Stanford University medical oncologist and cancer scientist, and Director of the Stanford Cancer Institute. Follows and retweets are not endorsements.

Joined November 2018
995 Photos and videos
We’re basically out of capacity. Growing demand for complex cancer care is why expanded access in Redwood City matters now. brnw.ch/21x3iTR
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This center brings that breadth of world-class science together under one roof for the benefit of patients locally and globally.
A proposed cancer center in Redwood City would combine patient care and research. The city will receive a formal updated project description, and Stanford Medicine will host two community webinars. brnw.ch/21x3f0A
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SCI member Michael Lin & others developed MIDAS, a rapid protein-engineering platform that could accelerate cancer drug & diagnostic development by helping researchers quickly build & test thousands of protein variants in mammalian cells. #Bioengineering brnw.ch/21x3blA
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SCI member @summerhanlab & others found that in #EGFR mutant advanced #NSCLC treated with EGFR-TKIs, patients with lower tumor burden had better overall survival, suggesting tumor burden may help predict outcomes and guide treatment decisions. brnw.ch/21x37PG
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SCI member @SnyderShot & others mapped multiomics across ancestry, geography & age, revealing ethnicity-linked immune, metabolic & microbiome differences plus how relocation reshapes biological aging and cholesterol pathways. brnw.ch/21x347H
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SCI member Mindie Nguyen & colleagues found cfDNA HelioLiver Dx blood test outperforms ultrasound for early #HepatocellularCarcinoma detection, showing superior sensitivity and non-inferior specificity vs MRI gold standard. brnw.ch/21x30mb
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An international framework, developed by a global team including SCI member @cncurtis, guides clinical translation of molecular classifiers in #osteosarcoma, highlighting pre-treatment ctDNA for implementation, with other biomarkers needing validation. brnw.ch/21x2WqI
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SCI member @xrtcell & others show that combining targeted #RadiationTherapy with an experimental immune-boosting drug (BO-112) & anti-PD-1 therapy before surgery may help the immune system fight aggressive #SoftTissueSarcomas. brnw.ch/21x2SeG
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Ronald Castellino, pioneer in oncologic radiology, dies at 88. Castellino founded the first #RadiationOncology division at Stanford , led the diagnostic radiology department, and made important contributions to research in imaging the lymphatic system.brnw.ch/21x2JP5
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SCI member Beth Beadle & others report that in p16 #OropharyngealCancer, quality of life outcomes at 6 months were similar for accelerated radiation with cisplatin or cetuximab, with persistent issues in dry mouth, sticky saliva, and senses. brnw.ch/21x2JOy
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SCI member Chris Garcia & others use catch-bond engineering to enhance weak TCRs, boosting TCR potency against prostate cancer antigens while maintaining specificity. This strategy could overcome immune tolerance and improve TCR-based #CancerImmunotherapy. brnw.ch/21x2D6I
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SCI member Nathanael Gray & others report that TRAP-1, a mutant-specific small molecule, activates p53Y220C via a ternary complex, restoring tumor suppressor function and inducing senescence and apoptosis in cancer cells. brnw.ch/21x2B1m #DrugDiscovery
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SCI member Lei Qi & others show that engineered trogocytosis enables programmable #MacromoleculeDelivery, allowing tunable, cell-specific transfer of therapeutic proteins and genome-editing tools across diverse cell types. brnw.ch/21x2wNv #ProteinDelivery
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A multidisciplinary expert thoracic panel, including SCI members Joel Neal and Joseph Shrager, released 19 consensus recommendations on managing locally advanced #LungCancer, covering resectability, neoadjuvant, and adjuvant therapies. brnw.ch/21x2sDC
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SCI Esther John & others found that adding polygenic risk scores (PRS) to mammographic density (MD) didn’t improve contralateral #BreastCancer (CBC) risk prediction. MD remains the main predictor for CBC risk. brnw.ch/21x2obk
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SCI member @AaronNewmanLab & others report a machine-learning framework identifying nine #SpatialTME ecotypes in the TumorMicroenvironment, linked to immunotherapy response and detectable in plasma cfDNA. brnw.ch/21x2iAF
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SCI member Marvin Langston & others found that renal cell carcinoma incidence >, particularly among Hispanic, Black, and low-nSES groups. While overall mortality <, these groups faced > death rates, highlighting #RCC health equity concerns. brnw.ch/21x2frh
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A @STS_CTsurgery panel, including SCI member Joe Shrager, developed 19 consensus recommendations on managing locally advanced #NSCLC, focusing on resectability, the role of neoadjuvant & adjuvant therapies, & multidisciplinary treatment approaches. brnw.ch/21x2bhI
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SCI member @SurbhiSidanaMD & others found that high #BCMA expression at baseline predicts better outcomes with BCMA CAR-T therapy in #MultipleMyeloma. However, BCMA expression often decreases at relapse, which may impact future treatment strategies. brnw.ch/21x272Z
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SCI member @l_schapira & others found that in young female cancer survivors, fear of cancer recurrence (FCR) predicts future chronic pain, but pain does not predict FCR. brnw.ch/21x22Yt
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