PTM and cell proliferation lab at the @ICR_London. Tweets are from anyone in the lab :-)

Joined July 2021
3 Photos and videos
Mansfeld Lab retweeted
UK REDOX NETWORK 2025 Meeting at Institute of Cancer Research, London SW7 3RP28 April 2025. Excellent programme coordinated by Olena Rudyk (KCL) and Joerg Mansfeld (ICR). @SFRR_Europe @kingscardio @elsbiomedchem
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Have you ever wondered what H2O2 does in your cells? We are looking a highly motivated #Postdoc to investigate #Redox regulation of #DNAReplication and #DNADamage repair. Our lab is based at the ICR in Chelsea, London, UK. Please apply here: rb.gy/7ddtmh #mansfeldlab

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Mansfeld Lab retweeted
UK REDOX NETWORK Meeting Session 2: Helena Cocheme (Imperial College) introduces Joerg Mansfeld (Institute of Cancer Research) (intranet.sfrr-europe.org/doc……; @SFRR_Europe @SFRRAustralasia @SFRBM @CochemeLab @JuliaVorhauser
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Mansfeld Lab retweeted
13 Dec 2022
We have several postdoc openings! tu-dresden.de/cmcb/biotec/fo… Our interdisciplinary group works on the #Genomics of #DNAdamage and #Mutagenesis using #ComputationalBiology, #MachineLearning and #AI. (details in following tweets)
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Mansfeld Lab retweeted
25 Nov 2022
An extraordinary paper showing an unexpected redox role for BCAT1 in accurate chromosome segregation. There is clearly something important about how redox changes modulate the cell cycle, especially in mitosis. doi.org/10.1016/j.celrep.202…

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Mansfeld Lab retweeted
How does polymerisation activate the ADP-ribosyltransferase tankyrase? We are a few steps closer to the answer: rdcu.be/c0hLX. Congratulations to the team, and thank you to our funders, especially @CRUKresearch @wellcometrust @ICR_London @ListerInstitute!
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Mansfeld Lab retweeted
I am thrilled and honoured to be one of the #ERCStG recipients! So grateful to @ERC_Research, my mentors, colleagues at the @ICR and my family. We will explore the roles of histone acetylation in cancer and will be recruiting soon. erc.europa.eu/news-events/ne…
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Mansfeld Lab retweeted
22 Nov 2022
Many congratulations to Alex Radzishueskaya in our Division who has been awarded an ERC Starting Grant!
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Mansfeld Lab retweeted
Interesting @biorxivpreprint by the group of Ben Cravatt @scrippsresearch with the group of @davidrliu. They use base-editing to assign essentiality to >10,000 cysteines in cancer cell lines. Full post on @joinmastodon @Stephanhacker2@mstdn.science. doi.org/10.1101/2022.11.17.5…

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The @MansfeldLab just returned from the EMBO “Thiol in oxidation in biology” meeting. Super exciting and at a wonderful place. And @JuliaVorhauser won the POSTERPRIZE. Thanks to Bruce Morgan, Haike Antelmann and @dana_reichmann for organising one of the best workshops this year.
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Mansfeld Lab retweeted
11 Aug 2022
The @NerliElisa strikes again! Deterministic and probabilistic fate decisions exist in the same retinal lineage! A tour de force and amazing team effort led and guided by Elisa. She will discuss in more detail, I go on conference and vacation :-). biorxiv.org/content/10.1101/…
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Mansfeld Lab retweeted
12 Aug 2022
Professor Chris Bakal's lab (@BakalLabICR) show that #Melanoma #SkinCancer cells harness ARHGEF9 - a gene usually used by growing nerves - to drill through surrounding tissues and escape from their immediate area. Read more: icr.ac.uk/news-archive/skin-…

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Our article on a ROS-dependent regulation of CDK2 (doi.org/10.1016/j.devcel.202…) has just been recommended on @FacultyOpinions facultyopinions.com/article/… Thanks verybody @MansfeldLab & @BIOTEC_TUD & @ICR_London to make this a worthwile and exciting endeavour.
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Mansfeld Lab retweeted
27 Jul 2022
📢 NEWS: ICR scientists (@MansfeldLab) have discovered how naturally occurring, unstable molecules, known as free radicals, can directly regulate a key protein for cell division called CDK2, opening up a potential new way to target #Cancer 👇 icr.ac.uk/news-features/news…

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Mansfeld Lab retweeted
📢 Hot off the press 📢 🧬 Ever wonder why some DNA sequences are difficult to replicate? Using reconstituted replisomes we revealed that structure-forming repeats induce robust replication stalling and uncovered structure-specific recovery mechanisms: nature.com/articles/s41467-0…

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Good things come to those who are patient ... started in Dresden @BIOTEC_TUD - finished in London @ICR_London: Our study how ROS promotes proliferation via CDK2 oxidation was just published in @Dev_Cell! :-) doi.org/10.1016/j.devcel.202…
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Very happy to announce that our last woman standing in Dresden successfully defended her PhD! Congratulations Dr. Kristyna Judasova!!!🥳🥳🥳
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Mansfeld Lab retweeted
Dr Alexis Barr is a Cancer Research UK Career Development Fellow in the Institute of Clinical Sciences! Find out about Alexis' research on quiescence and interests outside of work on the social media card below and in our profile series booklet: buff.ly/3vQ5fJm
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Mansfeld Lab retweeted
If you are a PhD student or a postdoc at a Ukrainian university/institute on a topic related to computational or experimental proteomics and you would be interested in a paid internship in my lab @ICR (for ~up to 6 months or more if possible), please email me.
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