Why does Science need Philosophy and Metaphysics? In the first episode of our new podcast, @HamdinSula and I explore this question together with our guest—Father Francis Tiso. open.spotify.com/episode/0pH…

Its all about scale

Together with UC Berkeley we are announcing the laser phase plate - a breakthrough in atomic resolution imaging. This is the brightest continuous wave laser in the world, 100 million times the intensity of the surface of the sun. Phase contrast plays an important role in microscopy, but it was thought close to impossible for electron microscopy, where it would require interfering with an electron beam. Holger Mueller and Robert Glaeser proposed exactly this using a standing wave laser. It has taken over 15 years to make this a reality. Biohub partnered with UC Berkeley and Mueller to support this work and to engineer and build the technology. Contrast has been the critical barrier to achieving atomic resolution imaging of the cell. In cryo-electron tomography, a cellular imaging technology that uses electron microscopy, the low contrast makes it impossible to resolve anything but the largest proteins within their cellular context. The laser phase plate removes that barrier. With advances in AI this breakthrough in contrast will start to open up a new frontier in structural biology, that will allow us to see the molecular machines of the cell, and how they assemble into far more complex and dynamic systems, and understand how they work.

👀

This is biblical. A woman in her eighties. Ten years into Alzheimer's. Hadn't spoken a full sentence in five years. Takes one, 5 gram dose of psilocybin. She slept 19 hours and woke up and spoke for hours about her life, recognized family and held real conversations. She regained bladder control after five years, walked on her own. and dressed herself. Gains held for weeks.

🌈Budapest was celebrating the end of QuEBS 2026 with us.

BREAKING NEWS: according to CloudFlare Radar Data, Agentic traffic has SURPASSED human traffic across the worldwide internet for HTML webpages.

We're heading to QuEBS 2026 (the 15th International Workshop on Quantum Effects in Biological Systems). In addition to participating in the event, our own contributor @EnactJohnny will be presenting on the Quantum Biology DAO and how decentralized science can contribute to the advancement of the field. QuEBS brings together researchers across quantum physics, biology, chemistry, biophysics, and engineering to explore how quantum phenomena influence living systems and how those insights can inspire next-generation technologies. We're excited to connect with scientists from around the world, share the DAO's approach to advancing quantum biology through DeSci, and learn from the latest developments across the field.

Recipe for fundraising, hiring, selling: Walk into every room like God sent you to do that work

Most of the time, people who are obsessed with “self-realization” and “dissolving the ego” are actually very much obsessed with the self. Focus on the self, focus inward, and so on.

What does it take for a new idea to become science? Max Planck: 'A new scientific truth does not triumph by convincing its opponents and making them see the light, but rather because its opponents eventually die and a new generation grows up that is familiar with it'

What can the interface of sleep, consciousness, and advanced meditation teach us? Announcing the publication of “Advanced Meditation, Sleep, and Consciousness Science: An Emerging Frontier,” in Neuroscience & Biobehavioral Reviews. Across many contemplative traditions, sleep has long been viewed not as unconscious downtime, but as a powerful domain for mind training. Modern science is only beginning to explore this possibility. In our new article, we argue that uniting advanced meditation, sleep, and consciousness science opens a new frontier for understanding the mind across the full arc of both waking and sleeping life. In this view, consciousness is not simply “on” or “off,” but dynamic, trainable, and transformable across many states of experience. The broader implications of this integrated perspective are profound. If awareness can be systematically cultivated not only during waking practice, but also across sleep states –for example through lucid dreaming, clear light sleep, and sleep-wake transitions – then this may represent a largely untapped dimension of human development, one that at least in some cases ancient traditions described in detail and that now science is only beginning to investigate. I extend my deep gratitude to first author Clarita Bonamino @BonaminoClarita and our collaborator Clara Hausen, as well as to the contemplative practitioners and traditions who continue to inspire this work. The full manuscript PDF is included in the comments below ⤵️ May this work benefit many 🙏

Scientists are raising funds on @ResearchHub to test whether the Wim Hof Method is safe and potentially beneficial for cancer patients. So, we went and interviewed @Iceman_Hof himself. We asked him about breathwork, cold exposure, and what science still hasn't explained about his method. Support the proposal here: researchhub.com/proposal/445…

We're all unpaid actors in some giant script that we didn't write.

“The Truth might be uncomfortable, but it is not unsafe.” — Anji Groen

Called a replication study outcome right, 59% profit. I love this concept. @ResearchHub is cooking ❤️

We just completed our first replication study on @ResearchHub. From preregistration → funding → experiment → results A full scientific lifecycle, run in the open, with community input. We also tested something new along the way: prediction markets for science. Here’s how it played out. 👇

Life hack: Hang around really smart people.

Sci-Hub is an evil website that pirated 85M research papers and made them freely available And now they've added AI to their database to make Sci-Bot. It answers your questions using latest, full-text articles. But DO NOT use it. We should all try to make billion-dollar academic publishers richer. I'm putting the link below so you know how to avoid it.

Harm set, harm get. Negativity produces negativity for those who inflict it.