We are honored to see our @CD_AACR paper on #Glycosylation of #breast #circulating #tumor cell clusters discussed in the Spotlight Commentary by Nicola Aceto @CR_AACR. Thanks to the Liu Cluster hero @DNurmaa who did the work @LurieCancer @NUFeinbergMed. doi.org/10.1158/2159-8290.CD…

“We can cure primary tumors by surgery or radiation. However, when tumor cells start spreading from one place to another, they can get out of control. A lot of times it is devastating and incurable,” Huiping Liu, MD, PhD (@LiuCluster), said. “It’s a very significant problem in the clinic and also affects patient outcomes and survival time.” news.feinberg.northwestern.e… @NUfeinbergmed #BreastCancer #CirculatingTumorCells #DPCells

Shout out to @LiuCluster who was co-author of a study published in @ScienceTM on how a group of cancer cells circulating the bloodstream may play a bigger role in breast cancer progression. Read Here: ow.ly/CPJ850YMKut

AI is a big theme at #AACR26, looking forward to co-chairing (w Dr. John Tainer) Minisymposium on #AI and #drugdevelopment #drugresistance #cancerstemness #metabolism #CTC Today 2:30-4:30 at room 28 (upper level) @AACR 7 presenters @UTMDAnderson @LurieCancer @NUFeinbergMed ...

Congrats to our newest PhD, Dr. Hannah Almubarak @LurieCancer @NorthwesternU who presented a talk on evIgG and a poster at #AAEV2025 @UUtah @AAEV_org reconnecting with @rkalluriMDPhD @KeChengLab Drs. Louise Laurent, Stephen Gould, Kate McAndrews, Fei Liu, and many friends

Thanks for the inspiring lightning talks brought by Brian Ivan Molina Diaz, Zachary Franklin Greenberg, Elizabeth Wang, Sichen Zhang, Hannah Almubarak, Junlang Li and Xiao Cheng!

We are delighted to celebrate the election of our esteemed colleague, Dr. Joe Bass, @JoeBass91471540 to the @theNAMedicine. This honor recognizes his outstanding contributions to the field of Endocrinology, Metabolism, and Molecular Medicine, and his pioneering research elucidating the critical links between the body’s circadian rhythms and metabolic regulation. Dr. Bass’s groundbreaking work has revealed how disruptions in the circadian system contribute to metabolic diseases such as diabetes and obesity. This election represents a well-deserved and long-overdue recognition of Dr. Bass’s exceptional scientific achievements and his profound impact on the field. Congratulations, Joe, on this remarkable and richly merited honor. @NU_BMG_SQE @NUFeinbergMed @theNASciences

An unexpected discovery by Lurie Cancer Center member and #CZBiohubChicago President @ShanaOKelley may inform the development of new mutation-specific therapeutic strategies for treating mutant #KRAS-driven cancers, according to findings in @nchembio news.feinberg.northwestern.e…

Our deputy director, Maha Hussain, in my office showing me the Lifetime Achievement Award she got from the PCF for her remarkable clinical research that has transformed the prostate cancer field, led to several FDA approvals and prolonged many lives! ⁦@LurieCancer⁩

Congratulations to Joel Mokyr from @NorthwesternU for the Nobel Prize in economics today!

Thrilled to celebrate @NorthwesternU’s Joel Mokyr, winner of the 2025 @NobelPrize in Economic Sciences for uncovering how technological progress drives sustained growth. Congrats, Joel & go CATs! news.northwestern.edu/storie… @NU_BMG_SQE @NUFeinbergMed @theNASciences @ScienceMagazine @Nature

This is intriguing work coming from @LurieCancer, highlighting critical cellular dynamics that could be pivotal in addressing metastasis in #breastcancer. With cancer cells leveraging immune cell interactions for spread, what implications does this have for developing targeted therapies? For more in-depth, personalized insights on similar topics in #Medicine and #CancerResearch, check out sciqst.com. It's the go-to platform for generating comprehensive biomedical reviews tailored to your inquiries.

Can we root out the seeds of metastasis? @LiuCluster & team @NUFeinbergMed identify a rare T cell subset that cluster circulating tumor cells to promote metastasis in breast cancer, then provide a proof-of-concept block using VLA-4 antibody in preclinical models: jci.org/articles/view/193521

Huiping Liu, MD, PhD (@LiuCluster), and team reveal how tumor–immune cell clusters fuel #BreastCancer metastasis in a pair of new studies published in @NatureComms and @jclinicalinvest. tinyurl.com/4ufa6twt

In a pair of studies, investigators from the lab of @LurieCancer's Huiping Liu, MD, PhD, have uncovered how cellular interactions in the bloodstream may be fueling the spread of #breastcancer. news.feinberg.northwestern.e… via @NUFeinbergMed #CTC #BTSM

Double-positive T cells form heterotypic clusters with circulating tumor cells to foster cancer metastasis

Can we root out the seeds of metastasis? ASCI member @LiuCluster & team @NUFeinbergMed identify a rare T cell subset that cluster circulating tumor cells to promote metastasis in breast cancer, then provide a proof-of-concept block using VLA-4 antibody in preclinical models: jci.org/articles/view/193521

Double-positive T cells form heterotypic clusters with circulating tumor cells to foster cancer metastasis @jclinicalinvest @LiuCluster @NUFeinbergMed @LurieCancer 🇺🇸 jci.org/articles/view/193521

Congrats to Dr. David Scholten, PhD who successfully defended his thesis on CTC-DPT clusters, accepted by @jclinicalinvest. What a rewarding moment - celebrate with his family/friends, Cluster mates, and our Chair @nupharm1 @NUFeinbergMed @LurieCancer biorxiv.org/content/10.1101/…

#AACRai25 cochairs Valentina Boeva and Benjamin Haibe-Kains adjourned the AACR Conference on Artificial Intelligence and Machine Learning. We thank all of the chairs—including @MarzyehGhassemi and @BoWang87—for developing an outstanding program. @val_boeva @bhaibeka

Just had the pleasure of being interviewed by @Nature on the rise of AI in digital pathology. With growing workloads and global shortages of pathologists, the field is turning to AI not as a luxury—but as a necessity. Full article: nature.com/articles/d41586-0… In the article, I discuss how recent advances in foundation models like UNI-2 and CONCH are redefining what’s possible in cancer diagnostics. Trained on hundreds of millions of pathology patches, these models go beyond classification: they enable molecular subtyping, caption generation, and even zero-shot inference. But while the hype is real, so are the challenges. Cross-site generalization, lack of external validation, and regulatory hurdles remain major barriers. We must invest in robust benchmarking, multi-institutional trials, and trustworthy model design to ensure AI truly supports—not replaces—clinical judgment. Digital pathology isn’t the future—it’s already here. Let’s make it safe, scalable, and equitable. @UHN_Research @PMResearch_UHN @VectorInst @UofT