The mission of our lab is to develop metastasis prevention strategies by understanding the biology of disseminated tumor cells and their microenvironments.

Joined October 2012
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New lab photo!! Standing offer for Dr. Biden to join our lab- she did love the views!!! Unforgettable experience to have ⁦@FLOTUS⁩ visit our lab, learn about tumor dormancy, and how we want to prevent metastasis and develop new curative approaches via ⁦@FredHutch_Met_X
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Ladies and gentleman, debut paper from the superstar lab of Shivani Srivastava…
Excited to share our lab’s latest work in @SciImmunology, examining how CAR-T cells bypass the niches that normally support stem-like subsets in vivo and how this influences their sensitivity to checkpoint blockade.
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Cyrus Ghajar retweeted
19 Dec 2025
😁 Honored to be selected as a CRI Irvington Postdoctoral Fellow (award period 2026-2029) @CancerResearch . I’m incredibly grateful to my mentors @GhajarLab and @EvNewell1 — I wouldn’t be here without their guidance. Excited to continue this work @fredhutch @FredHutch_Met_X
The Cancer Research Institute is honored to share the Winter 2025 Class of CRI Irvington and Immuno-Informatics Postdoctoral Fellows. Meet this new class of visionaries, backed by CRI's urgent commitment to keep progress moving forward: bit.ly/3KOsT2J #CancerResearch
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Beautiful new work driven by star MD/PhD fellow Takahiro Tsuji in Japan’s Wake Laboratory.
10 Dec 2025
Caught in the act: Brain microglia (green) attacking and ingesting tumor cells (red) aacrjournals.org/cancerres/a…
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Cyrus Ghajar retweeted
9 Dec 2025
Last night Adam Kampff, the glue, the light, the catalyst, the builder, the smile, left us. He and his work transformed the lives of many labs, scientists, students. He kept inspiring and being generous until his last transformation, and worked tirelessly to set up a foundation to continue the work. He once said when moving from Lisbon to London "I am not leaving, I am just spreading the good work further". Thank you Adam! Thank you!
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Cyrus Ghajar retweeted
Hiring: PostDoc in Tissue Clearing & 3D Histopathology 🧪🖥️ My lab at Helmholtz Munich is seeking a highly motivated PostDoc/Scientist to strengthen our efforts in advanced imaging of cancer tissues. Key Responsibilities: Develop & Optimize: Create tissue-clearing protocols for human cancer samples. Image: Perform 3D microscopy using light sheet and confocal systems. Analyze: Collaborate with computational scientists to integrate multi-modal datasets and quantitative readouts. Innovate: Explore novel experimental approaches for cancer tissue clearing. Requirements: We are looking for candidates with strong hands-on expertise in tissue processing, H&E/IHC/IF staining, and handling biological imaging datasets. Experience with colorectal cancer biology and supervising junior colleagues is highly advantageous. Why join us? Work in an intellectually stimulating environment with flexible work schedules and extensive career development programs. 📩 To Apply: Please email your application (CV, transcripts, motivation letter) to thomas.schubert@helmholtz-munich.de and ali.erturk@helmholtz-munich.de by 31.12.2025. #Histopathology #TissueClearing #LightSheetMicroscopy #PostDoc #ScienceCareers #Munich
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Cyrus Ghajar retweeted
Too many men die of prostate cancer. We miss you John. We discovered a new way of attacking androgen receptor driven prostate cancers that will lead to new therapeutics. This was a wonderful collaboration with @li_haolong and Felix Feng (rest in peace). doi.org/10.1038/s41588-025-0…
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Cyrus Ghajar retweeted
20 Oct 2025
We have launched a faculty search for an individual who will transform our basic understanding of cancer metastasis through the integration of computational approaches. Deadline is November 3rd. Please RT far and wide! nature.com/naturecareers/job…
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Cyrus Ghajar retweeted
Join us in sunny Ventura California for the 2026 GRC Autophagy meeting ! Excited to co-chair with @FloreyLab and vice chairs @KnVelsrud @RobertoZoncu Keynote speakers incl. @EileenWhitePhD @iDikic2 and @sharontooze01 - Registration is now open : link⬇️ grc.org/autophagy-in-stress-…

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Cyrus Ghajar retweeted
Had to make some updates 👀 💡 Honoring four more Nobel Prizes for @UCBerkeley after last week’s award announcements. #SmartAndTough #GoBears
Berkeley’s got the best and brightest 💡 Honoring the 59 Nobel Prizes and counting won by Cal affiliates on our helmets this weekend. #SmartAndTough #GoBears
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Cyrus Ghajar retweeted
New from the Bullman Lab in Cancer Cell! Tumor-infiltrating bacteria, including Fusobacterium, disrupt cell-cell contacts & trigger quiescence, uncovering a pathway of bacteria-induced therapy resistance 🔗 cell.com/cancer-cell/fulltex… Thanks to @MDAndersonNews, @FredHutch, @UTEPnews
Bacteria can impact cancer progression and treatment. A new study shows how a particular bacteria can induce a reversible state in cancer epithelial cells, which allows tumors to evade the immune system and resist chemotherapy: bit.ly/4olyzz4 @BullmanLab #EndCancer
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Cyrus Ghajar retweeted
Our work describing the metabolic roles of serum for cancer cell proliferation is now out @jbiolchem! Congrats to Oliver and Eric and many thanks to the editor and reviewers for a thoughtful and efficient review process. See here: sciencedirect.com/science/ar…

Excited to share a new preprint, where we evaluate the functional contributions of serum for cancer cell proliferation. Inside: A broadly applicable serum-free media, Quantitative lipid uptake characterization, Evidence lipid scavenging > synthesis for cancer cell proliferation
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Cyrus Ghajar retweeted
11 Oct 2025
Cancer researcher on the faculty job market? @fredhutch
Fred Hutch's Human Biology Division is recruiting a tenure-track Assistant or Associate Professor to lead a laboratory-based research program focused on the biological mechanisms of solid tumor cancers and their clinical translation. Learn more and apply: apply.interfolio.com/174007
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Cyrus Ghajar retweeted
7 Oct 2025
Our latest immunology study reveals rheumatoid arthritis begins silently – attacking the immune system years before symptoms appear. This breakthrough opens the door to preventing RA before it begins. This 7-year study is a result of team science at its best! Scientists at the @AllenInstitute, in collaboration with @BRIseattle, @CUAnschutz, and @UCSanDiego, mapped the earliest immune changes in individuals at risk for RA, shifting focus from reactive treatment to early intervention. I’m proud of the Allen Institute team for pushing science toward earlier detection and better outcomes for patients. alleninstitute.org/news/new-…
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Incredible opportunity in an incredible lab ⬇️
2 Oct 2025
Are you on the market for a postdoctoral fellowship? If you are interested in studying the post-transcriptional mechanisms of cancer check out the @HsiehLab @FredHutch Learn more about our group here: research.fredhutch.org/hsieh… Apply here: careers-fhcrc.icims.com/jobs…
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Do you want to study disseminated tumor cell fate choices in the most sophisticated models? Then do I have the postdoc opportunity for you... nature.com/naturecareers/job… Please share with anyone you think may be interested!
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Cyrus Ghajar retweeted
New paper from my lab and @JShendure lab! Led by the brilliant @Zukailiu and @CXchengxiangQIU. We tackle a question: How do anterior and posterior progenitor cells cooperate to self-organize into an embryonic structure (termed AP-gastruloid)? (1/n) biorxiv.org/content/10.1101/…
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Cyrus Ghajar retweeted
27 Sep 2025
Looking for a #postdoc fellowship that combines cutting edge technology, cancer biology, and radiation oncology? Join us and study the biology of ultra-high dose rate FLASH Radiotherapy in beautiful Seattle WA! #postdocjobs @uwradonc @fredhutch apply.interfolio.com/173684
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Cyrus Ghajar retweeted
The Rajan Lab at Fred Hutch (Seattle) is recruiting a staff scientist and postdoc to study fat–brain communication, innate immunity, mitochondrial signaling, and brain senescence. Great team, great environment. Apply here: careers-fhcrc.icims.com/jobs…

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Cyrus Ghajar retweeted
Excited to share our new preprint introducing CenSegNet, a deep learning framework for high-throughput, spatially resolved, single-cell centrosome profiling in heterogeneous tissues. Co-led by brilliant PhD students, Jiaoqi Cheng & Keqiang Fan. 1/3 biorxiv.org/content/10.1101/…
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Cyrus Ghajar retweeted
Today, I would like to honor the memory of Roger Y. Tsien, who died on August 24, 2016. His legacy lives with all who use his technologies, including calcium sensors, fluorescent proteins, the acetoxymethyl (AM) ester, & many more! #FluorescenceFriday nature.com/articles/nmeth.40…
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