Postdoctoral Fellow in the Moser Lab at @KISNeuro | studying cortical networks in the developing brain

Joined November 2020
21 Photos and videos
Matteo Guardamagna retweeted
Thrilled to share this study is now out - thanks to the thoughtful and constructive reviewers for strengthening the paper! And huge congrats to first author Dr. Celine Drieu and amazing team of @ziyizhu15 @saraveau, joy wang, Aaron Wang, and Kylie Fuller rdcu.be/eeeBa

1/ A century ago, Tolman showed that meaningful learning can occur even without apparent performance improvements. What is the neural basis of this distinction between learning something vs learning to perform? We tackle this in a new manuscript 🔥 🐭🔬📰 biorxiv.org/cgi/content/shor…
7
16
63
8,199
Matteo Guardamagna retweeted
17 Mar 2025
Here's a 16-hour timelapse of an embryo building a central nervous system so 23 years from now it can sell b2b SAAS
513
4,846
59,494
3,612,754
Matteo Guardamagna retweeted
Very happy to share this new review in Neuron on the function of spontaneous activity across scales and species. Amazing intellectual effort by Anastasia Dimakou who found meaning in a large and confusing literature. Humbly: a real gem! sciencedirect.com/science/ar…

1
6
17
1,647
Matteo Guardamagna retweeted
Check out my preprint on hippocampal ripple diversity, with @_vitorLdS and David Dupret at @MRCBNDU, where we reveal that distinct CA1 laminar profiles of ripples are associated with different reactivation dynamics: doi.org/10.1101/2025.03.11.6… #hippocampus

2
8
27
2,373
Matteo Guardamagna retweeted
A great article from SWC on our neural data analysis technique (now accepted into ICLR). More updates to come soon...plus will be @CosyneMeeting presenting this too!
13 Mar 2025
How does the brain represent imagined locations? Researchers at SWC, @GatsbyUCL and @UCL developed SIMPL, a method to refine neural tuning curves by correcting distortions from imagined locations—sharpening our view of place cell activity. Read more: sainsburywellcome.org/web/bl…
5
29
2,307
Matteo Guardamagna retweeted
11 Mar 2025
Today marks the beginning of OpenRxiv, which replaces bioRxiv and medRxiv, the world's largest preprint platform for life and medical science @openrxiv
18
501
1,735
173,869
Matteo Guardamagna retweeted
🚨 New lab paper!🚨 Dream study of mine for 20 yrs not possible until now thanks to NIH 🧠 funding & 1st-author lead @m_seeber We tracked hippocampal activity as people walked memory-guided paths & imagined them again. Did brain patterns reappear?🧵👇 nature.com/articles/s41562-0…

11
56
211
16,093
Matteo Guardamagna retweeted
9 Mar 2025
Dynamic regulation of cortical interneuron wiring "In this review, we focus on the latest progress in our understanding of the processes that regulate interneuron wiring adaptability." doi.org/10.1016/j.conb.2025.…
36
155
9,626
Matteo Guardamagna retweeted
🚀New paper out! Can somatosensory maps be reshaped before birth? We reveal a critical embryonic window where prenatal mystacial whiskers deprivation reorganizes facial maps, expanding upper lip representation, refining map resolution & enhancing function. nature.com/articles/s41467-0…
5
15
56
5,295
Matteo Guardamagna retweeted
I am very proud to announce that my PhD paper finally came out in Cell! In this *very* collaborative study, we develop and release a deep-learning approach to predict neuron type identity from their electrical signature. doi.org/10.1016/j.cell.2025.… 1/16 🧵

Our “Neuro-AI” paper has just been published in Cell. It describes a new deep learning-based classifier for identifying different cell types in Neuropixels recordings: doi.org/10.1016/j.cell.2025.…
4
24
91
7,028
Matteo Guardamagna retweeted
27 Feb 2025
Virtual reality rewrites the rules of the swarm. Our latest paper in @ScienceMagazine @maxplanckpress @UniKonstanz @CBehav science.org/doi/10.1126/scie…
5
33
114
8,326
Matteo Guardamagna retweeted
New from the lab!! 👉🏼authors.elsevier.com/a/1kgT4… 📝@NeuroCellPress We discovered that genetically-defined neuron types in the hippocampus form unique manifolds! Dual color imaging, chemogenetics and topological analysis all at once! With @Julio_EI @JuanPQuinta @JAlGallego
11
58
170
16,069
Matteo Guardamagna retweeted
24 Feb 2025
The seemingly diverse and random statistics of place cell firing fields in large and small environments; in 1d, 2d, and 3d; in bats and rodents are explained by a remarkably simple mathematical model. With @nischmainali and @Rava_daSilveira: doi.org/10.1016/j.neuron.202… @ELSCbrain #KiloNeurons @ERC_Research

Our(@yoramburak,@Rava_daSilveira) work on mathematical principles underlying place maps in Hippocampus is out @NeuroCellPress! We unify various experimental findings under one model that holds across species, dimensionalities & spatial scale. Link: cell.com/neuron/fulltext/S08… 🧵👇
2
10
23
2,129
Matteo Guardamagna retweeted
Sam Gershman writes beautifully about how theory-free neuroscience prevents the field from reaching its promise. Beautiful and true. Most folks do not test hypotheses. Running a NHST does not a hypothesis make. thetransmitter.org/theoretic…
12
53
256
17,902
Matteo Guardamagna retweeted
1/ Our paper appeared in @Nature today! nature.com/articles/s41586-0… @FieteGroup @KhonaMikail. Explains emergence of multiple grid cell modules, w/ excellent match to data! Novel mechanism for applying across vast systems from development to ecosystems. 🧵👇
2
47
192
17,801
Matteo Guardamagna retweeted
18 Feb 2025
Want to hear more about hippocampus-to-cortex feedback circuit? Our paper with the Basu lab is out in Nat Neuro! rdcu.be/eak1k . Well done Tanvi Butola!

1
7
16
1,220
Matteo Guardamagna retweeted
The developmental emergence of reliable cortical representations | Nature Neuroscience nature.com/articles/s41593-0…

19
62
5,271