Focused on defining the mechanisms that underlie the transcriptional and epigenetic regulation of cardiac electrophysiology in human and murine models.

Joined September 2021
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The Rentschler Lab is looking to expand our team! Are you interested #cardiology #electrophysiology #tissueengineering #radiotherapy? We have opportunities for research technicians, post-docs, and staff scientists! Check out the job posting below! wustl.wd1.myworkdayjobs.com/…

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Stacey Rentschler Lab @ WUSTL retweeted
It's the 10-year anniv of the 1st patient treated with StereoTactic Arrhythmia Radiotherapy (STAR) by @DoctorPhillEP & @SBRT_CR! We've given many talks, been featured in media, formed a center, held intl symposiums, helped 100 centers begin STAR & now treated our 100th patient!
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Stacey Rentschler Lab @ WUSTL retweeted
.@brianzenger provides further mechanistic insights into effects of #radiotherapy on #VT. - cc @RentschlerLab @DoctorPhillEP #HRS2025 #EPeeps #Cardiotwitter #2025Pacesetter
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Stacey Rentschler Lab @ WUSTL retweeted
1 Apr 2025
A role for protein aggregates in heart failure? This issue’s cover features work from ASCI member Abhinav Diwan @DiwanlabWustl & team @washumedicine on protein aggregation in the post–myocardial infarction myocardium: buff.ly/YOFkNCq
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Stacey Rentschler Lab @ WUSTL retweeted
Early-onset colorectal cancer is expected to become the leading cause of #cancer death in ages 20 to 49 in the U.S. by 2030. Research is urgently needed to better detect and treat patients, argues this #SciencePerspective: scim.ag/4i3RSdS #ColorectalCancerAwarenessMonth
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Stacey Rentschler Lab @ WUSTL retweeted
8 Feb 2025
Imagine running a restaurant & suddenly only having budget for ingredients & chefs—no rent, electricity, heat, water, support staff, insurance, trash, toilet paper. This is what 'cutting indirects' did to every major biomedical center & hospital in the US.
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Stacey Rentschler Lab @ WUSTL retweeted
Big #RegenerativeMedicine advance! New study demonstrates the use of iPSC-heart muscle to treat a patient with heart failure. The patches successfully engrafted, contributing to heart repair. Patient survived 3 months before receiving a heart transplant nature.com/articles/s41586-0…

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Stacey Rentschler Lab @ WUSTL retweeted
15 Jan 2025
If you treat lung cancer & have queries about radiation heart disease then check out this new @WashUMedRadOnc paper! 100 years on from its 1st description we summarise what is known (and not known) & highlight priorities for the field to maximise patient benefit
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Stacey Rentschler Lab @ WUSTL retweeted
#SNOSTORM2024 is underway with Day 1! So much to learn about Cardiac Radioablation! #CRAforVT #RadiateVT #Epeeps @stopstormEU @joostverhoeff @DoctorPhillEP @gdhugo @SBRT_CR @RentschlerLab @samsonpp
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Stacey Rentschler Lab @ WUSTL retweeted
Together with @American_Heart, we are proud to present our Collaborative Science in #SingleVentricle Heart Disease Program awardees! Proposals from 5 outstanding research teams were selected for funding, for a total investment of over $13M. Read more: additionalventures.org/news/…

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Stacey Rentschler Lab @ WUSTL retweeted
We think this one is groundbreaking: Do you wonder how #SGLT2 inhibitors protect from heart failure? We show that #empagliflozen directly activates PANK1, rate-limiting for CoA synthesis, in human hearts. You read it here first! biorxiv.org/content/10.1101/…
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Stacey Rentschler Lab @ WUSTL retweeted
Ecstatic to be awarded the K99 from @nih_nhlbi. Many thanks to my family, friends, and mentors, including my PhD mentor @RentschlerLab, for their continued support. Special shout-out to my lab mates and my postdoc mentor @jmartinlab. Looking forward to the science ahead!
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Stacey Rentschler Lab @ WUSTL retweeted
Join us for #SNOSTORM2024 Sep 2nd-4th in Amsterdam! Registration is now open. You can find more information, including link for registration, here: bit.ly/SNOSTORM2024. We hope to see you there! #CRAforVT #radiateVT #EPeeps #CNCR @SBRT_CR @DoctorPhillEP @gdhugo @joostverhoeff
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Heart rhythm in Boston is wrapping up! Great science and wonderful to see so many friends and colleagues 😊 @bjboukens @glennfishman
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Stacey Rentschler Lab @ WUSTL retweeted
Congratulations to @glennfishman on receiving the Heart Rhythm Society’s 2024 Distinguished Basic Scientist award! As director of the Leon H. Charney Division of Cardiology, Dr. Fishman is a luminary in cardiac electrophysiology. Learn more: med.nyu.edu/faculty/glenn-i-…
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A huge congratulations to my PhD advisor Glenn Fishman for receiving the Distinguished Basic Scientist Award at HRS. So well deserved Glenn, you have been such a great mentor and friend as well as an outstanding scientist! @glennfishman @EPeeps @DavidParkLab1
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Congratulations to Sam Jordan, a Sarnoff fellow in my lab, for delivering a fantastic talk at the Weinstein Cardiovascular Development conference in Montreal!
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Stacey Rentschler Lab @ WUSTL retweeted
hypertrophic cardiomyopathy (Myosin Binding Protein C mutation) and associated defects in myofilament structure and calcium handling. cell.com/iscience/fulltext/S…. Congrats to Mimi and the rest of the team!
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Stacey Rentschler Lab @ WUSTL retweeted
Excited to post our work, just accepted in iScience. Led by @mimi_guo6, our team used biomaterials to control the mechanical load that iPSC-derived heart muscles work against. Both mechanical load and 3D tissue environment proved essential to observe hypertrophy linked to
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