BMB Associate Professor at the University of Nebraska Medical Center. Interested in lipid droplets, vesicle trafficking, cell signaling, and liver disease.
Excited to share our new paper: 'LASER couples damage sensing to ESCRT assembly for lysosome repair.' Congrats to dream team @clairegoul and @aakritijain24 for uncovering a new lysosome repair pathway and its connection to neurodegeneration. bit.ly/49FCPoq
Great news! Early registration for the FASEB #LipidSRC has been extended until June 14! It is not too late to submit an abstract and present at the premier North American #LipidDroplet meeting events.faseb.org/event/544fc…
New preprint from our team @chiluncellbio : OPA1 doesn’t just regulate mitochondrial fusion — a subpopulation localizes to lipid droplets and actively controls fatty acid release.
biorxiv.org/content/10.64898….
Summer is approaching & so is the 2026 Lipid Droplets: From Mechanisms to Disease FASEB SRC (July 26-30 in Scottsdale, AZ)!
Interested in lipids? Join this amazing summer research conference!
Abstracts due May 31,
Early registration June 14.
events.faseb.org/event/Lipid…
Updated preprint! Here, we identify an SREBP-dependent fatty acid sensing metabolic switch in Drosophila, enabling dramatic metabolic rewiring within adipose tissue that boosts carbohydrate metabolism in the absence of fat.
Read more here:
biorxiv.org/content/10.1101/…
1/3 Thrilled to see our paper led by Kirandeep Deol is out! We used CRISPR screens to uncover regulators of the ferroptosis suppressor FSP1. key discovery: vitamin B2 metabolism stabilizes FSP1 via FAD, revealing a new way vitamins regulate ferroptosis.
nature.com/articles/s41594-0…
Excited to share our new paper in @FEBSJournal! With @OndrejKuda & @FedorovaLab we show how LDs reshape the lipidome of PUFA-exposed cells & shift function within the same cell, revealing a context-dependent role in ferroptosis. Congrats Ana & @Lejaperne! shorturl.at/TyRl1
Happy Holidays!
Warm wishes from the
Department of Biochemistry and Molecular Biology! May your holidays be filled with joy, rest, and inspiration, and the New Year bring new discoveries and success!!
Happy to see some of our work on #lipiddroplets and #ferroptosis finally out! We reveal opposing roles for LDs in ferroptosis - protection vs. sensitization - balancing membrane and mitochondrial homeostasis with LD-localized lipid oxidation. biorxiv.org/content/10.1101/…
We isolated and omics analyzed lipid droplets from human carotid artery plaques. Enrichment (16.5%) of arachidonic acid in cholesteryl ester indicates that the plaque is an inflammatory core. biorxiv.org/content/10.1101/…
We built upon a key discovery made by @KivancBirsoy and unveiled additional mechanisms for regulating lipid synthesis. CHP1 promotes lipid droplet growth and regulates the localization of key enzymes for triacylglycerol synthesis | PNAS pnas.org/doi/10.1073/pnas.25…
Review article from Dr. Shott lab @micahschott "Lipid Droplet Dynamics in Alcoholic Steatohepatitis" ajp.amjpathol.org/article/S0…
Delia Omar is the first author of the paper
Happy to see some of our work on #lipiddroplets and #ferroptosis finally out! We reveal opposing roles for LDs in ferroptosis - protection vs. sensitization - balancing membrane and mitochondrial homeostasis with LD-localized lipid oxidation. biorxiv.org/content/10.1101/…