President @LifespanRI, Inventor @DisneyStreaming. Leading advocate for life extension, blockchain, and DeSci. @LifeNoggin,@Vita_DAO,@Gitcoin. Modern Gilgamesh.

Joined April 2009
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Do people want longer lifespans, or just healthspan? Should longevity advocates avoid “life extension,” or lean into it? I just published a preprint exploring this, drawing on mythology & modern data, & what it means for advancing longevity research. zenodo.org/records/19656500
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keithcomito.eth retweeted
In our May 2026 Rejuvenation Roundup, we highlight advances in cellular reprogramming, AI-driven drug discovery, immunotherapy, therapies for cardiovascular disease and Alzheimer’s, and insights into the longevity research landscape. 👉 Read more: lifespan.io/rejuvenation-rou…
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keithcomito.eth retweeted
Will you be in NYC during @Techweek_? Don't miss the @LongevityGL AI x Longevity Summit on June 4-5, bringing together researchers, founders, investors, and more. Agenda and registration: ow.ly/eBQT50Z5JIw
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keithcomito.eth retweeted
In this latest Lifespan Interview, Matthew O'Connor discusses @Cyclarity Therapeutics 's recent successful phase 1 trial demonstrating removal of oxidized cholesterol (7KC) in humans. 👉 Read more: lifespan.io/matthew-oconnor-…
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keithcomito.eth retweeted
The April Rejuvenation Roundup is live! From sedentary zoo penguins aging faster to NAD combinations restoring function in mice and new warnings on senolytics. Learn about progress alongside meaningful risks. lifespan.io/rejuvenation-rou…
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keithcomito.eth retweeted
Replying to @LifespanRI
@LifespanRI CEO and president @KeithComito takes the stage at RejuveAI x Infinita City Longevity Biomarkers Conference, live in Roatan, HN @infinitacity @ProsperaGlobal
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keithcomito.eth retweeted
What were the highs and lows of 2025 in geroscience? What should we expect in 2026? We asked five prominent geroscientists: @prof_horvath, @geochurch, @AndreaBMaier, @mkaeberlein, and Oliver Medvedik. lifespan.io/news/geroscience… By: @ArkadyMazin

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Question: Q: "Where can I find a rejuvenation roadmap with some of the most promising rejuvenation therapies and technologies in development A: Right here, courtesy @KeithComito and his @LifespanRI team: 🧪 🔗lifespan.io/road-maps/the-re… * Special thanks to @KarlPfleger at AgingBiotech.info, "whose therapy database helped to inform this roadmap."
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keithcomito.eth retweeted
As the year comes to a close, we’re building momentum for what’s next. LRI advances the science that targets aging, & the systems that turn breakthroughs into real-world impact. Join us for another year of driving longer, healthier lives for all! lifespan.io/end-of-year-2025…

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Great work by @JellyfishDAO. Now more than ever it is important to paint what positive visions of the future can look like, and its gratifying to see the old “Interviews from the Future” ideas Tim brainstormed with us @LifespanRI back in 2021 now coming to life.
21 Nov 2025
What if our descendants look back at our acceptance of aging the way we look back at medieval medicine? We interviewed them. Dystopian futures are easy to imagine. Optimistic futures take vision and courage to build. VOICES FROM 2099:
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keithcomito.eth retweeted
$100K UNLOCKED! The @PublicLongevity Group is funded! A $5k gift from @RetroBio_ , matched by LRI CEO @KeithComito, pushed us past our full goal. Welcome to the Lifespan Alliance, Retro Bio! Still time until midnight to claim perks: lifespan.io/campaigns/public…
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keithcomito.eth retweeted
Grateful for another $7K for the @PublicLongevity Campaign! Thanks to @quadrascope & LRI board member Andrew Aiello for pushing us closer to our goal of building public trust in longevity. We’re so close, but not there yet. Help us cross the finish line! lifespan.io/campaigns/public…
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keithcomito.eth retweeted
Thank you to LRI Board Chair @paulspiegel of Eclectic Law for matching Gabriel Cian’s $5,000 gift to the Public Longevity Group campaign. Paul supports cross-border collaboration in longevity, including the recent 2060 Longevity Forum. Only days left! Every donation is still matched. ➡️ lifespan.io/campaigns/public…
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keithcomito.eth retweeted
Thank you to Gabriel Cian and the 2060 Foundation for joining the Lifespan Alliance and supporting the @PublicLongevity Group with a generous $5,000 donation. Foundation: 2060.life Forum: forum.2060.life PLG Campaign: lifespan.io/campaigns/public… @CaptainLeads
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keithcomito.eth retweeted
Every dollar now counts twice, thanks to a $25K match from the LRI Board! The @PublicLongevity campaign has passed the halfway mark toward its goal. Your support powers the first public sentiment analysis system for longevity science, helping the field measure and strengthen the impact of advocacy. Public trust is the breakthrough that unlocks all others. Make twice the impact today: lifespan.io/campaigns/public…
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keithcomito.eth retweeted
Big thanks to @iddotlife for backing our @PublicLongevity Group initiative! Help us keep the momentum going 👇 lifespan.io/campaigns/public…
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Just the pleasure copaneling with @KeithComito today (*) Read Keith’s @LifespanRI case for Longevity Advocacy here: 🌟 Building a World Where Freedom From Age-Related Disease is Not Only Desired, but Prioritized⚕️ 🔗lifespan.io/advocacy/ (*) linkedin.com/posts/agingdoc_…
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keithcomito.eth retweeted
First milestone reached! Our @PublicLongevity Group campaign has passed 30% of our goal, thanks to a generous $25k donation from AgingBiotech.info & @KarlPfleger. Learn more & add your support here: lifespan.io/campaigns/public…
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keithcomito.eth retweeted
Thank you to @OpenCuresOrg for supporting our @PublicLongevity Group crowdfunding campaign, with a donation at the 1k (Founder’s Circle) level! Support the campaign today to help us pave the way for longer, healthier lives for all: lifespan.io/campaigns/public…
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keithcomito.eth retweeted
We’re live! The Public Longevity Group campaign has launched. @PublicLongevity, incubated by @LifespanRI , is building the first data-driven cultural intelligence system to track sentiment, test narratives & build public trust. Learn more 👇 lifespan.io/campaigns/public…
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