Joined October 2021
- Tweets 76
- Following 250
- Followers 105
- Likes 275
1 Photos and videos
Drew Carson retweeted
8 Jan 2025
The latest Link lab paper is out @BiochemistryACS!: doi.org/10.1021/acs.biochem.… This work, led by Angela Zhu, focuses on the cysimiditides, a new subfamily of #RiPPs. The cysimiditides include a tetracysteine motif that coordinates a zinc ion and a single aspartimide moiety.
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Drew Carson retweeted
11 Dec 2024
Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @DjenetBousbaine led the charge... @Nature 1/55
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Drew Carson retweeted
8 Oct 2024
Emergence of a distinct mechanism of C–N bond formation in #photoenzymes by Felix C. Raps @felix_raps, Ariadna Rivas-Souchet, Chey M. Jones @CheyMJones, and Todd K. Hyster @HysterLab at @PrincetonChem nature.com/articles/s41586-0…
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3 Jun 2024
Excited to be at @BostonBacteria at Boston Univ! Looking forward to some great science #BBM2024 🧫 I’m presenting poster number 104 tomorrow, come say hi!
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Drew Carson retweeted
22 May 2024
Psst. Hey.
Yeah you.
Want to build 100s to 1000s of plasmids (*any sequence* up to ~6000 bp) for about $10 to $40 each?
salislab.net/software/build_…
Try it out ... feedback is welcomed & encouraged :)
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Drew Carson retweeted
18 May 2024
Our chemoenzymatic synthesis of the lasso peptide Microcin J25 is out now in @J_A_C_S! We used flow-SPPS to synthesize several sidechain- and backbone-modified precursor peptides and demonstrated their in vitro transformation. pubs.acs.org/doi/10.1021/jac… @UZH_Chemistry @Hartrampf_Lab
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Drew Carson retweeted
7 May 2024
Our chemical synthesis of PTM-modified MYC peptides and their interactions with the tumor suppressor Bin1 is online @ChemicalScience.
Congratulations @elysetwilliams, @rebeccabev5, @ZerbeOliver, and everyone else involved! 🎉
pubs.rsc.org/en/content/arti…
#MyFirstChemSci
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Drew Carson retweeted
23 Apr 2024
Excited to release our latest work, led by Sebastian Gonzalez La Corte (@sesgonzalez) with Ned Wingreen: doi.org/10.1101/2024.04.18.5…!
Here, we show that polymers unexpectedly sculpt proliferating bacterial colonies into spaghetti-like "cables".🦠🍝
Tweetorial follows! [1/10]
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Drew Carson retweeted
18 Apr 2024
The latest Link lab paper is out @J_A_C_S today led by @bsmchoi: pubs.acs.org/doi/10.1021/jac…. In this work we show that ATP grasp enzymes that usually make esters can also make thioesters.
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Drew Carson retweeted
2 Apr 2024
Identification of a 2-Aminobenzimidazole Scaffold that Potentiates Gram-Positive Selective Antibiotics Against Gram-Negative Bacteria (C. Melander et al.) @MelanderLab onlinelibrary.wiley.com/doi/…
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Drew Carson retweeted
28 Mar 2024
Excited to share the latest Link lab paper on the uptake of lasso peptide antibiotic cloacaenodin into susceptible bacteria. The work was led by @DrewCarson712 in the Link lab and another collab with @ZhongyueY. pubs.acs.org/doi/full/10.102…
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25 Mar 2024
Our new paper is just out now in ACS Chemical Biology! Here we uncover the transport pathway that the antimicrobial lasso peptide cloacaenodin uses to be able to kill susceptible bacteria. This helps explain the narrow-spectrum activity we observe.
pubs.acs.org/doi/10.1021/acs…
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25 Mar 2024
Our lab's work highly suggests that narrow-spectrum antimicrobial lasso peptides (MccJ25, cloacaenodin, ubonodin) evolved their specificities as a result of their hijacking unique, outer membrane proteins (using active transport) to cross the formidable Gram-neg outer membrane.
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25 Mar 2024
Very happy to have this out! Huge thanks to everyone involved in this. A fun collaboration with the Yang lab at Vanderbilt. @ajlinklab @ZhongyueY @EPrinceton @VanderbiltChem @ACSBioMed
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Drew Carson retweeted
20 Mar 2024
Our preprint on “Merging Flow Synthesis and Enzymatic Maturation to Expand the Chemical Space of Lasso Peptides” is now available from @ChemRxiv 🧪🧫. Congratulations to first author Kevin Schiefelbein and everyone else involved 🥳
chemrxiv.org/engage/chemrxiv… @Hartrampf_Lab
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Drew Carson retweeted
14 Mar 2024
Why are some non-antibiotic drugs toxic to bacteria 💊☠️🦠? Do they work like standard #antibiotics (ABX)? Our latest work by @MarianaNoto published @ScienceMagazine addresses this fundamental question (1/n)
science.org/doi/10.1126/scie…
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Drew Carson retweeted
25 Jan 2024
Another exciting new tool to engineer biology from the Jason Chin Lab >>> Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli | Science science.org/doi/10.1126/scie…
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