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Stainier Lab @StainierLab

Our lab studies #development #regeneration #geneticrobustness @mpi_hlr. The account is run by various lab members.

Joined March 2022
  • Tweets 177
  • Following 87
  • Followers 1,964
23 Photos and videos
Congratulations to Samuel Capon and coauthors on their latest study that dives into the fascinating world of phenotypic variation in Fibronectin mutants, exploring why the exact same mutation leads to different viability during embryonic development ! 🥳🎉 journals.plos.org/plosgeneti…

A genetic modifier links integrin α5 to the phenotypic variation in fibronectin 1a mutant zebrafish

Author summary Recent studies have identified apparently healthy individuals with mutations that would be expected to lead to disease. Why these individuals are disease resistant is not understood....

journals.plos.org
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Congratulations to the team! 🎉
Christopher Dooley@CMDooley77
23 Jun 2025
Huge thanks to @ACHSEeV, the Köhler Foundation, and our brilliant team @StainierLab @MPI_HLR. Science is a team effort, and this award recognizes that shared dedication. More here 👉 mpi-hlr.de/391963/news_publi… #RareDisease #EvaLuiseKöhler #Duchenne #DMD #TranscriptionalAdaptation
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Stainier Lab retweeted
Paolo Panza@paolo_panza
16 Apr 2025
Grateful for the chance to talk with Janet Rossant and @MingxiaGu ! In this @stemcellreports podcast episode we touch on the roles of the #vasculature in the #lung and I talk a bit about what comes next! @jlugiessen @HeroldLab @CPI_ExStra @StainierLab
StemCellReports@stemcellreports
20 Mar 2025
The newest podcast is now live. Listen here tinyurl.com/ej429twb or wherever you download your favorite podcast. @ISSCR @paolo_panza @StainierLab @MingxiaGu @UCLAstemcell
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Paper alert! Congratulations to all coauthors 🥳👏
Christopher Dooley@CMDooley77
24 Mar 2025
🧵Excited to share our new paper on transcriptional adaptation and the role of RNA destabilization in triggering a TA-like response. Read the full study here 👉 embopress.org/doi/full/10.10… [1/6]
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Congratulations to @TJ_ThomasJuan and all the coauthors! 🎉
Thomas Juan@TJ_ThomasJuan
28 Feb 2025
Very proud to share my latest research on a novel biotechnological tool: The first use of a self-cleaving ribozyme to knock down an endogenous gene in a vertebrate model. Thanks to the @StainierLab and to my co-authors #PLOSGenetics: dx.plos.org/10.1371/journal.…
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Paper alert! Congrats to Lara, @CMDooley77, @DouglasAdamoski and @TJ_ThomasJuan for their great work on identifying the first example of Transcriptional Adaption in humans!🎉
Christopher Dooley@CMDooley77
12 Feb 2025
Replying to @CMDooley77
5/5 🌟 Why It Matters: First evidence of TA in humans! This work rethinks DMD treatment, showing mRNA decay itself can drive genetic compensation. Kudos to 1st Lara! @DouglasAdamoski @TJ_ThomasJuan & team! @MPI_HLR 🎉 #RareDisease
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Stainier lab alumni, register now! 30th anniversary celebration of the Stainier lab from Sunday to Tuesday, 6-8 April 2025 in Bad Nauheim.
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We are happy to announce that we are expanding our social media outreach! 🎉 You can now find us on: Linkedin: linkedin.com/in/stainier-lab… Bluesky: bsky.app/profile/stainierlab…
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Well done! 🎉
Brian Juvik@BrianJuvik
9 Jan 2025
Excited to share this article, where we highlight the possibility that dysregulation of genes via transcriptional adaptation, an mRNA feedback loop, may play a role in some dominant diseases. @StainierLab A new hypothesis to explain disease dominance sciencedirect.com/science/ar…
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Congratulations to Brian, Lara and coauthors on this article highlighting how dysregulation of genes via transcriptional adaptation may play a role in dominant diseases! 🧬🥳🎊 Check out the article here: authors.elsevier.com/sd/arti… sciencedirect.com/science/ar…

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Marco Tarasco@marco_tarasco
11 Dec 2024
PhD Position Alert: Are you interested in studying cardiac fibrosis using the zebrafish as a model? We are looking for a passionate and dedicated PhD student! Find out how to apply below or share this post!! mpg.de/23855570/ph2

Job Offers - Jobboard

Job offers of the Max Planck Society and Institutes. You can combine the "jobtype" with either "research subjects" or "region". Confirm your choice with OK.

mpg.de
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Paper alert! 🥳 Congratulations to @Yanli_Xu_ and all coauthors for their fantastic work on the effectors of HAND2 during early cardiac development. 🎊
Yanli Xu@Yanli_Xu_
10 Dec 2024
Thrilled to share my PhD work published in @NatureCVR ! This journey was challenging, but persistence and dedication truly paid off. A huge thank you to all my co-authors for their support, and especially to my supervisor, Didier Stainier (@StainierLab ), for his guidance!
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Congratulations to all the authors! 🎊
Development@Dev_journal
10 Dec 2024
flt1 inactivation promotes zebrafish cardiac regeneration by enhancing endothelial activity and limiting the fibrotic response Read this #OpenAccess Research Article by Zhen-Yu Wang, @rmarinjuez and colleagues: journals.biologists.com/dev/…
Figure 1 (A-B″) Whole-mount images of cryoinjured ventricles from Tg(-0.8flt1:RFP);flt1 / (n=6, A) and Tg(-0.8flt1:RFP);flt1−/− (n=6, A′) zebrafish, and from Tg(-0.8flt1:RFP) (Ctrl, n=7, B) and Tg(-0.8flt1:RFP);Tg(hsp70l:sflt1) (n=7, B′) zebrafish showing revascularization of the injured area at 96 hpci (A,A′) and 7 dpci (B,B′), and the corresponding percentage of coronary coverage of the injured area (A″,B″)

ALT Figure 1 (A-B″) Whole-mount images of cryoinjured ventricles from Tg(-0.8flt1:RFP);flt1 / (n=6, A) and Tg(-0.8flt1:RFP);flt1−/− (n=6, A′) zebrafish, and from Tg(-0.8flt1:RFP) (Ctrl, n=7, B) and Tg(-0.8flt1:RFP);Tg(hsp70l:sflt1) (n=7, B′) zebrafish showing revascularization of the injured area at 96 hpci (A,A′) and 7 dpci (B,B′), and the corresponding percentage of coronary coverage of the injured area (A″,B″)

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Stainier Lab retweeted
Marco Tarasco@marco_tarasco
5 Dec 2024
📢BIG NEWS! I am thrilled to announce that Novo Nordisk Foundation has awarded us a grant for a 4-year collaboration between @prlunde, @StainierLab , and @AliciaLundby! Together, we'll be studying cardiac fibrosis using #zebrafish as a model! Looking forward to it all!
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Stainier Lab retweeted
Carol Yang@YHCarolYang
27 Nov 2024
The Yang lab will be expanding with MRC & Wellcome funding support! Watch out for recuitment adverts for technician, postdoc & PhD posts over the coming year. If you are interested in neural-pancreas interations, reach out for informal chats. #zebrafish #islet #diabetes
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Congratulations, @BellecMae ! 🎊👏
Maëlle Bellec@BellecMae
27 Sep 2024
And our embryo is on the cover 😍
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Stainier Lab retweeted
Pinelopi Goumenaki@PinelopiGoum
23 Sep 2024
Excited to see our paper @StainierLab "The innate immune regulator MyD88 dampens fibrosis during zebrafish heart regeneration" being highlighted with a News & Views article! Thank you @NatureCVR and Kazu Kikuchi! 😊 nature.com/articles/s44161-0…
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Amazing presentation by @marco_tarasco at ICDAR 2024 on atrial arrhythmia and fibrosis!🎉
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Congratulations to @radha_kul for a fantastic presentation on epicardial-myocardial interactions during early cardiac development! Well done👏🥳 #ICDAR2024
Radha Kulkarni@radha_kul
20 Sep 2024
Grateful to all ICDAR 2024 organizers for giving me this great opportunity to present my work! 🎉 Also a big shoutout to @StainierLab members for their constant support!
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Great talk by @rupal_gehlot at the ICDAR 2024 meeting on the role of hand2 in cardiac valve formation!👏🎉
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