Cryo-EM aficionado that used tomography and subtomogram averaging to close the gap between HIV cores and Christmas trees.
Joined October 2017
- Tweets 359
- Following 486
- Followers 1,245
- Likes 1,061
21 Photos and videos
Pinned Tweet
9 Oct 2023
Upside down! Our latest in situ cryo-ET work shows how cytosolic ribosomes bind mitochondria via their SSU as an adaptive response to cellular stress. A great collaboration with @jomaa_lab! #TeamTomo @embl @EmblImaging
biorxiv.org/content/10.1101/…
9 Oct 2023
Want to know what happens when mitochondria get stressed? Check our latest pre-print with @SimoneMattei19 lab on how mitochondria tether hibernating ribosomes as an adaptive response to glucose depletion in yeast!
biorxiv.org/content/10.1101/…
#teamtomo #cryoEM #ribosomes #mitochondria
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Simone Mattei retweeted
May 13
Excited to share our work uncovering SNOR, a ribosome-associated factor that promotes translation restart after dormancy published in Nature!! This was, as usual, a wonderful collaborative effort between our group @UVA and @simonemattei @EMBLHeidelberg
nature.com/articles/s41586-0…
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Despite its name, SNOR, a newly discovered protein, is hardly asleep on the job.
EMBL researchers’ newest technologies allowed them to discover this tiny protein with a big role that awakens cells from dormancy to restart protein synthesis.
embl.org/news/science-techno…
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Simone Mattei retweeted
1 Aug 2025
Check out our new preprint on the discovery of a molecular switch in NAC that mediates nascent chain sorting on the ribosome and prevents mitochondrial protein mistargeting by SRP. A great collaboration with the Shan Lab @Caltech and the Qi Lab @UVA: biorxiv.org/content/10.1101/…
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23 Jul 2025
Grateful to the Boehringer Ingelheim Stiftung for their renewed support. Their commitment empowers us to further advance our mission: enabling broad access to state-of-the-art imaging technologies for the scientific community
Boehringer Ingelheim Stiftung has committed €7 million to EMBL’s Imaging Centre.
That means more opportunities to create groundbreaking, next-gen imaging technologies & provide necessary support to European life scientists.
embl.org/news/connections/ne…
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Simone Mattei retweeted
16 Jun 2025
Check out our latest preprint with Qi lab on the structure and disease physiology of the human ERAD complex. Outstanding work by Leo, a cell physiologist whom we successfully tempted into structural biology! Preprint: biorxiv.org/content/10.1101/…
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18 Feb 2025
Thanks to @instructhub funding the @EmblImaging Centre is able to offer an advanced hands-on workshop on cryo-FIB-SEM methods. This is a great opportunity to exchange knowledge with our fantastic cryo-CLEM specialists! Apply here before May 12th: embl.org/about/info/imaging-…
18 Feb 2025
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📣 Apply now: @instructhub INSTRUCT-ERIC hands-on #workshop: Advanced cryo-FIB-SEM methods on 21-25 July 2025. Limited to 12 participants. Apply before 12th May 2025.
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The @ChanZuckerberg Initiative is funding two EMBL projects, coordinated by @EmblImaging, to support imaging technologies development. 🔬
The projects will integrate advanced microscopy techniques to improve the understanding of biological systems.
embl.org/news/science-techno…
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Science meets art at the EMBL Imaging Centre! 🔬🎨
Several scientists shared their experience as users of this facility and explain why it is a unique place to turn your research into stunning, informative images.
Read the full article here 👉 embl.org/news/connections/fr…
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Simone Mattei retweeted
9 Oct 2024
Niels Weidemann edited a volume of Methods in Enzymology on mitochondrial import. I was honoured to write a review about yeast genetics together with Maya Schuldiner! I hope it will be useful.
doi.org/10.1016/bs.mie.2024.…
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8 Oct 2024
It’s great to see our hibernating ribosomes story finally out @NatureComms! Thanks to @jomaa_lab @MedicineUVA and all @EMBL and @EmblImaging people that supported this project. rdcu.be/dWnv6
8 Oct 2024
Happy to share our little discovery with @SimoneMattei19 team on how ribosomes hibernate upside down on mitochondria during cellular stress is now out @NatureComms! A collaboration between @medicineUVA, @EMBL, @EmblImaging, MEMC. Congrats to all authors! nature.com/articles/s41467-0…
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Simone Mattei retweeted
20 Sep 2024
What if we could peer inside a living organism watch biology unfold in real-time...down to the microscopic level? 🔬 Researchers like @Prevedel_Lab are working to make this ultra-high res deep tissue imaging possible!
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6 Sep 2024
Fantastic news! All the best for this scientific journey Yura!
6 Sep 2024
I am very honored to get the @ERC_Research StG and looking forward to the next 5 years of exciting research. I am grateful to my mentors and colleagues who helped me along the way!
rptu.de/en/newsroom/neuigkei…
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Simone Mattei retweeted
5 Sep 2024
Registration now to the @EMBL Imaging Centre User Symposium 2024!
Don't miss this opportunity, especially:
✅ limited workshop by @LeicaMicro and @zeiss_micro
✅ 10 speakers from different expertises
More info & registration: embl.org/about/info/imaging-…
#ImagingTechnology
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Simone Mattei retweeted
8 Aug 2024
How do karyotypes evolve? Turns out an intracellular tug of war within the metaphase spindle sets the limits for chromosome number evolution. Excited to see our study out today in @NatureCellBio nature.com/articles/s41556-0… 1/9
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Simone Mattei retweeted
8 Aug 2024
This is the one 👇🏻
8 Aug 2024
#EMBOCLEM is back and open for applications! 🌟 Learn all about in situ correlative light and electron microscopy while networking and interacting with the experts in the field 🔬 🥼
Course modules include:
🔸 High pressure freezing
🔸 Freeze substitution
🔸 Plunge freezing and micropatterning
...and more!
💻 s.embl.org/lem25-01
⏰ Apply by 17 Nov
🌍 EMBL Heidelberg
📅 9 – 14 Feb
Be sure to apply soon, as this course is in high demand. We hope to see you in February! 🙌
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Simone Mattei retweeted
15 Jul 2024
We are looking for an experienced light microscopy specialist to support the Advanced Light Microscopy Facility @embl Heidelberg: embl.org/jobs/position/HD026… - closing date 5 August 2024
@EuLiMI1 @EuroBioImaging @GerBI_GMB @Fr_BioImaging @GlobalBioImage @BioImagingUK
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Simone Mattei retweeted
8 Jul 2024
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Don’t miss the opportunity to join us at the @EMBL Imaging Centre User Symposium 2024 will be held on 17 to 18 October 2024. Do not miss the deadlines and secure the limited spot. #imaging #CryoEM #superresolution #microscopy.
Read more®ister: shorturl.at/B3FeB
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22 Jun 2024
This is a great opportunity! 👇🏻
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Simone Mattei retweeted
11 Jun 2024
We start the second day of @iNEXT_Discovery final meeting with a talk from one of @instructhub facility @EMBLGrenoble
#EasyGrid a versatile platform from #cryoEM sample preparation developed by @PappTeam in collaboration with @EMBLHeidelberg @SimoneMattei19
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Simone Mattei retweeted
10 May 2024
We have two open PhD positions to explore structures of ribosomes and gamma-tubulin complexes using cryo-EM approaches here in our group @ZmbhH @UniHeidelberg.
Please apply via the Heidelberg Biosciences International Graduate School @HBIGS_HD: hbigs.uni-heidelberg.de/
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