Joined February 2015
1,054 Photos and videos
Shaalan Beg MD MBA FASCO retweeted
MAID program (Medical Assistance in Dying) is the topic of next week's #HealthcareUnfiltered. It's an important topic to address. what is it? who qualifies? is it good? bad? why and why not? As more states are legislating MAID, tune in Tue to learn more. Pls subscribe & share.
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Shaalan Beg MD MBA FASCO retweeted
🚨While @SpaceX goes IPO and the world's glued to @FIFAWorldCup ⚽🚀an interesting paper popped up for your Friday read @NatureMedicine 👉Frontier general LLMs (GPT-5.2, Gemini 3.1 Pro, Claude Opus 4.6) outperformed specialized clinical AI tools (OpenEvidence, UpToDate Expert AI) on medical knowledge, clinician alignment 1,800 blinded physician annotations on real clinical queries🤯 👉This result was unexpected 🤯🤔 👉"Specialized" ≠ "Better" @OncoAlert nature.com/articles/s41591-0…
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Shaalan Beg MD MBA FASCO retweeted
DART (NCI/SWOG S1609): comprehensive final results from dual checkpoint inhibition with CTLA-4 and PD-1 blockade in rare cancers - Final results (full access link below) thanks to all esp the patients involved in the 1st NCI rare tumor IO basket study! sciencedirect.com/science/ar…

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Shaalan Beg MD MBA FASCO retweeted
RASOLUTE-302 (GI Conference Highlights) from #ASCO26 w/ #BrianWolpin from @DanaFarber ✅ Other GI studies covered in our next episode w/ @NVijayvergiaMD Full 🗣️ ⭐️ “Oncology Brothers” podcast ⭐️ oncbrothers.com/rasolute-302… #OncTwitter #MedTwitter #gism @OncUpdates
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Shaalan Beg MD MBA FASCO retweeted
Jun 10
👏Big news! The #SeniorsAct now has 290 cosponsors, a key milestone. Momentum is building for bipartisan reforms to #FixPriorAuth & improve pt care. Congress needs to act NOW. Tell Congress to pass the Seniors Act. bit.ly/4e1Yf1x #ASCOAdvocacy
🚨NEWS: This week, my legislation, the "Improving Seniors' Timely Access to Care Act," reached 290 co-sponsors in the U.S. House -- an overwhelming bipartisan supermajority. This legislation puts patient care and patient outcomes first, and it will greatly modernize and streamline the prior authorization process. Learn more⬇️ kelly.house.gov/media/press-…
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Shaalan Beg MD MBA FASCO retweeted
Last year, we reported that KRAS PRMT5 is synergistic in MTAP-null PDAC (doi.org/10.1158/0008-5472.CA…). Today, the first clinical data for a KRAS/PRMT5 combination was reported, with an incredible 92% ORR. RAS inhibitors are the present, but combinations are the future!! $TNGX $RVMD
Happy to have contributed to this new work from @KathleenMulvan4 and @TheSellersLab, showing that KRAS and PRMT5 inhibitors synergy, out now in Cancer Research. KRAS/PRMT5 combos ($RVMD/$TNGX) are now in clinical trials, and results couldn't come sooner! doi.org/10.1158/0008-5472.CA…
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Shaalan Beg MD MBA FASCO retweeted
Pancreatic cancer is finally seeing real hope with KRAS inhibitors, neoantigen vaccines, and AI-powered early detection. These advances are game-changing. Grateful to the entire team for breaking it down so clearly. @realbowtiedoc @cancerassassin1 @ShaalanBeg @ShrutiPatelMD #PancreaticCancer #Oncology #OncTwitter
Pancreatic cancer will look very different in 5 years ✅ KRAS is no longer "undruggable" ✅ Neoantigen vaccines may stop recurrence ✅ AI can identify 'occult' tumors from routine scans We tackle these stories in our new episode! #onlyoncologistsinthebuilding
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Shaalan Beg MD MBA FASCO retweeted
Speak it!
Replying to @BlayneyDouglas
Sadly it is not IRB approvals anymore @BlayneyDouglas NCI sponsored studies use central IRB, pre-approved budget, no contract and they still take 4 months to activate. Hospital and ancillary service reviews need to be simplified
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Shaalan Beg MD MBA FASCO retweeted
There are so many podcasts so why tune in to this one? 1. If you are loking for broad coverage of topics in medicine… 2. Looking for multiple expert perspectives…. 3. Looking for 3 hosts with great chemistry… 4. Want to learn something new…. Then this is it!
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Shaalan Beg MD MBA FASCO retweeted
Agree with Dr. Beg here. Trial activation is too slow and too selective. There is also patient harm from cumulative addition of each step added with the intent to protect patients and investigators. Why not one central, responsive IRB?
Imagine this: If CROs and academic centers would allow clinical trials activation and enrollment in the US to be modernized, the KRAS plenary would have been presented in #asco25 and we would have three more RAS trial readouts by today.

ALT prove me wrong gordon ramsay GIF by MasterChef Junior

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Pancreatic cancer will look very different in 5 years ✅ KRAS is no longer "undruggable" ✅ Neoantigen vaccines may stop recurrence ✅ AI can identify 'occult' tumors from routine scans We tackle these stories in our new episode! #onlyoncologistsinthebuilding
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Shaalan Beg MD MBA FASCO retweeted
Replying to @ShaalanBeg
This tweet was from 4 years ago! So many patient years wasted due to bureaucratic delays in trial enrollment.
KRAS space is buzzing
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