She persisted and her dreams came true 😭 Somebody pinch this girl from the 100x35 island as she matches in her dream subspecialty 🥹🥹🥹🥹🥹 so so excited and humbled!!

Presented at #EULAR2026: In a phase 3 trial, obexelimab led to a lower risk of disease flares than placebo among patients with IgG4-related disease. Glucocorticoid use was lower and the incidence of remission was higher with obexelimab than with placebo. Full INDIGO trial results: nej.md/4fKYQG4 Editorial: Obexelimab and the Promise of Nondepleting B-Cell Therapy in IgG4-Related Disease nej.md/4fLybcd @eular_org

Cheers, chills, and a standing ovation when RASolute 302 showed unprecedented survival on daraxonrasib for patients with progressive pancreatic cancer Seldom do you sense you’re witnessing a historic moment in cancer care but this feels like ras targeting has arrived #ASCO26

Is it possible to get diarrhoea symptoms after gallbladder surgery? The answer is yes - it’s called bile acid diarrhoea (BAD) and it’s more common than we think.

How to manage acute pancreatitis in 2026? Great talk by @DeMadaria the lead author of the landmark Waterfall trial @DDWMeeting! COX-2 inhibitors might be helpful. @AmerGastroAssn @ASGEendoscopy @ibdgijami @JElmunzer #DDW2026 #PGcourse

Ustekinumab for ileal stricturing Crohn’s disease—an international multicenter retrospective cohort study academic.oup.com/ecco-jcc/ar…. Congratulations to @SaraElOualiMD and the #STARConsortium. Stay tuned for more coming soon… @tinahamd @ownyourcrohns @MRegueiroMD @DrsMeena

🚨 IMPORTANT ANNOUNCEMENT 🚨 🔥 BLOCKBUSTER multilingual collab from our GI fellows for Colorectal Cancer Awareness Month 🫱🏻‍🫲🏾🎬 🇺🇸🇱🇧🇫🇷🇪🇸🇮🇳🇵🇰🇨🇳🇳🇬 ‼️ Colorectal Cancer Screening Saves Lives ‼️ Send this to family and friends 📲 Stay on top of your health! 🫵

#CGH4ALL @AGA_CGH 📣 JAKi vs TNFi in IBD (2016–2023 cohort), Important real-world data to guide biologic selection in #IBD 🔹 Higher overall infection risk with JAK inhibitors 🔹 No increased risk of serious infections, VTE, or MACE 🔹 Overall safety profile comparable for major AEs #IBD #GITwitter #MedTwitter #AdverseEffects 🔗cghjournal.org/article/S1542… Reported by @AasthaBharwad @vipuljairath, @ChrisMa_YYC, @virgisolitano, @eathar_s, @DhruvAh08, @TakuKobayashiM1 , @PolychronisP, @ErnstKuipers, @DaniyalAbbasMD, @LaurenLoebMD, @MarkPochapin, @SunandaKaneMD

🔥 Most endoscopists start their biopsies in the wrong place. (And the AGA guidelines might be leading you astray...) The full 19-minute lecture reveals: → The Prague Classification secret that changes how you measure Barrett's → Why palisade veins matter MORE than gastric folds for finding the true GE junction → The "pseudo-fold" trap that makes esophagus look like stomach → Where dysplasia REALLY hides (hint: it's not evenly distributed) → The Seattle Protocol modification that doubled detection sensitivity You don't want to be the endoscopist sending the pathologist gastric mucosa when you're hunting for Barrett's dysplasia. Full lecture here: newsletter.endocollab.com/p/… (19 minutes that could change how you approach every Barrett's case)

9/9 Thank you & please check out @ACG_EBGI summaries @ gi.org/ebgi Stay tuned for next week w @Montalvan214 !🌟

8/9 Caution ⚠️ Population was mostly older M veterans, limiting applicability to other populations ⚠️Measurement of mucosa is subjective ⚠️Absolute # of dysplasia events in the USBE subgroup was modest, causing wide CIs ⚠️Retrospective data collection can introduce bias

7/9 My Practice🩺🩺 💠For @RomyChamoun & @SamSchuelerMD their biopsy approach remains consistent with guidelines from the ACG and most other national/international guidelines

6/9 Results🧪 💠Persistence was notable: >½ of USBE cases had BE/intestinal metaplasia on follow up➡️ many of these represent true metaplasia vs sampling artifact or inflammation. 💠Race & ethnicity influence outcomes➡️White &Hispanics having⬆️ risk of persistence vs Black pts

5/9 Results🧪 💠USBE was nearly 1/4 of new Barrett’s cases 💠Persistent USBE was associated with 11.6% cumulative dysplasia risk 💠Dysplasia incidence rate didn't differ significantly from ≥1 cm BE. 📍USBE may carry more prognostic weight than previously thought‼️

4/9 Design 💠A Retrospective cohort seeing long-term endoscopic & histologic outcomes over 32 years @ a VAH in TX 💠Patients diagnosed with BE from 1990-2022 with 🔬-confirmed intestinal metaplasia and at least 1 follow-up endoscopy, compared to BE ≥1 cm by Prague criteria.

3/9 Definitions & Primary Endpoints 💠Ultrashort Barrett’s esophagus (USBE): <1 cm of columnar-lined mucosa w/ intestinal metaplasia 💠1∘ endpoint: persistence of BE/intestinal metaplasia on follow-up endoscopy. 💠2∘ endpoint: development of definite dysplasia/neoplasia

2/9 Importance🌟 This study 🔍 provides long-term outcome data 🖥️ to help 👩‍⚕️understand if USBE is clinically meaningful It challenges the assumption that short segments are benign and transient.

Eosinophilic esophagitis: step up 🆚 step down with @JoyWChang #ACG2025

Exceptional presentation by Dr. Afzali on treatment strategies for Ulcerative Colitis at #ACG2025. Great takeaways on optimizing outcomes and personalizing IBD care! 🌿💊 #GI #IBD #UlcerativeColitis 📚📚 @IBD_Afzali #ACG2025 #IBD #GI

GI Toolkit for Gastroparesis (more than prokinetics) ▪️Ondansetron 8 mg TID ▪️Granisetron patch 34 mg weekly ▪️Prochlorperazine 5-10 mg QID ▪️Chlorpromazine 10-25 mg QID ▪️Scopolamine patch q3d ▪️Aprepitant 80 mg QD ▪️Meclizine 12.5-25 mg TID ▪️Dronabinol 5-10 mg TID #ACG2025

The Difficult Colonoscopy is humbling to all endoscopists. My Pearls : #1 Female Patients If hysterectomy or diverticulitis, use pedi colonoscope water immersion. (Angulated colon) If chronic idiopathic constipation or visceral obese, use adult colonoscope (redundant colon)