If systemic hypotension was the sole cause of ischemic hepatitis, every patient in the MICU would have ALT >500
But the incidence is 1 in 50
You need right heart failure, congestion, that exceeds portal pressure. Then the systemic bp drop can be transient or relative
Being a hepatologist means you diagnose a LOT of heart failure
1. Ascites, often with high total protein
2. ALT > 400 is most often due to ischemic hepatitis. This is caused most by venous congestion and less by systemic hypotension. echo often unhelpful