Director of the Systems Immunology Lab @NeckerINEM @Univ_Paris @CNRS. Dissecting virus-host interactions and revealing cell circuits controlling innate immunity
Joined August 2019
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Pinned Tweet
31 Dec 2021
Goodbye NYC, bonjour Paris. After 10 years at Columbia University, a very exciting change on both a personal and professional level. NYC will always have a dear place in my ❤️ as do colleagues who I will surely miss, but boy am I excited for what’s ahead!
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21 Mar 2022
This is so frickin good! Creative on all levels from beginning to end
20 Mar 2022
Wait... What!? Plants with Huntington's disease??? We introduced the toxic fragment of the mutant Huntingtin protein in Arabidopsis plants. (1/12) biorxiv.org/content/10.1101/…
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Sagi Shapira retweeted
11 Jan 2022
@NeckerInem is delighted to welcome Dr. Nicolas Venteclef @VenteclefNicol1, an internationally renowned expert in immunometabolism working on macrophages and type 2 diabetes, as new Group Leader, bringing considerable strength to our fundamental and translational activities.
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6 Sep 2021
You know I’m huge fan, but this is truly inspired!
6 Sep 2021
There's still lots to learn about chromatin complexity due to diversification of histone genes. A phylogenomic analysis of histone H2B genes led by @PravruthaRaman discovers 2 novel histones in mammals (incl humans), one of which is >400 million years old! biorxiv.org/content/10.1101/…
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25 Aug 2021
I really enjoyed reading these two papers from the labs of @jkagan1 and @ClareBryant13. Congratulations to everyone involved! Folks interested in innate immunity, synthetic biology, evolution, or just good science, these are sure to become classics. immunology.sciencemag.org/co…
Here it finally is Jon cell.com/cell-reports/fullte…
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6 Aug 2021
Niiiiice!
5 Aug 2021
Well, this has been a long-awaited day- the first paper on our multicellularity Long Term Evolution Experiment (LTEE) is on the BioRxiv. Ever wonder how simple multicellular organisms evolve to become larger and more complex over thousands of gens? 1/35
biorxiv.org/content/10.1101/…
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12 Jan 2021
Delighted to be kicking off the 2021 QBI Seminar series. This'll be fun!!
Join us on January 27 at 11 AM PT for the first online #QBIseminar of the year featuring Sagi Shapira @ShapiraLab, hosted by Nevan Krogan @KroganLab!
Find out more and register: qbi.ucsf.edu/seminar-shapira
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Sagi Shapira retweeted
11 Jan 2021
That we only vaccinated 292,552 Americans today, having been able to hit 800,000 Thursday (7 Jan), speaks to the lack of any 24/7 plan or ability to execute.
Emergencies don't take off weekends.
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Sagi Shapira retweeted
21 Dec 2020
I’m all for SciComm, but the explosion of discussion on Twitter about virus evolution and viral variants has devolved into a complete shit show, largely because of non-experts with blue checkmarks & large followings tweeting/publishing hyperbolic speculations. Needs to stop!
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For anyone who missed this paper, @gorkalasso BarryHonig & @ShapiraLab use protein structure similarity to scan for molecular mimicry between host & viral proteins. Several interesting candidates identified in pox, herpes, paramyxo, and coronaviruses. doi.org/10.1016/j.cels.2020.…
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26 Nov 2020
More awesome work from @mason_lab. Modern technology meets Jules Vern. Seriously, who wouldn’t find this super cool!? Beam me up Scotty.
25 Nov 2020
Today we're elated to release a set of 30 papers on aerospace medicine and the biology of spaceflight; they are simultaneously featured on the covers of @CellCellPress, @CellReports, & @iScience_CP using photos taken by @StationCDRKelly while in space: cell.com/c/the-biology-of-sp… /1
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16 Nov 2020
At what point does blatant endangerment of human health, promotion of crackpot science, and willful obstruction of efforts to limit future deaths fall under crimes against humanity? @IntlCrimCourt @HagueInstitute
16 Nov 2020
When the WH was asked this morning why they weren’t sharing Covid response info with the Biden team their answer was why should we. Not disputing Biden won, just saying they were under no obligation to help them. Let that sink in.
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7 Nov 2020
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7 Nov 2020
👏👏👏👏👏👏👏
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Sagi Shapira retweeted
7 Nov 2020
So proud of you. ❤️❤️🇺🇸🇺🇸
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Sagi Shapira retweeted
6 Nov 2020
And here it is, your Moment of Zen
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Sagi Shapira retweeted
27 Oct 2020
Coronaviruses are masters of #mimicry, new study finds @ColumbiaMed @NatureMedicine phys.org/news/2020-10-corona…
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Sagi Shapira retweeted
14 Oct 2020
Viruses frequently mimic host proteins (e.g. due to horizontal gene transfer). This paper uses protein structure similarity to scan for mimicry, and points to mimicry as a pervasive strategy employed by viruses.
cell.com/cell-systems/fullte…
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