Inflammaging and Sarcopenia as Interconnected Hallmarks of Aging: Integrative Roles of Bioactive Compounds and Lifestyle Interventions ▶️ Age-related functional decline is increasingly linked to chronic low-grade inflammation (inflammaging) & sarcopenia, two interconnected processes contributing to frailty, metabolic dysregulation, & impaired physical function. ✅️ Natural bioactive compounds & lifestyle-based interventions represent promising approaches for targeting biological processes implicated in inflammaging & sarcopenia. ✅️ This review highlights the importance of adaptive redox regulation, metabolic resilience, & evidence-based lifestyle strategies in healthy aging. mdpi.com/2072-6643/18/12/192… @HealthyFellow @DHPSP Conceptual schematic framework illustrating hypothesized and partially evidence-supported interactions among lifestyle interventions, bioactive compounds, molecular signaling pathways, & functional outcomes in healthy aging. The figure is intended for conceptual interpretation & does not imply direct causal relationships for all depicted interactions.

YprA-family helicases provide the missing link between diverse prokaryotic immune systems sciencedirect.com/science/ar… #OpenAccess #Microbiology #Immunity

Moving beyond single-disease approaches, integrating multiomics biomarkers and life-course perspectives could enable earlier, more precise prevention and treatment strategies for cardiometabolic multiple long-term conditions. New research in @TheLancet reveals that conditions like type 2 diabetes, heart disease, chronic kidney disease, and fatty liver disease don't develop in isolation - they're driven by shared biological mechanisms including insulin resistance, chronic #inflammation, and ectopic fat deposition. The study highlights how social determinants of #health, early-life nutrition, air pollution, and even endocrine-disrupting chemicals #interact with genetic susceptibility to accelerate disease clustering. thelancet.com/action/showPdf…

Nearly 1.2 billion people - that’s roughly 1 in 7 - struggled with a #mental disorder in 2023. And a new study reveals a staggering 95.5% rise since 1990. The biggest jumps? #Anxiety and #depression, which were also the most common disorders worldwide. thelancet.com/journals/lance…

"The Influence of Prosthetic Obturators on Quality of Life in Individuals with Maxillectomy Defects" - by Minseok Kim @UOPacific @dugoni_dental scholarlycommons.pacific.edu… #OpenAccess #OralHealth

"Pathways to Success: The Role of Self-Efficacy and Social Capital in Diversifying the #Healthcare Workforce" - by Chelsey Louw @UOPacific @UOPacificSHS scholarlycommons.pacific.edu… #OpenAccess #education

"Investigating the Clinical Relevance of a Modified 10 Meter Walk Test for Physical Therapists in the Treatment of Acute Stroke Populations: Insights from a Case Series" by Sarah Rowe, Gwen Juha, Joy Williams @sunsopeningband @aboutKP @UOPacific scholarlycommons.pacific.edu…

After having consulted the #DRC and #Uganda where the #Ebola disease caused by Bundibugyo virus is known to be currently occurring, I determine that the epidemic constitutes a public health emergency of international concern (PHEIC), as defined in the provisions of IHR. My full statement: bit.ly/4wGGiwX

The history of race-based correction of lung-capacity measures can be traced to a pre–Civil War belief among slave owners that slaves had naturally inferior lung capacity. Despite work to show that race-corrected spirometers mask lung-disease severity in Black patients, the majority of U.S. hospitals still use them. Listen to the latest episode of Intention to Treat: nej.md/3RsGBLv

Neanderthals went to the dentist (really). New evidence shows #Neanderthals practiced dental surgery 59,000 years ago, revealing skill, care & causal reasoning far more advanced than long assumed. economist.com/science-and-te… #OralHealth #dentistry

Depression may be contagious - here’s the science behind it. We often think of #depression as a purely internal struggle. But a compelling body of research suggests otherwise: depression can spread through social networks, much like an infectious disease. sciencedirect.com/science/ar…

"Examining the Benefits of a Standardized Protocol for Hyperglycemia Screening in Adult Oncology Patients: A Pilot Study" - by Alexa Dashko at St. Joseph's University Med Center scholarlycommons.pacific.edu… #OpenAccess #cancer #diabetes

"Evaluating Clinical-Academic Partnerships in #PhysicalTherapy #Education: A Critically Appraised Topic on Available Assessment Tools" by Jocelin Friedman, Hannah Bennett et al. @ChapmanU @EmoryUniversity scholarlycommons.pacific.edu… #OpenAccess

Hot off the press! "Building capacity, changing teaching practices: insights from a professional development program for educators in a low-income country" - by Caroline Havery, Mary Kililo et al. at Univ Technology Sydney scholarlycommons.pacific.edu… #OpenAccess #health

Hot off the press! "Late Local Recurrence of #GastricCancer After Preoperative Radiochemother Radiochemotherapy: Three Case Reports and Literature Review" - by Mateusz Gajek, Magdalena Szymala-Cortez et al. from Gilwice, Poland scholarlycommons.pacific.edu… #OpenAccess #cancer

Cross-cohort meta-analysis reveals conserved gut microbiome signatures of #insomnia. Insomnia shows a reproducible gut #microbiome signature, with specific taxa driving targeted functional shifts. sciencedirect.com/science/ar… #OpenAccess

Hot off the press! "Racial #Disparities Among Pregnant Women of Color and Their High Risk for Developing Periodontal Disease" - by Darrylnn Mayo @UOPacific scholarlycommons.pacific.edu… #OpenAccess #OralHealth #pregnancy

Hot off the press! "Behavioral Personal Protective Equipment and Staff Safety: A Pilot Study Evaluating Its Impact Among Speech-Language Pathologists" - by Jennifer J. Bekins @UOPacific scholarlycommons.pacific.edu… #OpenAccess

Whether you're #walking, swimming 🏊🏽‍♂️ , or lifting weights 🏋️‍♀️ , the protective #PhysicalActivity payoff comes from making movement a lifelong habit, not a occasional burst. Small steps, sustained over decades, add up to major #health gains. New research in @NatureComms followed 231,000 people for 32 years and found that consistency matters as much as volume when it comes to #physicalactivity and chronic disease prevention. People who steadily met the recommended 7.5 MET-hours/week had lower risk of #NCD noncommunicable diseases such as #diabetes, heart disease, and #cancer - even compared to those who exercised intensely but sporadically. Staying #active through middle adulthood (ages 40–60) was linked to 10–28% lower disease risk after 60. nature.com/articles/s41467-0…

That line looks awfully vertical.