The Didonna Lab aims at understanding the mechanistic connection between aberrant immune responses and neurodegenerative processes in chronic human diseases.
Joined November 2021
- Tweets 246
- Following 695
- Followers 327
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Apr 18
Really excited to share our new work on the neuroprotective role of specific HLA alleles on Parkinson's disease that was published in Neurology N2 @GreenJournal @ECUBrodySOM
neurology.org/doi/10.1212/NX…
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Didonna Lab retweeted
Tomorrow leaders and officials and our construction partners gather for a topping out ceremony for the Brody Center for Medical Education. It's a reminder that we're not just expanding, we're investing. In our best and brightest. In better health outcomes in #ENC.
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Didonna Lab retweeted
Judge Jack Jenkins, youngest son of former ECU Chancellor Leo Jenkins, gave a Brody Auditorium lunchtime talk on his father’s leadership style. One tip that stood out — put in the work. Another, make the choice as leader you know is just and right in your heart.
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Didonna Lab retweeted
Congrats biomedical sciences grad students on your _18_ first-author publications (28 total) this academic year, and particularly award winners Savanna Williams, Drew Theobald, Kathryn Lorbacher and (not pictured) Connor Cribb.
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Nature research paper: Lineage and organ signals sequentially build organ intrinsic nervous systems
go.nature.com/4devih6
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Didonna Lab retweeted
Shared Epitope-Positive HLA Alleles Protect Against Alpha-Synuclein Pathology in a Model of Parkinson Disease hubs.la/Q04f9SWY0
#NeuroTwitter #ParkinsonDisease
ALT Figure 1 HLA-DRB1*04:01 Expression Protects Against Synuclein Spreading In Vivo
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May 8
Proud to see @EastCarolina recognized by the @cure345 Innovation Index as one of the top 303 U.S. institutions advancing biomedical innovation.
wewillcure.com/innovation-in…
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Didonna Lab retweeted
Apr 20
#ECU researchers are driving what’s next. ⏩
More than 60 scholars, innovators and creators were recently honored for their contributions to research, creative activity and innovation.
Learn more ⤵️ bit.ly/4mAd3ao
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Apr 10
I am truly grateful for receiving the Early Career Trendsetter Award. This achievement could have not been possible without the support of Brody, the Department of Anatomy & Cell Biology and all the dedicated people working in the lab.
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Mar 10
Multiple molecular mimics in Epstein Barr Nuclear Antigen-1, and the pathogenesis of multiple sclerosis
pnas.org/doi/full/10.1073/pn…
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Meet our 2026 Brody Brothers Endowment Research Grant recipients! These are primary investigators of deadly cancers, cellular metabolism, parasite-host dynamics and more. Thank you, Brody Family, for your _ongoing_ generous support of these researchers at @ECU.
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20 Dec 2025
Great teamwork for the traditional departmental door decoration contest that resulted in our first second place🎄
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Didonna Lab retweeted
27 Nov 2025
Some archaea—an ancient group of microorganisms—have an entirely novel genetic code, according to a new study in Science. Their genetic code reassigns a DNA “stop” signal to incorporate the rare amino acid pyrrolysine into their proteins.
The findings expand our understanding of how alternative genetic codes evolve and hint at new molecular tools for biotechnology applications. scim.ag/49xnYx3
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13 Nov 2025
Thrilled to see our paper published in @FEBSJournal — We used a novel conditional knockout line to dissect the function of ataxin-1 in the B cell compartment @ECUBrodySOM
febs.onlinelibrary.wiley.com…
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Didonna Lab retweeted
10 Nov 2025
BREAKING NEWS: @Roche have announced their BTK inhibitor, #fenebrutinib, has achieved successful trial results in both relapsing-remitting & primary progressive #MultipleSclerosis. #MS [1/2]
Read more: roche.com/investors/updates/…
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7 Nov 2025
A lab coordinator position is available at ECU Brody School of Medicine to manage the flow cytometry and cell imaging core facilities. If you have hands-on experience in these techniques and you are interested in the position apply here:
ecu.peopleadmin.com/postings…
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31 Oct 2025
Thrilled for Rachael's first official persentation of her project on MS!
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31 Oct 2025
Excited to be part of the Neuroscience Symposium for the Eastern Carolina Chapter of the SfN. Here, John presenting his work on centaurin A1 in MS.
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Didonna Lab retweeted
14 Oct 2025
Thrilled to celebrate😀, Dr. Jill A. Hollenbach
@jillahjillah recipient of the 2025 Bernard Amos Distinguished Scientist Award at #ASHI51! 🏅for her pioneering work in HLA & Immunogenetics. So proud to learn from the best. 🧬✨ #ASHI2025 #HLA #Immunogenetics
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6 Oct 2025
BREAKING NEWS
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”
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