🚨Preprint alert! STRAIGHT-IN Dual allows the generation of homogenous genetically-modified hiPSCs ▪️ Done in 1 week with ~100% efficiency ▪️ Markerless and near-scarless approach performed in >10days in a single-well ▪️ Carrying not one but two (single-copy) payloads See🧵below!

Could the folding of synthetic gene circuits in 3D shape how genes are expressed? Today @ScienceMagazine we report on the role of gene syntax in shaping feedback between transcriptional activity and genome folding for advanced circuit design🧵 (1/n)

Our STRAIGHT-IN Dual platform is officially out at @natBME 🔥🚀 A big step forward for programmable stem cell engineering — faster, cleaner, and more versatile. Link📰: nature.com/articles/s41551-0… Don’t miss the 🧵 from the one and only @GallowayLabMIT breaking it all down 👇

🚨We have updated our STRAIGHT-IN Dual preprint! 🧵with all the details in the comments (1/n) Link: biorxiv.org/content/10.1101/… @GallowayLabMIT @nbwang22 @BenBlakeleyJ @annionna

How do cells transit from fate to fate? Quietly. @MITChemE

New career goal unlocked: ✅ Attending the #SynBio24 conference with my twin brother @marcblanch94. Thanks @GallowayLabMIT @billerbeck_s @ProfTomEllis and Yasunori for the amazing program and opportunity to present my last preprint STRAIGHT-IN Dual ⬇️ biorxiv.org/content/10.1101/…

artxscience 2024 #5 - reNEW Vote for picture #5. ⁦@BenBlakeleyJ⁩ renew.science/artxscience/ar…

What characteristics should an MPS have to be useful for modeling human phenotypes? In this review, we (mainly @dennisnahon & @MoerkensRenee) created a reference for quantifiable 'design' and 'emerging' MPS features to compare to real human settings. nature.com/articles/s41551-0…

Super thrilled to be part of the reNEW #ARTxSCIENCE competition! Choose your favorite image (obviously mine 😉) showing some exciting new work happening with another postdoc and myself! renew.science/artxscience/#a… #LUMC @MummeryLab #cardioid #confocal #stemcell #cardiac

Extremely happy to see the protocol manuscript for the STRAIGHT-IN platform out online and featured as protocol of the week @NatureProtocols.

Join Professor Christine Mummery (@MummeryLab), #reNEW Leiden @LUMC_Leiden, for a panel discussion at #ISSCR2024 on 'Use of Standards for Stem Cells in Non-Clinical Research' on Fri 12 July, 1.30pm-3.00pm CEST in Hall G2, Level 2.

Happy to see our work highlighted at The Scientist magazine. Targeted Gene Integration for High-Throughput Applications the-scientist.com/targeted-g…

Kicking off the last session of Day 1 #ISSCRCincy is @MummeryLab with a fantastic update on her work on hpsc-derived cardiovascular tissue to study disease. @ISSCR

We are pushing stem cell research further than ever before. Meet Professor Christine Mummery. Her work focuses on understanding cardiovascular development and disease mechanisms.​ All reNEW researchers are leaders within their field, with a strong track record of scientific excellence. Together, they work to turn their research into real therapies that improve the health of people around the world. See full video: renew.science/principal_inve… @GlobalLumc @MummeryLab @MCRI_for_kids @UCPH_Research #stemcellresearch #stemcelltherapies #cardiovasculardevelopment

Congratulations to postdoc Ben Johnson, from the Richard Davis and @MummeryLab at reNEW Leiden for receiving a prestigious Marie Curie fellowship. Ben will use the fellowship to develop a stem cell based model for myocardial infarctions. Read more: renew.science/stories/marie-…

Delighted to welcome Albert Blanch Asensio @A_BlanchAsensio as a visiting student with our lab! Albert pioneered STRAIGHT-IN with Richard Davis and @MummeryLab. We're excited to build circuits in these landing pad iPSC lines! tinyurl.com/snhjesjw

🧐 #MeetTheSpeaker! 🔬 @MummeryLab @LUMC_Leiden explores the potential of #iPSCs in disease modeling. From mimicking patient mutations to screening for drugs, the goal is to create a population study for personalized medicine. youtu.be/a13QH7CM-pc

Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes dlvr.it/T18sgJ

Thrilled to be awarded the NWO-XS grant to generate an inducible heart attack stem cell model in a fantastic lab! ⁦@MummeryLab⁩ ⁦@reNEW_Global⁩ linkedin.com/posts/novo-nord…

The true #vascular meets #cardiac: it's going to be an awesome conference! Looking forward to it. Mark your calendars!🗓️ #Cardiovascular @UofT_LMP @bme_uoft @UHN_Research @TGHRI_UHN @vascularbiology