Postdoc @HarvardMed. CryoEM and anything chromatin or transcription. views are my own
Joined December 2019
- Tweets 102
- Following 107
- Followers 164
- Likes 1,129
Photos and videos
Jon Markert retweeted
15 Mar 2025
I’m very happy to share our latest work on the ParABS system. We investigated the dynamic interaction between the ATPase ParA and the CTPase ParB mediating chromosome segregation in Myxococcus xanthus. I would like to thank all the people involved.
15 Mar 2025
Molecular basis of ParA ATPase activation by the CTPase ParB during bacterial chromosome segregation biorxiv.org/content/10.1101/… #biorxiv_micrbio
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13 Dec 2024
Our work providing the mechanistic basis for SETD2 function is finally out! We demonstrate SETD2 requires active transcription to facilitate H3K36me3 deposition!
12 Dec 2024
Ever wondered how transcription choreographs histone modifications? Our work reveals the basis of co-transcriptional H3K36me3 by SETD2. We visualize how a histone writer coordinates with the transcription machinery! This is the magnus opus of @MarkertJon tinyurl.com/setd2
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Jon Markert retweeted
14 Nov 2024
Excited that our work on transcription-coupled DNA repair is now published @CellCellPress! We recapitulated TC-NER in Xenopus egg extract and identified STK19 as a core repair factor that couples stalled Pol II to TFIIH. 🧬🐸
➡️ cell.com/cell/fulltext/S0092…
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Jon Markert retweeted
19 May 2024
Hiring! Seeking motivated postdocs, technicians, and graduate students for our new lab at the University of Miami Miller School of Medicine. Dive into protein chemistry and chemical proteomics to explore cancer and aging. #ZwangLab #UMiami #Research
zawanglab.com/
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Jon Markert retweeted
14 May 2024
I am happy to share that I will be starting an assistant professor position at the Van Andel Research Institute @VAInstitute in the Department of Neurodegenerative Science. My lab is opening in July, and I am currently hiring: vai.wd1.myworkdayjobs.com/en… and vai.wd1.myworkdayjobs.com/en…
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Jon Markert retweeted
2 Mar 2024
biology methods for understanding protein post-translational modifications in cancer & aging. Excited for this new journey! Looking to hire passionate postdocs, technicians, and grad students. Join us! [Main Webpage: zawanglab.com/] #research #Careers
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Jon Markert retweeted
8 Dec 2023
Our paper on the structure of the complete Rpd3S-nucleosome complex is now out in Nat Comm: rdcu.be/ds6k1. Congrats to @MarkertJon and co-corresponding author @seyvos ! This is the second HDAC-nucleosome structure from Jon this year. Amazing!
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Jon Markert retweeted
4 Aug 2023
Our story on the complete Rpd3S-nucleosome complex is now online on Biorxiv: biorxiv.org/content/10.1101/…
We visualize the S. cerevisiae Rpd3S complex bound to a nucleosome including the "evasive" Ume1 subunit!
Congrats, @MarkertJon! Thank you @seyvos for a great collaboration.
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Our latest publication reports the cryo-EM structures of the human Polα-Primase DNA elongation complexes - rdcu.be/c96yY A Lim lab X Tahirov lab collaboration led by @QixiangHe and Andrey. Thank you, @sarakosman & @NatureSMB, for working with us! Please RT to share! 1/4
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Jon Markert retweeted
30 Mar 2023
Mechanism of histone H2B monoubiquitination by Bre1 biorxiv.org/content/10.1101/…
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Jon Markert retweeted
29 Mar 2023
Congratulations to Farnung lab PhD Candidate Felix Steinruecke! He has been selected to receive a 2023 NSF Graduate Research Fellowship. Amazing!
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Jon Markert retweeted
24 Mar 2023
So excited to share that my thesis work is out now at @MolecularCell! Karen @AdelmanLab and I show that U1 snRNP increases RNA Pol II elongation rate within AT-rich introns, thereby reducing the likelihood of Pol II termination or arrest. Highlights below! authors.elsevier.com/c/1gobY…
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Jon Markert retweeted
21 Mar 2023
Binding to nucleosome poises SIRT6 for histone H3 de-acetylation biorxiv.org/cgi/content/shor…
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Jon Markert retweeted
19 Mar 2023
I’m excited to share a new manuscript on Sirtuin6-nucleosome structure, a result of a great collaboration between @PetersonLab, Song Tan’s, and @valendraica labs. /1
biorxiv.org/content/10.1101/…
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Jon Markert retweeted
19 Mar 2023
Exciting complimentary nucleosome-SIRT6 work by @valendraica, Song Tan and Craig Peterson labs: biorxiv.org/content/10.1101/… Interesting differences in H2A dynamics in the absence of NAD vs. our catalytically poised state. Our story: pubs.acs.org/doi/10.1021/jac…
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27 Jan 2023
Congrats to Shawn and team!! First we learn from @LugerLab about eukaryotic histones…then virus…and now…bacteria!?!? What next???
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Jon Markert retweeted
6 Jan 2023
The Effects of Histone H2B ubiquitylations and H3K79me3 on Transcription Elongation biorxiv.org/cgi/content/shor… #bioRxiv
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Jon Markert retweeted
2 Dec 2022
The Kurumizaka ERATO project is organizing a virtual International Symposium titled "Chromatin Architecture: Structure and Function" on Jan. 24-25, 2023. Registration is open now! Deadline for abstracts submission for posters is Jan. 9, 2023. Check it out! bit.ly/3XPvQS8
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Jon Markert retweeted
23 Nov 2022
Mechanism of RanGTP priming the release of H2A-H2B from Kap114 and Importin-9 biorxiv.org/cgi/content/shor…
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