Assistant Professor @UNC_Lineberger. T cell differentiation during infection & cancer.

Joined January 2018
Photos and videos
Justin Milner retweeted
🕰️🚆🦠 Excited to share our new preprint: “Optimal transport fate mapping resolves T cell differentiation dynamics across tissues”! We use OT to infer realistic CD8 T cell differentiation and migration trajectories from scRNA-seq timecourses. biorxiv.org/content/10.64898… 1/

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Justin Milner retweeted
Huge thanks to my my mentors Natalie Stanley (@natstann, @comp_cy) & Justin Milner (@JJMilnerLab) and to my co-authors Genevieve Mullins, Will Green (@greenwilliamd), Huitong Shi, Haidong Yi, and Kay Chung (@HKayChung1) 🙏 10/
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Justin Milner retweeted
Replying to @biorxivpreprint
@biorxivpreprint Optimal transport fate mapping resolves T cell differentiation dynamics across tissues biorxiv.org/content/10.64898… @JJMilnerLab @UNC_Lineberger @natstann
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Justin Milner retweeted
Replying to @biorxivpreprint
@biorxivpreprint Latent Regulatory Programs Generate Synthetic T Cell States with Enhanced Therapeutic Potential @JJMilnerLab @Pratt__Brandon @UNC_Lineberger biorxiv.org/content/10.64898…
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Justin Milner retweeted
Amazing work by talented graduate student @Pratt__Brandon and team from the @JJMilnerLab @HKayChung1. Be sure to check it out how they devised a way to unlock the therapeutic potential of CD8 T cells!
Latent Regulatory Programs Generate Synthetic T Cell States with Enhanced Therapeutic Potential biorxiv.org/content/10.64898… #biorxiv_immuno
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Justin Milner retweeted
Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment @ImmunityCP @JJMilnerLab cell.com/immunity/fulltext/S…
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Justin Milner retweeted
Excited to share the first of many works out of @JJMilnerLab. Be sure to check it out! Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment: Immunity cell.com/immunity/fulltext/S…

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Justin Milner retweeted
12 Feb 2025
Thrilled we were part of #KSTCells25 @KeystoneSymposia in Vancouver 🇨🇦 and reunited with T cell friends & colleagues! Huge thanks to co-organizers @theLundLab, @Joshilabyale & @DelgoffeLab. We can’t wait for the next one!!
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Justin Milner retweeted
Delighted to share that our feature selection method for improving inference of cellular trajectories is out today in @NatureComms! Biggest thank you to @natstann @purvislab @WStallaert @JJMilnerLab team 😊 Paper: rdcu.be/dCVZA . 🧵below.

Super excited to introduce DELVE (github.com/jranek/delve), an unsupervised feature selection method for improving inference of developmental or disease trajectories from noisy single-cell data: biorxiv.org/content/10.1101/… 😊(1/8)
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Justin Milner retweeted
Thrilled to work with such talented and dedicated group of colleagues!! @derlabunc @YehlabUNC @bryant_kl @JJMilnerLab #adriennecox #ashwinsomasundaran #hjkim
It's World Pancreatic Cancer Day. To all affected by #PancreaticCancer, know that we are here with you 💜 Today and every day, our dedicated team @UNC_Lineberger works to find better ways to treat this devastating disease. #WPCD
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Justin Milner retweeted
Congratulations @alecplot for winning a best poster award at data science day for work predicting CD8 T-cell fates with @JJMilnerLab :) Truthfully, this a picture from last week, but is the same poster. Great job Alec.
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Justin Milner retweeted
So pleased to announce that @JJMilnerLab has earned our 2023-24 @theNCI SPORE CEP Award for his project, "Molecular regulation of T cell activity in pancreatic ductal adenocarcinoma." Congratulations, Dr. Milner, we're excited to watch your progress this year! @UNC_Lineberger
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Justin Milner retweeted
Happy to share that our story is out! @SciImmunology Our study demonstrates that sustained CD28 signaling, is required to maintain PD-1 CD8 T cells during chronic antigen stimulation (1/) science.org/doi/10.1126/scii…
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Justin Milner retweeted
Paper alert from the @GoldrathLab 🚨 (Link at the end). 🧵 (1/10) >>
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Here at UNC M&I, we're proud of our inspiring community of scientists who are changing the way we think about infections! We teamed with @kathaskfilms to provide an inside-look at how they do it. 📽️🔬 Full video: youtu.be/yHLFE7oTh7M and at med.unc.edu/microimm/ @UNC_SOM
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Justin Milner retweeted
Finally, @Pratt__Brandon & @JJMilnerLab put these two exciting papers in context with an outstanding @ScienceMagazine Perspective! bit.ly/Sci_adi3357
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Justin Milner retweeted
14 Dec 2022
Our work on ENTER is finally out @CellCellPress! Like📱that can 📷📞🎧, ENTER is a modular viral platform that unifies multiple applications: ⭐️Decode Ligand-Receptor interaction ⭐️Receptor-specific cargo delivery ⭐️Link receptor specificity with cell state at single cell
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Justin Milner retweeted
So thankful for this honor! @UNC_Lineberger @UNCPancreas
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Justin Milner retweeted
Our new preprint is out! This was a collaborative work between us and Dr. D’Imperio Lima at @icb_usp. Later today I will do a thread! T cell-specific P2RX7 favors lung parenchymal CD4 T cell accumulation in response to severe lung infections biorxiv.org/content/10.1101/…
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