Exciting findings from @NasserWasim's lab: Targeting FOXM1 with small molecule inhibitors reshapes the immune response and sensitizes chemo-resistant small cell lung cancer cells to treatment.
Read here: sciencedirect.com/science/ar…
Congratulations to Dr. Nasser Lab @NasserWasim on publishing manuscript “Targeting FOXM1 reshapes antitumor immunity to attenuate small cell lung cancer progression” in Cancer Letters! pubmed.ncbi.nlm.nih.gov/4127… Md Arafat Khan is the first author
Thank you to @AparGanti for taking the time to discuss lung cancer in Nebraska and who is eligible for CT screening. Early detection saves lives!
#LungCancerAwarenessMonth
Our talented Biochemistry & Molecular Biology students created a new video showcasing the energy, curiosity, and community that make the BMB Department truly special.
👉 Watch here: youtube.com/watch?v=YsZuZNhk…
Recent article by @Dr_JSantamaria, @NasserWasim, and Dr. Surinder Batra in @AnnSurgOncol shows that pre-treatment tumor collagen is associated with TNBC resistance to chemo-immunotherapy -- potential for predictive biomarkers and targeted treatments! link.springer.com/article/10…
Congratulations to Dr. Batra and Dr. Lakshmanan labs @ImayavarambanL for
the manuscript “ST6GalNAc-I regulates tumor cell sialylation via NECTIN2/MUC5AC-mediated immunosuppression and angiogenesis in
non–small cell lung cancer” published in JCI!
jci.org/articles/view/186863
Congratulations to Dr. Nasser Lab @NasserWasim on publishing manuscript “Mucin5AC promotes breast cancer brain metastasis through cMET/CD44v6” in Clinical Cancer Research! Shailendra Maurya is the first author
Join us tomorrow for the BMB Annual Research Symposium! We have some great speakers lined up, including our Keynote Speaker, Dr. Holly Van Remmen who will share her work on the effect of redox biology on muscles in aging. @unmc_research@UNMCCOM@UNMC_Biochem
Congratulations to Dr. Batra and Dr. Lakshmanan on publishing article “MUC16 promotes triple‑negative breast cancer lung metastasis by modulating RNA‑binding protein ELAVL1/HUR” in BMC Breast Cancer Research
breast-cancer-research.biome…
Sanjib Chaudhary is a first author
A recent @ScienceTM Viewpoint reviews recent developments in #immunotherapy for solid tumors and highlights progress in translational research and clinical practice. scim.ag/1aN
A new detection technique for small-cell lung cancer (#SCLC) that searches for disease-linked autoantibodies could address the need for a feasible test for earlier diagnosis in patients with this aggressive #cancer, show researchers at @fredhutch. scim.ag/1aq
One in every three Nebraskans will hear the words “you have cancer” in their lifetime. Dr. Ken Cowan is director and physician-in-chief at @unmc's Fred & Pamela Buffett Cancer Center—which is improving cancer research and treatment for all. Read his story: nebraska.edu/nuforne/ken-cow…
Congratulations to Dr. Nasser Lab @NasserWasim on publishing “MicroRNA-1 attenuates the growth and metastasis of small cell lung cancer through CXCR4/FOXM1/RRM2 axis” in Molecular Cancer molecular-cancer.biomedcentr…. Parvez Khan is first author
Review article from Dr. Wasim Nasser Lab @NasserWasim “Epigenetic alterations fuel brain metastasis via regulating inflammatory cascade”
published in Seminars in Cell and Developmental Biology
sciencedirect.com/science/ar…
Review article from Dr. Wasim Nasser Lab
@NasserWasim “Emerging role of chemokines in small cell lung cancer: Road signs for metastasis, heterogeneity, and immune response” published in the Seminars in Cancer Biology
sciencedirect.com/science/ar…
How does tumor heterogeneity impact #metastasis?
I am excited to share our latest pre-print: We used patient derived-xenograft models (PDX) of #breastcancer to examine the contributions of tumor heterogeneity on metastasis at single-cell resolution.
doi.org/10.1101/2022.08.04.5…
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