UK REDOX NETWORK 2025 Meeting at Institute of Cancer Research, London SW7 3RP28 April 2025. Excellent programme coordinated by Olena Rudyk (KCL) and Joerg Mansfeld (ICR). @SFRR_Europe@kingscardio @elsbiomedchem
Have you ever wondered what H2O2 does in your cells? We are looking a highly motivated #Postdoc to investigate #Redox regulation of #DNAReplication and #DNADamage repair. Our lab is based at the ICR in Chelsea, London, UK. Please apply here: rb.gy/7ddtmh#mansfeldlab
An extraordinary paper showing an unexpected redox role for BCAT1 in accurate chromosome segregation. There is clearly something important about how redox changes modulate the cell cycle, especially in mitosis. doi.org/10.1016/j.celrep.202…
I am thrilled and honoured to be one of the #ERCStG recipients! So grateful to @ERC_Research, my mentors, colleagues at the @ICR and my family. We will explore the roles of histone acetylation in cancer and will be recruiting soon.
erc.europa.eu/news-events/ne…
The @MansfeldLab just returned from the EMBO “Thiol in oxidation in biology” meeting. Super exciting and at a wonderful place. And @JuliaVorhauser won the POSTERPRIZE. Thanks to Bruce Morgan, Haike Antelmann and @dana_reichmann for organising one of the best workshops this year.
The @NerliElisa strikes again! Deterministic and probabilistic fate decisions exist in the same retinal lineage! A tour de force and amazing team effort led and guided by Elisa. She will discuss in more detail, I go on conference and vacation :-). biorxiv.org/content/10.1101/…
Professor Chris Bakal's lab (@BakalLabICR) show that #Melanoma#SkinCancer cells harness ARHGEF9 - a gene usually used by growing nerves - to drill through surrounding tissues and escape from their immediate area.
Read more: icr.ac.uk/news-archive/skin-…
📢 NEWS: ICR scientists (@MansfeldLab) have discovered how naturally occurring, unstable molecules, known as free radicals, can directly regulate a key protein for cell division called CDK2, opening up a potential new way to target #Cancer 👇
icr.ac.uk/news-features/news…
📢 Hot off the press 📢
🧬 Ever wonder why some DNA sequences are difficult to replicate?
Using reconstituted replisomes we revealed that structure-forming repeats induce robust replication stalling and uncovered structure-specific recovery mechanisms:
nature.com/articles/s41467-0…
Dr Alexis Barr is a Cancer Research UK Career Development Fellow in the Institute of Clinical Sciences!
Find out about Alexis' research on quiescence and interests outside of work on the social media card below and in our profile series booklet: buff.ly/3vQ5fJm
If you are a PhD student or a postdoc at a Ukrainian university/institute on a topic related to computational or experimental proteomics and you would be interested in a paid internship in my lab @ICR (for ~up to 6 months or more if possible), please email me.