MD, PhD candidate HPB Surgery Amsterdam UMC 🇳🇱| Former Research Fellow Karolinska University Hospital 🇸🇪 & University of Colorado 🇺🇸

Joined June 2022
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Published in @TheLancet, our review on #PancreaticCancer 📎Epidemiology🌎 📎Pathogenesis🔬 📎Risk factors & surveillance🕵️ 📎Diagnostics🩺 📎Treatment💊 📎Future directions🔍 … by @ammar_asrar, @ObaAtsushi, T. Seufferlein, JW Wilmink, @BasGrootKoerkam & @MarcBesselink
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Neurogenic diarrhoea after superior mesenteric artery divestment or resection for pancreatic adenocarcinoma following preoperative chemotherapy: international multicentre retrospective study ➡️doi.org/10.1093/bjsopen/zrag… In this international multicentre study including 291 patients with superior mesenteric artery (SMA) divestment/resection during surgery for pancreatic adenocarcinoma after preoperative chemotherapy, postoperative neurogenic diarrhoea occurred in 66% of patients, particularly after > 180° SMA divestment or resection. Although challenging to manage, neurogenic diarrhoea was not associated with impaired survival. 👏👏👏@TFStoop , Chiara Croce , Hiroyuki Ishida , Mahsoem Ali , Ammar A Javed , Asif Halimi , Atsushi Oba , Bas Groot Koerkamp , Carl-Stephan Leonhardt , Cornelius A Thiels , Elena Rangelova , Ernesto Sparrelid , Ira Sotirova , Jennifer L Leiting , Jun Tauchi , Kosuke Kobayashi , Marit Klos , Lysanne P M Beuk , Luana Genova , Manuela Mastronardi , Michael L Kendrick , Nabiha A Mughal , Olivier R Busch , Oskar Franklin , Patrik Larsson , Ulla Klaiber , Richard D Schulick , Rutger T Theijse , Oliver Strobel , Poya Ghorbani , Roeland F de Wilde , Salvador Rodriguez Franco , Toshitaka Sugawara , Johanna W Wilmink , Wells Messersmith , @MarcBesselink , Christopher Wolfgang , Yosuke Inoue , Mark J Truty , @chiaro_del on behalf of the , International Collaboration on Advanced Pancreatic Cancer #SoMe4Surgery #MedTwitter #SurgEd #Surgery @BJSAcademy @BJSurgery #some4hpb #some4tpl @hpb_so #PancreaticCancer #PancreaticSurgery @YouppiePancreas @German_PancClub @surgery_hps #PancreasClub2023 @PancreasClub @DPCG_official @pancreatitis_nl @PanCAN #PanCANawareness @EurPancClub @P_C_E_ @dice_europe
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In @BjsOpen, study 🇳🇱🇩🇪🇸🇪🇺🇸🇮🇹 on surgery risks in #pancreascancer #LAPC after preop RTx ☢️: ⬆️ major morb after RT (38% vs 24%) 📎especially if arterial resection 📎especially if EBRT 🖇️no significant association of RT with PPH 🩸 (11% vs. 5%) 🚨selection & counselling
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In @BjsOpen, study 🇳🇱🇦🇹🇺🇸🇯🇵🇸🇪 on #neurogenic #diarrhea after #pancreaticcancer surgery with SMA divestment/resection: 📎66% rate, mostly if >180° SMA divestment/resection 🚨large treatment heterogeneity ➡️ 51% normalized 👍 no ⬇️ OS 🔎definition & evidence-based strategies⚠️
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Original Article: Daraxonrasib or Chemotherapy in Previously Treated Metastatic Pancreatic Cancer (phase 3 RASolute 302 trial) nej.md/4nWaxvM #ASCO26 | @ASCO
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#HoraEst 🎓 @IngmarFRompen today @UvA_Amsterdam “Extended indications for #pancreatic #surgery (#promotie). Well done Ingmar!! ➡️ dare.uva.nl/id/9c78faf9-53e8… 🎯Amazing thesis including 14 chapters, all published, including 9x(!!) @AnnalsofSurgery. Thanks to all 99 co-authors from 🇩🇪🇺🇸🇳🇱 🇮🇹🇳🇴🇸🇪🇫🇮🇩🇰🇬🇧🇯🇵 ✅ Wonderful collaborative PhD team @MarcBesselink @cw_michalski 🇩🇪 @cwolfga2 🇺🇸 @ammar_asrar 🇺🇸 @DPCG_official Thanks to the excellent committee including @Gio_Marchegiani @TFStoop @i_verpalen @HenrikNien
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#PELICAN randomized trial @DPCG_official 🇳🇱 published @JAMANetworkOpen: ❓Can #RFA following induction chemoth improve survival vs chemoth only in 188 pts with nonprogressive but nonoperable locally advanced #pancreaticcancer (#LAPC)? 🔑 No. Moreover QoL ⤵️ 👀 #PREOPANC4 coming up. ▶️ jamanetwork.com/journals/jam…
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#Horaest 🎓 @TFStoop #CumLaude PhD ceremony today 🙌 (best 3% thesis) “A #paradigm #shift in localized #PancreaticCancer@DPCG_official, @UvA_Amsterdam ⏩️ dare.uva.nl/search?identifie…#PREOPANC4 nationwide 🇳🇱 implementation LAPC surgery ✅International, national studies on #neoadjuvant #adjuvant treatment #quality of life and #surgery in #PancreaticCancer ✅543 pages, 19 chapters (incl @TheLancet), 150 co-authors, 20 countries, 286 impact factor points; median 10 . Thank you @sparrelid🇸🇪 for the excellent discussion!
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Proud to have Dr.Oba in our Division! Dive into the story below.
Read all about it! Japanese Surgeon Atsushi Oba, MD, PhD, Joins Pancreatic Program At CU Anschutz Department of Surgery. @ObaAtsushi @CUpancreas @CUDeptSurg #ImproveEveryLife news.cuanschutz.edu/departme…
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Bihormonal Artificial Pancreas after #Total #Pancreatectomy? ✅Protocol #PANORAMA trial published @BjsOpen @DPCG_official 🇳🇱 >> results coming up…. ⏩️ academic.oup.com/bjsopen/art…
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We extend our sincerest gratitude to Dr. Schulick for his exceptional service as Chair of the @CUDeptSurg, during which he guided significant growth and innovation. His vision and dedication leave an extraordinary impact. #ImproveEveryLife @RichSchulickMD @chiaro_del
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#HoraEst today for @annegehrels om #PancreaticCancer with @DPCG_official 🇳🇱 @UvA_Amsterdam ⏩️ hdl.handle.net/11245.1/0af5e…#NAPAN trial: Second-line liposomal irinotecan plus S-1 vs. liposomal irinotecan plus 5-fluorouracil in metastatic pancreatic cancer: the phase I/II randomized trial ✅#PREOPANC5 trial protocol: Neoadjuvant mFOLFIRINOX, pembro, and SBRT for borderl resect pancreatic cancer: multicenter phase 1/2 single-arm trial Excellent multidisciplinary collaboration Hanneke Wilmink, Hanneke van Laarhoven an in the committe Davide Melisi 🇮🇹
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#HoraEst today for @MichielFrancken @amsterdamumc @UvA_Amsterdam “Interventions for pancreatic diseases” ✅ #POINTER trial costs ✅#PICUS2 cholecystectomy for idiopathic pancreatitis, trial design ✅#PANACOTTA (obot vs open PJ chronic pancreatitis, trial design Incl committee @DeMadaria 🇪🇸 gracias Enrique🙌 dare.uva.nl/search?field1=ke…
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The evidence would support performing diag laparoscopy prior to #NAT💊 and surgery✂️ 22% detection rate of occult metastases on🥢 in upfront resection pts in modern series with high quality imaging 🖥️ at experienced center @PanCAN @SocSurgOnc @IHPBA pmc.ncbi.nlm.nih.gov/article…
Staging laparoscopy 🙈 waste of time or added value!? 🗣️ 617 Surgeons / 76 countries ⏱️ Mostly performed same session laparotomy 🧐 Useful in suspicious radiology / ⬆️ CA 19.9 👉 Does not hurt increase staging accuracy hpbonline.org/article/S1365-…
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The Division of Surgical Oncology is thrilled to welcome Atsushi Oba, MD, PhD as Associate Professor of Surgery at the University of Colorado Anschutz Medical Campus! @CUpancreas @CUDeptSurg @ObaAtsushi #ImproveEveryLife
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Staging laparoscopy 🙈 waste of time or added value!? 🗣️ 617 Surgeons / 76 countries ⏱️ Mostly performed same session laparotomy 🧐 Useful in suspicious radiology / ⬆️ CA 19.9 👉 Does not hurt increase staging accuracy hpbonline.org/article/S1365-…
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