Discovery Science in the Genome Integrity field. Opinions are our own.

Joined September 2021
25 Photos and videos
Pinned Tweet
Our new work lead by Lorenzo Galanti is out in @NatureComms. New function of DDK in regulating HR and DSB resection in budding yeast and human cells. Check it out here nature.com/articles/s41467-0…
2
5
36
9,820
PfanderLab retweeted
Publication alert! 📰 Great job to @hopfnerlab and collaborators on the new publication in @NatureComms! Read more about it here: nature.com/articles/s41467-0…
Check out our latest structural paper about human OGG1 processing DNA lesions within nucleosome core particles, in collaboration with Chuanzheng Zhou's lab. #DNArepair #cryoEM nature.com/articles/s41467-0…
1
4
628
PfanderLab retweeted
We are pleased to inform you that the meeting “From Genome Instability to Cancer: A tribute to Angelos Constantinou” that will take place in Carry-Le-Rouet from March 10th to March 13th 2025 is now open for registration on the link: tribute2angelos.fr/page/home…
2
30
48
5,281
PfanderLab retweeted
Replying to @RogerRogergr
@RogerRogergr we are really looking forward to your presentation at #DDRCT25 in Lisbon🌞 Registration is OPEN and we have short talk spaces available. 📣Help us spread the word - Please RT to let your followers know! Thank you! Find out more: bit.ly/3BTmZbQ
2
5
347
PfanderLab retweeted
📢The deadline is approaching!! This is your last week to apply for exciting projects @IMPRS_LM in the labs of Ralf Erdmann, @kw_kliza, @hemmo_lab, @AndreaMusacchi1, @PfanderLab, Barbara Saccà, Daniel Summerer, Jörg Tatzelt, @BTrappmann, @LabWestermann & @winklhofer_lab
5
10
2,905
PfanderLab retweeted
Congratulations to the best poster prize winners Vanessa Borges-Pires, Anita Jopkiewicz, Jessica Spindler, Maximilian Götz, Na Wei, George Galea of the German Society for DNA repair DGDR meeting 2024 in Cologne @MPIAGE @CGA_age @CECAD_ @UniCologne @spanier55 @PfanderLab
4
2
22
2,146
PfanderLab retweeted
An intact genetic information is the fundament of life. If you are interested to apply precision genome engineering and state-of-the-art sequencing technology join the @PfanderLab @IMPRS_LM #PhDposition #IMPRS #cellbiology #DNAreplication #genomeengineering
4
7
641
PfanderLab retweeted
Pleasure to host the 2024 meeting of the German Society for DNA Repair ⁦@MPIAGE⁩ ⁦@CECAD_⁩ in Cologne with outstanding international guest speakers and the amazing community of DNA repair researchers in Germany with ⁦@spanier55⁩ ⁦⁦@PfanderLab
4
6
55
5,147
PfanderLab retweeted
Mechanism of homology search expansion during recombinational DNA break repair in Saccharomyces cerevisiae dlvr.it/TCxvLF
1
13
75
7,813
PfanderLab retweeted
📢Are you eager to join an international community of scientists to tackle novel and exciting research projects in the areas of #biochemistry, #structuralbiology, #cellbiology, #chemicalbiology and #syntheticbiology? Applications for the @IMPRS_LM #PhDprogram are now OPEN!!!
9
16
4,670
PfanderLab retweeted
CMG helicase disassembly is essential and driven by two pathways in budding yeast Karim Labib and colleagues show that Pif1-family helicases mediate an ancestral pathway for ‘old’ #replisome disassembly during the subsequent S-phase embopress.org/doi/full/10.10…
12
30
3,037
PfanderLab retweeted
10 Jul 2024
Check out our latest paper showing that HLTF removes Cas9 from DNA, explaining phenotypic differences when using the two Cas9 nickase variants. Important for gene editing! Thanks to @giordano_reg & Rosaria and @MartinJinek @taekjip @nussenza nature.com/articles/s41467-0…
3
31
107
9,212
24 Jun 2024
Jim - being a superstar of yeast genetics has to be fantastic. People must ask you for selfies all the time... 😃
23 Jun 2024
Who needs a duckboat?
1
819
PfanderLab retweeted
Grateful for the opportunity to present our work this week, and happy to see three other former graduate students of the late Stefan Jentsch on this list @PfanderLab @RapeLab @stingele_lab. This one is for you, Stefan!
18 May 2024
Where is the spring? Are you ready for the summer? Social DNAing is. Check out our 2024 late spring and summer speakers. The website will be updated soon: cancer.columbia.edu/research…. Thank you for helping us RT.
1
10
1,907
PfanderLab retweeted
8
11
1,811
PfanderLab retweeted
How does Mcm10 activate an origin of replication? Find the answer in our paper published today in @NatureSMB. Congratulations to Sarah Henrikus & our fantastic lab! 🥳🎉 rdcu.be/dIdI4 Great collaboration with Marta, Allie and John from @DiffleyLab @TheCrick
12
32
112
11,834
PfanderLab retweeted
AlphaFold3 is insane. MutS protein (green) recognizes base mismatches in DNA (gray), after which it slides off to find MutL matchmaker protein (blue), which positions and activates MutH nuclease (pink) to nick a hemimethylated GATC sequence (red) to activate removal and repair of the mismatched strand.
30
274
1,827
469,720
PfanderLab retweeted
Registration for the #MunichYeastMeeting 2024 with keynote speakers @liti_nice and Helle Ulrich is now open. Join us on November 15 @HelmholtzMunich schmollerlab.com/munich-yeas…
6
10
1,353
PfanderLab retweeted
Research in the DNA replication field is progressing rapidly! Building on the success of the inaugural 2022 Meeting, The Biochemical Society is delighted to invite you to join us for the second UK DNA Replication Meeting. Register now: ow.ly/Zx8y50Rn5uq
18
21
3,737