Joined February 2022
Photos and videos
Having a great first experience at #PEQG26 ! So many cool projects and friendly people. Come visit me at my poster tomorrow to talk about TEs and SVs!
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Nathan Mathieu retweeted
Long reads carry multiple small vars and SVs and their phasing. LongcallD is the only caller that tightly integrates germline/mosaic small/structural vars/MEIs and their phasing in a single C program. One command line to get competitive small variant calls and better SVs.
New preprint on longcallD: a unified framework for joint calling and phasing of small, structural and mosaic variants from long reads. Improved SV calling and competitive small variant calling. Supervised by @lh3lh3 , co-work with @QianAlvinQin1, @wwliao88 and @irahall9.
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PatchWorkPlot: simultaneous visualization of local alignments across multiple sequences academic.oup.com/bioinformat… 🧬🖥️🧪
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Here's the short story of how I got into flower bioengineering! 🌹🧬✨ This was my application for the @osvllc fellowship (they're taking applications now!)
Since you guys liked my last flower bioengineering poster... here's another!
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Now published in gigascience: academic.oup.com/gigascience…. Key messages: SVs are highly enriched in low-complexity/tandem-repeat regions and are harder to call. They behave differently from transposon insertions. Always stratify if you study SVs.
30 Sep 2025
Do you know ~60% of human SVs fall in ~1% of GRCh38? See our new preprint: arxiv.org/abs/2509.23057 and the companion blog post on how we started this project and longdust: lh3.github.io/2025/09/29/on-…. Work with @QianAlvinQin1
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Another great collaboration with @sedlazeck lab published at last. We amplify and long read sequence human brain single cell genomes, and provide insights into transposon-related structural changes. Caveats of course apply including small sample size. nature.com/articles/s42003-0…
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Interested in how we can leverage all this fancy new omics data to improve plants for productivity under climate change? @jnbserres and I share our ideas in this new review: nature.com/articles/s41588-0…
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20 Dec 2023
This week in Nature: One year. Ten stories - 10 people who helped shape science in 2023 Browse the full issue: nature.com/nature/volumes/62…
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15 Dec 2023
Text editor recommendation for beginners: neovim lunarvim text editor recommendations for experts: neovim lunarvim 😁
15 Dec 2023
Alright, you want some Text Editor Recommendations for Beginners? I've got some for you 👇
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Local registration for the 2024 round of my Statistical Rethinking course has begun. I'll open up registration on Sunday 3 December. Registration link will appear on the course github page: github.com/rmcelreath/stat_r…
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28 Nov 2023
How Git works under the HOOD? We've made a video about this topic (Find link at the end). To begin with, it's essential to identify where our code is stored. The common assumption is that there are only two locations - one on a remote server like Github and the other on our local machine. However, this isn't entirely accurate. Git maintains three local storages on our machine, which means that our code can be found in four places: - Working directory: where we edit files - Staging area: a temporary location where files are kept for the next commit - Local repository: contains the code that has been committed - Remote repository: the remote server that stores the code Most Git commands primarily move files between these four locations. Over to you: Do you know which storage location the "git tag" command operates on? This command can add annotations to a commit. Watch the video here: youtu.be/e9lnsKot_SQ
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Happy Transposon Day 2023! Today is the 121st birthday of Barbara McClintock, founder of the #transposon field and Nobel laureate. Please celebrate with us by using the hashtag #TransposonDay2023. How has Barbara McClintock or her work influenced you? mobilednajournal.biomedcentr…
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Nathan Mathieu retweeted
29 May 2023
Corn plants producing betalain, the red pigment found in beets.
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UV reflectance in crop remote sensing: Assessing the current state of knowledge and extending research with strawberry cultivars. biorxiv.org/cgi/content/shor… #biorxiv_plants

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3 May 2023
ChatGPT just dropped their most powerful tool yet 🤯 It's called the Code Interpreter. From creating charts to basic video editing to converting files, it does it all. Here are some of the craziest things it is capable of 🧵
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African rice (Oryza glaberrima) genomic introgressions impacting upon panicle architecture in Asian rice (O. sativa) lead to the ... biorxiv.org/cgi/content/shor… #biorxiv_plants

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