Physician scientist in HOPP and DOM/Lymphoma at Memorial Sloan Kettering. Our lab studies the metabolic control of cell fate and oncogenesis. Tweets are my own.
It was an honor to be part of this team effort to understand how some cancers develop resistance to IDH inhibitors. Thank you Alan Shih, Eytan Stein, Craig Thompson, and Ross Levine! @rosslevinemd @sloan_kettering #mskccnature.com/articles/s41586-0…
Excited to share our collaboration w/ @bradleybio demonstrating that pharmacologic modulation of splicing induces immunogenic neoantigens and augments response to checkpoint blockade. Jointly led by @SXLuLab, @ejdeneef, @jdthomaslab. Out today in @Cell:
cell.com/cell/fulltext/S0092…
So proud that the first paper from @VardhanaLab, an equal collaboration with @Ron_cology and Alex Huang's lab, is out today in @NatureMedicine: rdcu.be/ckYst. I posted a long tweetorial about this study when it was a preprint, but a few additional thoughts:
Please read and use our latest work with @CompProteomics on agnostic chemical proteomics: Discovery of Protein Modifications Using Differential Tandem Mass Spectrometry Proteomics pubs.acs.org/doi/10.1021/acs…
Congratulations to my very first graduate student @SylviaZohrabian for receiving the @DeptofDefense Horizon Award! A welcome piece of good news in a difficult year. @WeillCornellGS @sloan_kettering. Meet Our 2021 Fellows... gradschool.weill.cornell.edu…
Congratulations to my very first graduate student @SylviaZohrabian for receiving the @DeptofDefense Horizon Award! A welcome piece of good news in a difficult year. @WeillCornellGS @sloan_kettering. Meet Our 2021 Fellows... gradschool.weill.cornell.edu…
#CancerCare can’t wait. If you or someone you know has symptoms or has been diagnosed with cancer, please don’t wait. The #cancer experts at Memorial Sloan Kettering are here for you. Connect with an MSK cancer expert. bit.ly/32SFSHX#MSKAlways
For all aspiring cancer researchers, check out the PhD program @GSKGradSchool @sloan_kettering. It’s an amazing and supportive environment to train in!
New Review online! T Nielsen &co discuss how the disease biology of many sarcomas is driven by #chromatin pathway alterations w/ a view to use this knowledge to better develop targeted therapies for patients with #sarcoma.
go.nature.com/30Qkylk
@NatResCancer #DNAmethylation
I am pleased to share our paper out today in @Cancer_Cell identifying a novel cancer cell state that is central to phenotypic transitions - and that seems to play a key role in tumor progression and drug resistance. cell.com/cancer-cell/fulltex…
I am so excited that our paper exploring how metabolic dysfunction contributes to T-cell exhaustion is out today in @NatImmunol. A thread (1/X): rdcu.be/b5AAg