The distinctive psychopathology of NMDAR-antibody encephalitis compared with primary psychoses: an international, multicentre, retrospective phenotypic analysis - The Lancet Psychiatry thelancet.com/journals/lanps…

✨Calling all early-career & senior researchers‼️ We are planning next year's series of talks and would like to hear your suggestions Are you interested in presenting your own research or have a researcher you would love to hear from? Let us know here: bit.ly/pixie2026

Great talk by @NeedhamNeuro at the 2025 @TBI_REPORTER Assembly on neuroinflammation, IL-6, and TBI, with exciting clinical trials on the horizon.

To shunt or not to shunt, that is the (NPH) question? The first large randomized trial of shunting for normal pressure hydrocephalus (NPH) just dropped in NEJM, and there was clear benefit for walking, and it favored the group receiving shunts. Spoiler alert: Walking improved, however thinking (cognition) and bladder function did not. Key Points: - NPH is a condition usually presenting in older adults where fluid builds up in the brain and it associated w/ trouble walking, memory and thinking challenges as well as bladder incontinence. - Shunting significantly improved walking speed and balance compared w/ placebo. - No meaningful change in cognition or bladder control observed at 3 months. - Risks included subdural bleeding and headaches, underscoring the need for careful follow up. My take: NPH has always been a tricky area for clinicians when trying to decidr 'to shunt or not to shunt.' Here are 5 points that resonated w/ me: 1- Shunting in well selected persons can restore some walking ability in NPH. 2- Thinking did not improve at 3 months. 3- Incontinence showed no clear benefit. 4- Risks to always discuss w/ people considering shunts should include bleeding and headaches (as not uncommon). 5- Walking gains may possibly reduce falls and boost independence, however we must be careful as sometimes improved walking w/o improved balance, can actually trigger falls. nejm.org/doi/full/10.1056/NE… @FixelInstitute @ParkinsonDotOrg @alzassociation @SfNtweets @SfNtweets @NEJM

📣Clinical Research Fellowship📣 Applications open for an exciting Clinical Fellowship in neurology / neuroimmunology / demyelinating disorders with a particular focus on NMOSD at the Walton Centre. Details below:

Prospect’s annual Top Thinkers shortlist has arrived! Chosen thinkers include @anneapplebaum, @RebeccaSolnit, @NesrineMalik and many more. Vote for your favourite—and tell us who should have been on the list but isn’t. prospectmagazine.co.uk/ideas…

📣Job Opportunity📣 Advanced clinical training fellowship in neuroinflammation (MS and NMOSD focussed) at the Walton. For more information, see link below:    healthjobsuk.com/vacancy/678…

🗓️Save the date! We're pleased to announce that Neuroimmunology & MS 2025 research & academic meeting will be held in Edinburgh on 11 - 12th Mar 25. Registration & call for abstracts opening soon! For more info visit our website edin.ac/3NVD9UN #neuroimmunology_MS_25

Optimal anticoagulation timing after ischaemic stroke in patients with atrial fibrillation - The Lancet thelancet.com/journals/lance…

NeuroImage: Epilepsia Partialis Continua in an Adolescent With GAD65 Antibody–Associated Encephalitis: bit.ly/4f6TS3b #NeuroTwitter

Autoimmune Encephalitis and Paraneoplastic Neurologic Syndromes | Neurology Neuroimmunology & Neuroinflammation neurology.org/doi/10.1212/NX…

Teaching Video NeuroImage: Perivascular Tumefactive Neurosarcoidosis of the Basal Ganglia bit.ly/4e8rsos #NeurologyRF

A moving evening with the wisest of men. Intellectually rigorous and generously public spirited. We are lucky to have @DavidOlusoga

The 2025 ABN Clinical Research Training Fellowships are open for applications! 🩺🧠 We encourage the brightest UK neurology trainees in undertaking world-leading clinical neuroscience research 🌟 Interested? Know someone? Info here: theabn.org/page/Fellowship-A…

Thrilled to have been chosen for the best SpR case presentation #ABN2024! Four days of fabulous talks, stimulating topics, and inspiring colleagues @theABN_Info @NeedhamNeuro

With huge thanks to the brilliant Guardian longread team @ClareLongrigg and @davidedgarwolf who have dedicated so much space and time to Sudan, and to all those in Sudan who continue to share their stories and hope for more attention to the disastrous conflict in the country.

Couldn’t be more proud of you @NesrineMalik ❤️ well deserved and super congratulations !

For a full year, the bodies have piled up in Sudan – and still the world looks away | Nesrine Malik | The Guardian theguardian.com/commentisfre…

Anti-IgLON5 disease is a rare autoimmune encephalitis with late onset. Yogeshwar et al. present data suggesting a stronger association with HLA-DQ over HLA-DR, and showing autoimmune reactivity against IgLON5 in a post-translationally modified form. tinyurl.com/enamh8ws

Neurology Podcast: Drs. Jason Crowell & Carles Gaig discuss developing a composite score to assess the severity of the multiple symptoms present in anti-IgLON5 disease. Listen now: bit.ly/3Ti94Rt Read the article: bit.ly/3TLN5nH #NeuroTwitter @jasonlcrowell