From emerging therapies to new clinical research, #ASCO2026 brings oncology experts to Chicago, May 29–June 2. Join us for presentations from @nyulangone physicians and researchers.
Check out the full list of our presenters: bit.ly/4fdKFt2
First line oral targeted therapy for advanced non small cell lung cancer, including responses observed in dreaded brain metastatic disease (thanks to the chemistry behind Zongertinib crossing BBB). New study in @NEJMnejm.org/doi/full/10.1056/NE…@JSabari@Perlmutter_CC
Zongertinib (oral TKI) now @US_FDA approved based off #BeamionLung1 in previously treated metastatic NSCLC w/ HER2 :
- 71% ORR w/ 14.1mos mDoR
- mPFS 12.4%
- ≥Gr 3 AEs in less than 20%. Common AEs includied diarrhea and rash
#OncTwitter#MedTwitter
FDA approves zongertinib 120mg po daily for previously treated advanced #HER2 NSCLC. In the phase 1b Beamion-LUNG 1 study @NEJM, RR 71% (42% post ADC), DOR 14.1m, intracranial RR 41%. Main toxicity is diarrhea (56%, 48% grade 1), no ILD.
fda.gov/drugs/resources-info…
Discussing data hot off the press here at #HawaiiLung25.
Dr. Joshua Sabari reviews the latest FDA approval of DatoDXd for our patients with EGFR mNSCLC.