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Dr. Sebastian Fica, PhD @Seb_Fica

Biochemist at heart, dabbling in electron microscopy to uncover molecular mechanisms of nifty RNA-protein complexes 🔬🇷🇴🇺🇸🇬🇧🏳️‍🌈

Joined February 2017
  • Tweets 2,347
  • Following 289
  • Followers 896
86 Photos and videos
We found a welcoming journal home for our work explaining how the spliceosome toggles between competing conformations during splicing catalysis sciencedirect.com/science/ar…
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Cambridge Lockdown v3 - the winter, unfortunately more scary, edition 😬
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Beautiful work from @SteitzLab - I remember hearing about this intriguing mechanism of RNA stabilisation after my seminar at Yale last year; very nice to see this published
Joan Steitz Lab@SteitzLab
10 Jan 2021
We are excited to share our @ScienceMagazine study on RNA triple helices led by Seyed Torabi! Here we describe the structure of an RNA element that protects the poly(A) tail through the formation of a 3ʹ-end binding pocket and other RNA interactions. science.sciencemag.org/conte…
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Dr. Sebastian Fica, PhD retweeted
Joan Steitz Lab@SteitzLab
10 Jan 2021
We are excited to share our @ScienceMagazine study on RNA triple helices led by Seyed Torabi! Here we describe the structure of an RNA element that protects the poly(A) tail through the formation of a 3ʹ-end binding pocket and other RNA interactions. science.sciencemag.org/conte…

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Dr. Sebastian Fica, PhD retweeted
Matt Higgins@ParasiteMatt
6 Jan 2021
Two days left to apply for this program! Come to Oxford to train as a structural biologist....exciting projects, great facilities, outstanding colleagues and supervisors, generous support from @wellcometrust. Why would you not apply?!
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Dr. Sebastian Fica, PhD retweeted
Angela Rayner
@AngelaRayner
4 Jan 2021
I tell you what, you don't hear @BorisJohnson and @MattHancock talking about the £22bn Serco Test and Trace system as the way to control the virus anymore do you?
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Scott Duncan@ScottDuncanWX
3 Jan 2021
Enormous snow flakes coming down in Northumberland, England today! Who else could watch this all day? 🎥 @deborahparkin x.com/deborahparkin/status/1…

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Prof Sir Mene Pangalos FRS@MenePangalos
3 Jan 2021
Some of the reporting by the media really has been atrocious. Instead of trying to help they seem more intent on stirring up an inaccurate story. BMJ urges NYT to correct vaccine 'mixing' article bbc.co.uk/news/uk-55519042

Coronavirus: BMJ urges NYT to correct vaccine 'mixing' article

The medical journal's editor says UK guidelines don't recommend giving different coronavirus jabs.

bbc.co.uk
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A rather gloomy start of 2021 in Cambridge 😢 Mask up 😷. Stay safe, help end this pandemic !
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Dr. Sebastian Fica, PhD retweeted
Epigenetic Hulk@epigenetichulk
2 Jan 2021
JUST BE CLEAR! EPIGENETIC HULK NOT LADY WISTLEDOWN!
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Sadly 1666 was the year when the great fire of London started exactly in the bakery in Pudding Lane ... just a reminder for those placing too much hope on 2021 😬
Jonathan Healey@SocialHistoryOx
31 Dec 2020
‘The Year of Our Lorde 1665 hath been such a terrible one for ye plague. I cannot wait for 1666, for which I have especial excitement to trye the newe bakery that hath opened on Pudding Lane.’ Samuel Pepys, Diary Entry, 31 December 1665.
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Dr. Sebastian Fica, PhD retweeted
Jonathan Healey@SocialHistoryOx
31 Dec 2020
‘The Year of Our Lorde 1665 hath been such a terrible one for ye plague. I cannot wait for 1666, for which I have especial excitement to trye the newe bakery that hath opened on Pudding Lane.’ Samuel Pepys, Diary Entry, 31 December 1665.
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Dr. Sebastian Fica, PhD retweeted
A Cambridge Diary@acambridgediary
1 Jan 2021
For the first time in its history, Cambridge Market. has been shut down and barricaded - coincidentally on the day of Brexit 'freedom and sovereignty'. I can't think of more ironic metaphor.
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Dr. Sebastian Fica, PhD retweeted
Chromatin Haiku@ChromatinHaiku
1 Jan 2021
In the beginning... Miescher's "Nuclein" extract First chromatin prep #ChromatinHaiku #1871
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Beautiful work and also an illustration of why the truly physiologically relevant protein folding problem needs to be studied in the cellular context.
Bukau Lab@BukauLab
1 Jan 2021
Our first 2021 paper reveals the prevalence and mechanism of a co-translational protein assembly mechanism in human cells: co-co assembly. Congratulations to the co-co team @KaiFenzl, @matildebertolin and @guenter_kramer! science.sciencemag.org/conte… @Sciart by @munafomarzia 1/6
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Dr. Sebastian Fica, PhD retweeted
Bukau Lab@BukauLab
1 Jan 2021
Our first 2021 paper reveals the prevalence and mechanism of a co-translational protein assembly mechanism in human cells: co-co assembly. Congratulations to the co-co team @KaiFenzl, @matildebertolin and @guenter_kramer! science.sciencemag.org/conte… @Sciart by @munafomarzia 1/6
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An mRNA HIV vaccine looks promising in primates ... seems the dawn of a new era 😲
bioRxiv@biorxivpreprint
31 Dec 2020
Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates biorxiv.org/cgi/content/shor… #bioRxiv
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The power of in vitro reconstitution to understand biochemistry 😍
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Dr. Sebastian Fica, PhD retweeted
James B Watt MBE
@JamesBWatt
1 Jan 2021
We are in talks with the Government about using our closed @BrewDog bars as vaccination centres. We are also going to give everyone who gets vaccinated at a BrewDog bar a special commemorative beer. But what should we call it?
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Dr. Sebastian Fica, PhD retweeted
Larry the Cat
@Number10cat
1 Jan 2021
Dear EU So long and thanks for all the fish... X
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