persian victory since 1823 Treaty of Erzurum after defeating Ottoman Empire?
🚨 "An Agreement has been largely negotiated, subject to finalization between the United States of America, the Islamic Republic of Iran, and the various other Countries, as listed..." - President Donald J. Trump
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Devan Sinha retweeted
🦔Microsoft canceled its internal Claude Code licenses this week after token-based billing made the cost untenable, even for a company with effectively infinite cloud resources. Uber's CTO sent an internal memo warning the company burned through its entire 2026 AI budget in just four months. American AI software prices have jumped 20% to 37%, and GitHub (owned by Microsoft) is dropping flat-rate plans for usage-based billing across its products. My Take The AI subsidy era is ending in real time. The same company that put $13 billion into OpenAI and built the Azure infrastructure powering most of Anthropic's compute just looked at the bill from a competitor's coding tool and decided it was not worth paying. That is not a productivity failure on Anthropic's end. Token-based pricing is forcing every enterprise customer to confront the actual cost of running these models at scale, and the number turns out to be far higher than the flat-rate experiments suggested. This ties directly to my Gemini Flash post yesterday. Anthropic, OpenAI, and Google all raised effective prices in the last six months. Enterprises that built workflows assuming AI costs would keep falling are now watching annual budgets evaporate in months. Two outcomes look likely from here. Either enterprises scale back AI usage to fit budgets, which slows the revenue ramp the labs need to justify their valuations ahead of IPOs, or the labs cut prices and absorb the losses, which makes the unit economics worse at exactly the wrong moment. Both paths land in the same place, the numbers stop working, and somebody has to take the writedown. Hedgie🤗
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Tremendous result for Phase III Retatrutide (GLP1 GIP Glucagon) 30% weight loss by week 104 in extension/crossover morbidly curious what wld happen if I gave myself a stab as healthy male w/ BMI 20.5, probably hospital admission for malnutrition & parenteral feed by week 10
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China saving the global economy from Trump's Hormuz energy crisis by foregoing 4Mbd of oil demand. = 1/3 of total lost supply after partial SoH bypasses by Saudi & UAE pipelines
China continues to cushion the global oil market, with imports May-to-date plunging significantly below even the depressed levels seen in April. At the current pace, Chinese crude oil imports are set to hit a 10-year low in May. On a four-week average, Chinese crude/condesate imports are running >4 million b/d BELOW pre-war levels.
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Even the new Japanese MAGLEV line is cheaper. 60% faster for 35% lower cost. Oh and 88% tunnel through bloody mountains 2x taller than Ben Nevis too. 🇯🇵 Chūō Shinkansen: $405 mn/km
Ben isn’t exaggerating about the order of magnitude difference. In constant $: 🇬🇧 HS2: $626 mn/km 🇫🇷 LGV to Bordeaux: $43 mn/km 🇮🇹 Brescia–Verona: $63 mn/km 🇰🇷 Suseo line: $89 mn/km. Pricey. But that’s because it’s 87% in tunnel.
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Devan Sinha retweeted
HS2 was a brilliant idea for £10bn, and is a terrible one for £100bn. That’s why getting costs down is the most important thing for Britain to do if it wants infrastructure abundance.
Government now calculates HS2's benefit cost ratio to be 0.3-0.4 The original 2013 business case said there was a ZERO per cent chance the BCR would be below 0.75
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So Ed Miliband would rather help Putin's war machine than give up his 'green' shibboleth
Remember how last Oct the UK said it was going to ban oil products (eg diesel/kerosene) made from oil that originally came from Russia (eg refined in India etc)? Well now, in the face of the current shortage, that sanction has now been canned👇
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So stop borrowing money from the bond market and then we can ignore its views about credit worthiness & inflationary fiscal policies. All it takes is £257 Billion of spending cuts/tax rises a year. Real simple.
UK gilt yields have hit an 18-year high. That's not because the economy collapsed. It's because bond markets fear Labour might elect a slightly more left-wing leader. When financial markets seek to constrain democratic choice, that is not economic discipline. It is political power, exercised without a ballot. cnbc.com/2026/05/13/gilts-st…
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Devan Sinha retweeted
May 13
Among patients with stroke due to medium-vessel occlusion, thrombectomy led to functional independence at 90 days (in 58.6% of patients, vs. 46.6% with medical management) but also to a higher risk of intracranial hemorrhage. Full ORIENTAL-MeVO trial results: nej.md/42z7dNj Editorial: Endovascular Therapy for Medium-Vessel Occlusion Stroke — Narrowing the Target Population nej.md/4d9ALY4
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Devan Sinha retweeted
Was asked to look at my mom’s dog’s brain MRI today. A few thoughts: dog brains are remarkably similar to human brains, just comically tiny. Veterinary MRI uses many of the same sequences we use in humans. Impression: good boy.
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Wow Diane Abbott wants £257 Billion of austerity in a single year (bond issuance HMG needs covered this year for the deficit maturing bonds). Ie what the govt needs to do to tell the bond market to f*ck off. 3X Osborne's austerity regime in 1/6th the time.
Diane Abbott just said, 'If the government is to be completely dominated by the bond market, MPs might as well go home'. She's right, but not for the reasons she thinks...
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