#PancreaticCancer Research Lab interested in selective #autophagy, iron, therapeutic resistance, and #proteomics. @DanaFarber, @BrighamWomens, @harvardmed
Joined May 2017
- Tweets 220
- Following 616
- Followers 814
- Likes 1,705
23 Photos and videos
Pinned Tweet
16 Nov 2017
The Mancias Lab @DanaFarber is fighting #PancreaticCancer on #WorldPancreaticCancerDay #WPCD2017 #WPCD #PANCaware #DemandBetter @PanCAN
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Mancias Lab retweeted
1 Aug 2025
Excited to share our latest story @NatureComms. Here, we used quantitative proteomics, metabolomics and in vitro/in vivo CRISPR screens to define mechanisms of resistance to DHODHi in PDAC and propose combinatorial approaches with BCL-XL inhibitors:
nature.com/articles/s41467-0…
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Mancias Lab retweeted
31 Oct 2024
How #autophagy influences the regulation of MHC-I class receptors and regulates #immune evasion of #cancer?
A new role for an autophagy receptor IRGQ in this process with a clinical relevance for the development of liver carcinoma in humans and mice 😊😀
sciencedirect.com/science/ar…
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During the keynote addresses at #AACRpan24, Eileen M. O’Reilly and Joseph D. Mancias discussed how understanding pancreatic cancer’s strengths can help researchers uncover its weaknesses. Learn more on the #AACRBlog: bit.ly/47G1kQ9 @EileenMOReilly @ManciasLab
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Joseph D. Mancias discussed "Targeting Autophagy in Pancreatic Cancer" in a Rising Star Keynote Lecture during the AACR Special Conference on Advances in Pancreatic Cancer Research.
#AACRpan24 @ManciasLab
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Mancias Lab retweeted
6 May 2024
The (almost) full program is now online with an amazing lineup of speakers!
#AACRPan24
@EileenMOReilly @ManciasLab @DrJashDatta @TeresaZimmers @DrHendifar @JanowitzTobias @wantong_yao @MaraShermanLab @KenOliveLab @andrewaguirremd @cjder23 @bryant_kl @pratt_ed @mggoggins @ChristieTowers @Cosimo_Commisso @Chiolaboratory @nada_kalaany and those not on Twitter. See you all in Boston!
aacr.org/meeting/aacr-specia…
@AACR #PancreaticCancer
28 Apr 2024
Abstract submissions are now open for the @AACR special conference on #PancreaticCancer #AACRPan24
Outline of proposed program below:
aacr.org/meeting/aacr-specia…
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Mancias Lab retweeted
29 Sep 2023
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Mancias Lab retweeted
16 Jun 2023
WE ARE HIRING! We are looking for a motivated postdoc to work on a fully-funded project studying the role of iron metabolism in drug resistance in pancreatic cancer. 3 weeks left to apply. Please spread the word.
au.dk/om/stillinger/job/post…
lnkd.in/eNgDM74z
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Mancias Lab retweeted
13 Apr 2023
Our #OpenAccess review on #PancreaticCancer - advances & challenges is now online at @CellCellPress
Many thanks to @CJHPhD @Pasca_Lab & @LyssiotisLab for all the hard work & @jiaying_tan6 for the opportunity.
It’s FREE to read so share widely!
cell.com/cell/fulltext/S0092…
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Mancias Lab retweeted
24 Feb 2023
We are so inspired by patients like Candace and her experience. With a loving and supportive family and the latest treatments at @DanaFarber, Candace is a source of hope for more patients with pancreatic cancer. blog.dana-farber.org/insight…
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Mancias Lab retweeted
12 Jan 2023
Researchers at @DanaFarber and other institutions recently made important discoveries into the recycling system of pancreatic cancer cells, a promising step toward targeted therapies for one of the most challenging cancers. blog.dana-farber.org/insight…
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Mancias Lab retweeted
2 Jan 2023
Pancreatic cancer cells operate a recycling program that would be the envy of any municipality — but the only beneficiaries are the cells themselves. blog.dana-farber.org/insight…
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Mancias Lab retweeted
A cross-country collaboration between former Damon Runyon-Rachleff Innovators @rushika_perera and @ManciasLab uncovered another way that #PancreaticCancer evades targeted therapies – and a new potential therapeutic target: bit.ly/3uQwFgd
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Mancias Lab retweeted
7 Dec 2022
Latest Wolpin-Nowak lab paper on single cell, in situ protein-based characterization of transcriptional subtypes in pancreatic cancer now out in @CR_AACR aacrjournals.org/cancerres/a…
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Mancias Lab retweeted
4 Nov 2022
Now online in @CD_AACR: Targeting UGCG Overcomes Resistance to Lysosomal #Autophagy Inhibition by Vaibhav Jain, David Speicher, @AmaravadiRavi and colleagues @TheWistar @PennCancer aacrjournals.org/cancerdisco…
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Mancias Lab retweeted
Robert Hale's determination in @DanaFarber and the Hale Family's incredible generosity help drive @DanaFarber_Hale closer to a cure for pancreatic cancer.
forbes.com/video/63128816421…
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Mancias Lab retweeted
2 Sep 2022
On the cover!! Thanks @CD_AACR for featuring work from our lab by Miru Ravichandran and @ManciasLab @SantanaCodina on the cover !
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Mancias Lab retweeted
2 Sep 2022
Thanks to @CD_AACR for featuring our stories @ManciasLab and @rushika_perera on the cover of the September issue!
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Mancias Lab retweeted
6 Aug 2022
🚨Job Posting: The @YatrikShahLab & @LyssiotisLab are looking for a postdoc to study the role of iron, O2, & metabolism in erythropoiesis. Opportunities to learn and employ multiple cutting-edge technologies in 2 ~pretty cool labs 😁 DM with interest.
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Mancias Lab retweeted
13 Jul 2022
Happy to share our latest work now out in @nature. At long last, we resolved the structure of the SHOC2-RAS-PP1C complex and integrated this work with deep mutational scanning to comprehensively evaluate #SHOC2 structure and function. 🧵(1/n)
nature.com/articles/s41586-0…
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Mancias Lab retweeted
7 Jul 2022
Two recent preclinical studies highlight the importance of ferritinophagy in pancreatic cancer, with elevation of a ferritinophagy expression signature also predicting poor prognosis in patients with PDAC: aacrjournals.org/cancerdisco… and aacrjournals.org/cancerdisco… #PancSM
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