Lifelong RNA biologist with a lab full of CRISPR pros who are pro-CRISPR and pro-AntiCRISPR @RTI_UMassChan

Joined February 2020
11 Photos and videos
ErikSontheimerLab retweeted
The RTI's Anastasia Khvorova elected to the National Academy of Inventors Fellows Class of 2022! The new class @AcadofInventors is comprised of 169 prolific academic innovators from over 110 research universities and research institutes worldwide: ow.ly/TTy950LWi2k
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ErikSontheimerLab retweeted
We wish #LaskerAward winner Victor R. Ambros a happy birthday! By studying the microscopic worm #Celegans, he discovered that small RNAs are key regulators of gene expression. @UMassChan #modelorganism ow.ly/Ak7150CsW9p
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ErikSontheimerLab retweeted
Proud to be at the top in the heart of New England: UMass Chan Medical School is on The Boston Globe’s 2022 list of the Top Places to Work in Massachusetts because of its collaborative, inclusive culture: bit.ly/3is9O83 #WhyUMassChan #workboston @BostonGlobeMag

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ErikSontheimerLab retweeted
#HAE News: Today at @ACAAI, Intellia presented additional interim results from its ongoing Phase 1/2 study of NTLA-2002, an investigational, in vivo #CRISPR #genomeediting therapy for HAE. Learn more: bit.ly/3NZyH6H
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This news makes my day 👏👏👏
24 Oct 2022
Thank you to the HFSP Nakasone award, this is a great honor. Stoked and humbled to be included in the same list as the amazing scientists who received this award in the past hfsp.org/awardees/hfsp-nakas…
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Huge congratulations to Professor Watts on this richly deserved promotion! 👏👏🥂
24 Oct 2022
Ok, so my amazing group (I presume!) foil-wrapped my entire office, and everything in it, to celebrate my just-announced promotion to professor.
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ErikSontheimerLab retweeted
"Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors" Iyer S et al.... @ESontheimerLab Scot Wolfe liebertpub.com/doi/10.1089/c…
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I’m joining you on that island. As a reviewer, I’ve always found it as helpful as getting clubbed over the head.
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Take it from me: Tomás rocks
MD/PhD student Tomás Rodríguez restarted @UMassChan’s Latino Medical Student Association chapter in 2020. He established the optional Medical Spanish elective in collaboration with students from all three schools. #HispanicHeritageMonth @trodriguezUMMS @UMassMDPhD @UMassChanSOM
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🤜🏻🤛🏻
Replying to @JKeithJoung
As @grunewaju notes in his summary, @ESontheimerLab also published similar findings about split prime editors in @NatureBiotech earlier this year: nature.com/articles/s41587-0…. 7/7
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Great stuff Keith! 👏
Excited that the latest @JoungLab paper describing split #CRISPR prime editors is out online @NatureBiotech today. This work was led by @grunewaju, Bret Miller, @ReganSzalay with co-authors Peter Cabeceiras, Chris Woodilla @elizajaneholtz @Karl_Petri nature.com/articles/s41587-0… 1/7
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Replying to @grunewaju
Please also check out this fantastic @ESontheimerLab paper that was published in NBT recently, describing the "split-PE" discovery (and much more amazing stuff!) nature.com/articles/s41587-0…
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Great work, Julian, congrats! (And from your previously tweeted photo: nice new digs in Munich 😉)
Boston RT party!🧬So excited about our #CRISPR prime editing work, out @NatureBiotech today – great @JoungLab team work w/ Bret Miller, @ReganSzalay, @johnASeed1, Chris Woodilla, @elizajaneholtz, @Karl_Petri & @JKeithJoung nature.com/articles/s41587-0…
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Prior fellow from the mid-‘90s! Glad to stay connected
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ErikSontheimerLab retweeted
Learn more about who we are, what we do and why we do it: vimeo.com/749675163 #OneIntellia
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Great stuff Mo, @davidrliu, @_ShannonMMiller and team, congrats!
Replying to @MoKhalilLab
4/n We looked to Cas9 orthologs from other organisms as starting points. Nme2Cas9 from N meningitidis stood out. As characterized by @ESontheimerLab & others, this ortholog has natural activity on N4CC PAMs and (bonus for delivery!) is more compact than SpCas9 (1082aa vs 1368aa).
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ErikSontheimerLab retweeted
Check out our overview of strategies to clone and sequence small RNAs which is the cover of this months @Curr_Protocols designed by the extremely talented @NATrigg
The latest issue of CP is out! The cover highlights an Overview by @OliviaJCrocker @NATrigg & @ColinConine (@ChildrensPhila and @Penn), who discuss how to design small #RNA cloning workflows in eukaryotes to capture specific small RNAs of interest. ➡️bit.ly/3eaHq8e
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ErikSontheimerLab retweeted
The @somaticediting consortium launched the #SCGEToolkit, a platform housing #data generated from #SCGE studies: novel delivery systems, independent validation studies & effects of #GenomeEditing. Visit the toolkit and share your feedback at scge.mcw.edu/toolkit.
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Thank *you* @ColinConine, this authoritative piece will be very useful for a lot of people! 🙏
Replying to @ColinConine
Thank you @aemonten and @Curr_Protocols for a smooth review and making the manuscript significantly better in the process. Also, @ESontheimerLab for inviting us to write it in the first place.
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