@Emma_S_Chambers profile picture
Dr Emma S Chambers @Emma_S_Chambers

Senior Lecturer @blizard_inst. I am an immunologist. My lab works on life-course immunology with a focus on barrier immunity. she/her

Joined January 2015
  • Tweets 776
  • Following 1,048
  • Followers 1,366
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Dr Emma S Chambers@Emma_S_Chambers
7 Oct 2024
I am so excited to start my new @Barts_Charity funded project investigating how menopause and HRT impacts upon immunity. But we are in need of volunteers to help with the study :)
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This is my new paper on menopause ageing monocytes and how HRT can prevent immune ageing :) So happy that is out :) qmul.ac.uk/media/news/2025/m…

Hormone replacement therapy may help restore immunity in menopausal women

qmul.ac.uk
Eric Topol
@EricTopol
9 Oct 2025
Hormone replacement therapy helps restore immune function in menopausal women, reducing inflammaging and preserving monocyte function. open-access onlinelibrary.wiley.com/doi/… Extends what I previously summarized from immune system clocks erictopol.substack.com/p/new…
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Replying to @GNRailUK
@GNRailUK just had a very irritating experience at your train station in watton. All the machines can't take card as the internet is down. I asked at the ticket office what to do, and very unhelpful she said just use the Trainline app. Why isn't there a plan in place for this?
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The ticket office says it was like this yesterday. Why hasn't a fix been put in place for people who use watton at stone station? I have missed my meetings now as I didn't have a way of buying a ticket.
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Replying to @GNRailUK
@GNRailUK just had two very strange experiences with ticket inspectors on your trains in two days. The one today didn't speak, just had their earphones in and pointed at things. The one yesterday was wearing no identification at all and then took five minutes to get his id out.
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What is with this poor customer service? Can you encourage your staff to speak and be polite and maybe show id. If I was alone on the train as a female I would have been quite intimidated and afraid.
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Dr Emma S Chambers retweeted
Madhvi Menon@MadhviM
16 Jan 2025
🚨The Menon lab is hiring a Postdoc! Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases @UKRI_News @LydiaBeckerIII 🗓️Apply by Jan 29th Please help spread the word! jobs.manchester.ac.uk/Job/Jo…

Research Associate in Mucosal Immunology :Manchester

jobs.manchester.ac.uk
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Dr Emma S Chambers retweeted
Dr Louisa James@louisakjames
19 Dec 2024
***Fully funded PhD position*** @blizard_inst with myself and @Giovannoni62497 to investigate CD40 signalling in Epstein Barr Virus-infected B-cells in people with multiple sclerosis. Please spread the word! findaphd.com/phds/project/cd…

CD40 ligand and EBV-infected B-cells in patients with multiple sclerosis at Queen Mary University...

PhD Project - CD40 ligand and EBV-infected B-cells in patients with multiple sclerosis at Queen Mary University of London, listed on FindAPhD.com

findaphd.com
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This week I am at the @BTSrespiratory Winter Meeting #BTSWinter2024. I am looking forward to discussing my new work on the influence of old age on asthma immunephenotype tomorrow morning at 8.50am in the discovery science session.
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Dr Emma S Chambers retweeted
Connelly Lab@ConnellyBioEng
18 Nov 2024
We're pleased to share our new preprint on modelling dynamic immune responses in human skin! It has been a tremendous effort from everyone involved and we're excited to continue this new direction of research in immuno-competent skin models. biorxiv.org/content/10.1101/…

Replicating dynamic immune responses at single-cell resolution within a microfluidic human skin...

The intricate immunological functions of human skin involve the interplay between multiple different cell types as well as dynamic trafficking of leukocytes in and out the tissue, both of which are...

biorxiv.org
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Dr Emma S Chambers retweeted
Akbar Lab@AkbarLab
8 Nov 2024
Our newest paper is out! 🚨 We have uncovered multiple cellular senescence-associated defects in melanocytes and other cell types in Familial Melanoma Syndrome (FMS) patients with a p16 defect that makes them more susceptible to developing melanoma ⬇️ onlinelibrary.wiley.com/doi/…

Multiple outcomes of the germline p16INK4a mutation affecting senescence and immunity in human skin

(a) In the skin fibroblasts are a key source of SASP production, with melanocytes having significantly less production. In healthy individuals, senescent fibroblasts play a major role in attracting...

onlinelibrary.wiley.com
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Dr Emma S Chambers retweeted
Lifespan News@LifespanNews
21 Oct 2024
The newest researcher investigated the biology of skin cells taken from people who don’t produce the senescence-related compound p16. lifespan.io/news/the-reason-… by Josh Conway @ucl @Emma_S_Chambers #aging #cancer #SASP #FMS
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I am so excited to start my new @Barts_Charity funded project investigating how menopause and HRT impacts upon immunity. But we are in need of volunteers to help with the study :)
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If you are between 40-60 years and are happy to come to Whitechapel for a one off blood donation, please do get in contact to received more information
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Just back from annual leave to see that I have been promoted to Senior Lecturer :) @blizard_inst
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I just want to add my thanks to my lab members, colleagues and funders for the support since setting up my lab in 2020 :)
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We just had a lovely lab outing to the sky garden in London. I really appreciate all the hard work my lab members have put in over the past year :)
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Dr Emma S Chambers retweeted
Diabetes UK: South East Coast and London@SECandLondon
6 Jun 2024
Diabetes UK's Havering Volunteer Support Group's next meeting features Dr Emma Chambers giving a talk on “Ageing and Immunity.” 📅 Monday, 17 June 2024 📍 Large Hall, 24 North Street, Hornchurch RM11 1QX 🕗 8pm 🎫 £2, which incl. tea and coffee For more info call: 01708 935779
Dr Emma Chambers

ALT Dr Emma Chambers
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Dr Emma S Chambers retweeted
CARINA Network@CARINAnetwork
10 Jun 2024
⏰ Our #EarlyCareer Development #Grant applications close this week! We are offering these grants to #ECR CARINA members to boost their #ProfessionalDevelopment & help them reach their #CareerGoals 🤩 Apply by 23:59 BST this Wed 12 June 👉bit.ly/3xZO3nL
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This is such an important article and something I feel passionately needs to improve.
Pallett Lab UCL@pallett_lab
27 May 2024
As #UKRIFLFs navigating travel w/ caring responsibilities myself @DrLauraWolz & @CarterL_J are calling for accelerated change - sharing insights into challenges faced highlighting personal experiences & proposing a strategy for institutions @NatureCareers nature.com/articles/d41586-0…
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I am delighted to say that our new paper investigating the impact of an individual's characteristics on covid-19 vaccine immunogenicity is now published @npjvaccines doi.org/10.1038/s41541-024-0… @blizard_inst (1/6).

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more replies
In keeping with previous work in the field, we observed that age was an important factor for vaccine immunogenicity. Increasing age was independently associated with lower anti-S antibody titres post-vaccination. No difference in cellular antigen specific immunity was (5/6)
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Finally, we did not see any effect of biological sex or BMI on vaccine immunogenicity. However, we did fine that males had increased LPS stimulated IL-6 production and had lover naïve CD4 and CD8 T cells as compared to female (6/6).
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