Neuroscientist studying brain aging and disease leading a lab filled with incredible scientists at the @hscrb department. •Asian food enthusiast.

Joined March 2019
4 Photos and videos
Pinned Tweet
29 Jan 2022
Hot off the press from our lab! Proud to share with you our latest work by Ximerakis et al. where we look at the effects of heterochronic parabiosis in the aging brain and show changes in the transcriptomic profile of some of your *favorite* cell types. 🧠 doi.org/10.1101/2022.01.27.4…
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What are the latest strategies to reverse the effects of aging on brain function? What drives tissue regeneration in the skin and eye, and how can we harness it to treat age-related disease? Join #NYSCF2025 to find out! Advance registration closes 3/14: conference.nyscf.org/registr…
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We are excited to welcome our 2023 NYSCF - Druckenmiller Fellows: @AnuHemalatha (@YaleGenetics), Kentaro Iwasawa (@CincyChildrens), Brian J. Joseph (@Columbia), Kaylee Wells (@Harvard), and Jiajie Xu (@MassGeneralNews)! nyscf.org/programs/extramura…
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13 Jun 2023
@alviratyagi , a 2nd year undergrad in our lab, recently attended the Northeast Regional Meeting of the Society for Developmental Biology (NESDB) with Kaylee Wells her postdoc mentor. Alvira presented her work on the potential role of the protein GDF11 on myelination during aging
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13 Jun 2023
We are so proud of you @alviratyagi !! Great job on both the poster and talk. #Rubinlab #scientist #harvardcollege #undergrads
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15 May 2023
Congratulations to one of our most talented and hardworking RAs in the lab. We wish you all the best Sabrina and look forward to your future career in science!! A prestigious award for a truly brilliant student. We are extremely proud of you @sabrina_ghosh 👏🏻#gatesscholar
15 May 2023
.@sabrina_ghosh, research asst in the @LeeRubinLab, has received a prestigious Gates Cambridge Scholarship and will be starting her PhD at @Cambridge_Uni this fall. Congratulations Sabrina! bu.edu/articles/2023/young-a…
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12 May 2023
Congratulations to our undergrad in the lab @riomclellan on her terrific work in the lab and for winning multiple prestigious awards for her thesis! Bravo 👏🏻👏🏻👏🏻 Rio will be graduating this May from Harvard College and will be pursuing graduate school. Congrats Rio!
A HUGE❗️ congrats to @riomclellan on her undergrad thesis being awarded both the John E. Dowling Thesis Prize AND Hoopes Prize for oustanding research!!! (this thesis was as long as my PhD thesis lol). Work conducted in @LeeRubinLab and @HSCRB! mcb.harvard.edu/department/n…
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Lee Rubin retweeted
22 Dec 2022
New research from @LeeRubinLab in @stemcellreports opens up new avenues for studying inflammatory responses and their regulation in human #astrocytes and serves as a platform to identify therapeutic drugs for #Schizophrenia. cell.com/stem-cell-reports/f…
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10 Mar 2023
Congratulations to @methxim and Kristina for all of their hard work in this paper! 👏🏻 And of course to the rest of the lab for their support and time in pushing this paper out. 👏🏻 We now have more insights into the aging brain and hope to bring more to the field (1/2)
Excited to see this in @NatureAging. We profiled mouse brains following parabiosis to identify changes involved in the rejuvenation & aging acceleration driven by blood factors. Congrats to @LeeRubinlab @jzlevin AvivRegev AmyWagers @HSCRB @BroadInstitute | nature.com/articles/s43587-0…
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10 Mar 2023
(2/2) With our ongoing studies in the lab looking into the changes we observe in this model. #aging #science #parabiosis
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10 Mar 2023
Extremely proud of this publication which is a highly collaborative work from our lab and other groups, hot off the press! 🔥 We show that heterochronic parabiosis causes dynamic transcriptional changes across different cell types. rdcu.be/c7guG #science #aging

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Congratulations to @CescoLime 👏🏻for this publication hot off the press! This differentiation paper shows how to generate lower induced motor neurons (liMoNes/liMNs). Find out more in the paper here: cell.com/cell-reports/pdf/S2… #stemcells #science

3 Jan 2023
New in @CellReports: A new protocol to generate spinal motor neurons from hundreds of #stemcell lines and analyze #gene expression at a single cell level, in a pooled fashion and in parallel. cell.com/cell-reports/fullte…
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Congratulations @CescoLime and @MordesLab on this review!
7 Nov 2022
Recently published in @FrontiersIn: Pluripotent #stemcell strategies for rebuilding the human brain @CescoLime @MordesLab frontiersin.org/articles/10.…
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12 Feb 2022
📢 We have a postdoctoral fellow position available within the skeletal muscle group in our lab at Harvard University. A thorough understanding of satellite cell biology and skeletal muscle regeneration is required. Please send a research statement and CV to lee_rubin@harvard.edu
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12 Feb 2022
(2/2) Experience in mouse and human skeletal muscle cell culture and cell transplant into a variety of mouse models is desirable. #sciencejob #postdocopening #ScienceTwitter
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29 Jan 2022
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Excited to be a part of this awesome team! Here’s some of what I’ve been up to with @LeeRubinLab: Heterochronic #parabiosis reprograms the mouse brain transcriptome by shifting #aging signatures in multiple cell types What can parabiosis do for you? biorxiv.org/content/10.1101/…
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29 Jan 2022
Hot off the press from our lab! Proud to share with you our latest work by Ximerakis et al. where we look at the effects of heterochronic parabiosis in the aging brain and show changes in the transcriptomic profile of some of your *favorite* cell types. 🧠 doi.org/10.1101/2022.01.27.4…
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29 Jan 2022
@methxim @rmgiadone Bravo to the team! Not everyone is tagged so please tag any co-authors you might know have a Twitter account. Happy reading to all!
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29 Jan 2022
Most of all, we thank ALL of our collaborators for their continuous support in this study. The value of teamwork is truly remarkable especially when trying to untangle highly complex questions about the aging brain. 🧠🤔
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