🚨New preprint from Legacy study @TheCrick & @UCLHresearch. ⏩biorxiv.org/content/10.1101/… 👉We asked: "What's a 'normal' COVID vaccine response?" 🤔 Turns out there's 2 kinds of 'normal' in healthy adults 🧐 — and this has implications for protection vs. future variants 🤒.🧵 1/n

🚨We’re hiring 🚨 Exciting opportunity for a talented post-doctoral virologist #SARSCoV2 #Influenza @UKRI_News PROVAC consortium @TheCrick @MaryYiWeiWu COVID Surveillance Unit & @WHO Worldwide Influenza Centre *Please apply and RT* 3rd Feb 2025 👇 crick.wd3.myworkdayjobs.com/…

I’m so grateful to have been awarded 2 Ideas Grants ($2.8M total). I’m really excited to grow my team and see what we achieve over the next 4 years. Both projects are on Streptococcus pyogenes: 1) studying immune responses after infection, 2) developing a man therapy for iGAS.

Our annual report is here and what a year it’s been. With your support we have achieved: - £11.07 million spent on research, awareness and education, bringing our total research contribution over the last 10 years to £71m! - 2,680 people joined #TeamKidney raising £1.3m for research - 278 volunteers gave their time, their skills and their voice - 56 new research grants were awarded Sandra Currie, chief executive said: "We appreciate every donation that has enabled this, increasing our research investment over the year to almost £11 million. Every day I am reminded of the urgency of our work. Thank you for being part of making it count – we are so grateful for your ongoing support." Read the full report here: bit.ly/3MNNKQi [Image description: Professor Grazia is in a white lab coat and wearing blue latex gloves. She is smiling while holding a sample in a laboratory. She has short blonde hair and is wearing glasses. 'OUR ANNUAL REPORT. We are more essential than ever.' overlays the image.]

Now open! Incl an IgA nephropathy project in my group. We will fill in gaps in pathogenesis, aiming to better match new/upcoming drugs to each patient, and to find angles for next generation of treatments to remedy. Please get in touch if you want more info.

Out today: @UCLHresearch @TheCrick Legacy study collaboration with @adamjkucharski @timwrussell @LSHTM Infection and serological surveillance data Bayesian model = Real-time estimates of antibody response to emerging variants @TheLancetInfDis @MaryYiWeiWu @Hermsnz @EdjCarr

100% out of my comfort zone, but an honour & a privilege to be asked to speak at #Drivingdiscoveries today. Sharing my inner most thoughts & fears was hard, but essential to do so to give an understanding of why the research funded by @Kidney_Research is so imperative.

Our review on the pathogenesis of IgA nephropathy and implications for treatment, out now in Nature Reviews Nephrology @NatRevNeph. Link to the full text here: rdcu.be/dSXxz @Suceena @haresh11 @IgAN_JBarratt

LFDs are of course great for lots of pathogens. But we tested 5 different commercial #Mpox *antibody* LFDs to see their utility for diagnostic/surveillance use, and they aren't great...from 0% to 56% sensitive! thelancet.com/journals/lanin…

Megan Richter Paralympic champion! @unibirmingham @BritishTri @ParalympicsGB

The primary piece from my PhD on cystic kidney disease is out today in @jclinicalinvest! jci.org/articles/view/181467 The full thread discussing the paper is linked in the tweet below. As always many thanks to @The_MRC and @GenomicsEngland, @RenalGenomics and many more!

Incredibly excited for the launch of Pathoplexus, which I've spent quite a bit of time helping with over the past year. New, open-source, infrastructure for sharing viral sequence data!

Lots of summer #Covid about. If your are immune vulnerable and eligible get some tests in to ensure you get treatment early if you test positive 👇

Crick researchers in @bealelab have figured out how cells can detect when their compartments get damaged or infected. crick.ac.uk/news-and-reports…

Thank you WACCBIP for the opportunity to present this work! #WACCBIPis10 #WRC2024 #WRC24 Happy 10th Anniversary!

Our latest study: beginning to highlight the difficulties caregivers can face picking up their child’s prescriptions. We need to have a conversation about how to tackle this issue bmjpaedsopen.bmj.com/content… @AhchPharmacy @louise_oni @BrackenLouise @Andrea_Gi11 @AlderHey

We are delighted to announce that Professor Edith Heard has been appointed as our new director and chief executive! Edith, who is currently director-general at @EMBL, will succeed Paul Nurse in leading the Crick from the summer of 2025. 🔗 crick.ac.uk/news/2024-07-09_…

A privilege and honour to receive the Raine award and I hugely enjoyed sharing our science at #UKKW2024

Please come along or register virtually for this magnificent event and discussion of the latest scientific evidence for cancer initiation and progression and how one day….just one day… we might stop cancer from initiating in the first place

London Renal Transplant Surgical Fellowship- exciting 2-year specialised fellowship in renal transplantation (& dialysis access surgery, pancreas transplant & multi-organ retrieval) 2 London centres: @ImperialNHS @RoyalFreeNHS @Transplant_Ayaz