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Lippincott-Schwartz Lab @JLS_Lab

Curated by the members of the Lippincott-Schwartz lab at Janelia. Tweets from Jennifer will be signed JLS.

Joined March 2019
  • Tweets 118
  • Following 313
  • Followers 6,891
8 Photos and videos
Lippincott-Schwartz Lab retweeted
American Society for Cell Biology@ASCBiology
20 Oct 2024
Check out Eva Nogales' inspiring journey in this #IAmASCB video! As part of #CellSpeak week, learn how her work is advancing cell biology and shaping the future of science. Watch now: youtu.be/aDr8fI5mN4g #CellSpeak #SciComm #publicengagement #cellbiology #citizenscience
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Lippincott-Schwartz Lab retweeted
HHMI | Janelia@HHMIJanelia
18 Oct 2024
🥼 Carolyn Ott, a senior scientist in the @JLS_Lab, is featured in @TheScientistLLC, discussing new research she co-authored that used volume electron microscopy to examine how primary cilia on developing neurons change during differentiation. ⬇️ the-scientist.com/new-cilia-…

New Cilia Disassembly Pathway Revealed in Maturing Neurons | The Scientist

Volume electron microscopy reveals a novel cellular process that is critical for healthy brain development, with implications for tumor formation.

the-scientist.com
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Lippincott-Schwartz Lab retweeted
American Society for Cell Biology@ASCBiology
20 Oct 2024
#CellSpeak has begun! From October 20-26, share your science and engage with the public. Use #CellSpeak and tag @ASCBiology to showcase your work. Let’s bridge the gap between scientists and society! Get involved: ascb.org/society-news/cellsp… #SciComm #publicengagement #cellbiology
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🚨The #ASCB Image & Video Contest is BACK! 🚨 Got stunning #CellBiology visuals? 🎥🧫 Submit your images or videos by Nov 11 for a chance to win amazing prizes and be featured at #CellBio2024! Don’t miss out—showcase your work to the world! 🔬#ScienceArt ascb.org/2024-ascb-image-con…
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Lippincott-Schwartz Lab retweeted
Jonny Nixon-Abell@AbellJonny
25 Jan 2024
✅💡 very happy to have this paper finally out. Chris and I started working on this project in 2017…so great to get this across the line at last! nature.com/articles/s41586-0…

Motion of VAPB molecules reveals ER–mitochondria contact site subdomains

Nature - High-speed molecular tracking is integrated with three-dimensional electron microscopy to map the diffusion distribution and ultrastructure of endoplasmic reticulum-mitochondria contact...

nature.com
Jonny Nixon-Abell@AbellJonny
6 Sep 2022
🔬🚨 New preprint from @cjobara and myself during our time together in the @JLS_Lab and Blackstone lab. Motion of single molecular tethers reveals dynamic subdomains at ER-Mito contact sites...a (belated) thread🧵...(1/9)
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Henne_Lab@HenneLab
24 Jan 2024
Congrats to @cjobara and @JLS_Lab for this very interesting study that uses single molecule tracking of VAPB to examine ER-mitochondrial contacts and protein mobility through the ER network. nature.com/articles/s41586-0…
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Two new papers show how and why neurons in the cerebellum disassemble #cilia as they mature. With @SaikatCilium and @darbly. biorxiv.org/content/10.1101/… biorxiv.org/content/10.1101/…

Permanent deconstruction of intracellular primary cilia in differentiating granule cell neurons

Primary cilia on granule cell neuron progenitors in the developing cerebellum detect sonic hedgehog to facilitate proliferation. Following differentiation, cerebellar granule cells become the most...

biorxiv.org
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Lippincott-Schwartz Lab retweeted
Jonny Nixon-Abell@AbellJonny
20 Nov 2023
🍻🍻🍻Well folks…some great news to share. Incredibly happy to announce that I’ll be starting my group @TheCIMR in Feb2024 with funding from a @wellcometrust CDA. A massive thanks to CIMR and my various mentors @ProfKHarvey, @JLS_Lab, Craig Blackstone and Peter St George Hyslop!
The CIMR@TheCIMR
20 Nov 2023
Delighted to be welcoming two new PIs to CIMR! Both Jonathon Nixon-Abell and @melissagammons1 are recipients of @wellcometrust Career Development Awards; we're looking forward to working with both cimr.cam.ac.uk/news/cimr-wel…
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Lippincott-Schwartz Lab retweeted
allen institute@AllenInstitute
2 Nov 2023
Check out this fascinating preprint about cilia in neurons, astrocytes, and oligodendrocyte precursor cells by our researchers (incl. @CollmanForrest, @JoJoBuchanan1, @AgnesLBodor), @JLS_Lab, and collaborators! 🔗 biorxiv.org/content/10.1101/…
Lippincott-Schwartz Lab@JLS_Lab
2 Nov 2023
Excited to share our new paper on primary cilia in the brain! 🧠 We used advanced #EM volumes from #connectomics to study primary cilia structure and location in mouse visual cortex. They’re not just in neurons but also in astrocytes and OPCs! (1/2)
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Excited to share our new paper on primary cilia in the brain! 🧠 We used advanced #EM volumes from #connectomics to study primary cilia structure and location in mouse visual cortex. They’re not just in neurons but also in astrocytes and OPCs! (1/2)
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We find that cilia pass close enough to synapses to detect spillover! With @AllenInstitute, @aaron_t_kuan, @darbly. biorxiv.org/content/10.1101/… (2/2)

Nanometer-scale views of visual cortex reveal anatomical features of primary cilia poised to detect...

A primary cilium is a thin membrane-bound extension off a cell surface that contains receptors for perceiving and transmitting signals that modulate cell state and activity. While many cell types...

biorxiv.org
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Lippincott-Schwartz Lab retweeted
Lorena Benedetti@LorenaBenedet15
7 Sep 2023
For all interested in 3D visualization, remember to sign up to Igor's webinar: ascb.org/ascb-meetings/art-i…. He is going to show us how he does his magic! It's next week already 😱
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Lippincott-Schwartz Lab retweeted
Sarah Cohen@cohenlaboratory
29 Apr 2023
New preprint from the Cohen lab! Led by @iawindham, we found that astrocyte #APOE can traffic to #LipidDroplets, where it modulates LD composition and size: biorxiv.org/content/10.1101/… 1/12

APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size

The E4 variant of APOE strongly predisposes individuals to late-onset Alzheimer’s disease. We demonstrate that in response to neutral lipid synthesis, apolipoprotein E (APOE) in astrocytes can avoid...

biorxiv.org
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Lippincott-Schwartz Lab retweeted
HHMI | Janelia@HHMIJanelia
3 Dec 2022
🚨 Don’t miss talks by @ManuPra18599785, @mengwang939, @MishaAhrens, @ZerialLab and @ErikaHolzbaur in a special session on 4D Cellular Physiology at #cellbio2022, moderated by @JLS_Lab. 🗓️ Sunday, Dec. 4 @ 3:30 pm. Room 147A. More info ▶️ plan.core-apps.com/ascbembo2… @ASCBiology
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Lippincott-Schwartz Lab retweeted
HHMI | Janelia@HHMIJanelia
1 Dec 2022
🗓️ Add our session on 4D Cellular Physiology to your #CellBio2022 schedule. Moderated by @JLS_Lab, with talks by @ManuPra18599785, @mengwang939, @MishaAhrens, @ZerialLab & @ErikaHolzbaur. Sunday, Dec. 4 @ 3:30 pm in Room 147A ▶️ plan.core-apps.com/ascbembo2… @ASCBiology
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Lippincott-Schwartz Lab retweeted
Danfeng Cai@DanfengCai
29 Oct 2022
In our new preprint, we reported that endogenous YAP condensates are sensitive to Hippo pathway and cytoskeleton regulations. We also used single molecule tracking to find out that YAP condensates are viscous hubs that can slow down YAP diffusion. Congrats @SiyuanHao99 et al
bioRxiv@biorxivpreprint
26 Oct 2022
YAP condensates are highly organized hubs for YAP/TEAD transcription biorxiv.org/cgi/content/shor… #bioRxiv
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Lippincott-Schwartz Lab retweeted
Aubrey Weigel@avweigel
5 Oct 2022
Ever wanted to learn how to segment organelles in vEM? Or how we (@COSEMdata/@CellMapPT) generate training data for ML efforts? Look no further! You can find it all here in our recent protocol protocols.io/view/amira-anno… #teamscience #projectteams #openscience
organelle segmentation

ALT organelle segmentation

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Lippincott-Schwartz Lab retweeted
Andy Moore@aaandmoore
22 Sep 2022
Our perspective on endoplasmic reticulum structure has now been published! In this review, we (@cjobara @JLS_Lab) examine the diverse nanoscale ER structures that have been described by light (see below) and electron microscopy. cshperspectives.cshlp.org/co…
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Lippincott-Schwartz Lab retweeted
J Cell Science@J_Cell_Sci
28 Sep 2022
Registration is now open for our 2023 Journal Meeting 'Imaging Cell Dynamics', organised by Erika Holzbaur @ErikaHolzbaur, Jennifer Lippincott-Schwartz @JLS_Lab, Rob Parton @LabParton and Michael Way @DrMichaelWay Find out more and apply to attend at biologists.com/meetings/cell…
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