Neuroscientist. Interested in neural coding, computational methods, retinal physiology, and vision. Working at the University Medical Center Göttingen.
65 years after Lettvin’s bug detector neurons in the frog retina, we revisit how the retina drives behavior—from reflexes to prey capture to brain-state modulation
New review with @AnnaIntegrated & Serena Riccitelli in Annual Review of Vision Science 👇
tinyurl.com/ymp3vs4d
New preprint! 🔥A wonderful collaboration of our @FellerMarla lab with Matthew Po, and @shekharlab. Here, we dive into the impact of activity on the transcriptome of retinal ganglion cells (RGCs), the sole output neurons of the retina. 1/12
biorxiv.org/content/10.1101/…
We have a new PhD position available. Please spread the word and retweet. The project will combine retina recordings, computational modeling, and optogenetics to help further develop vision restoration therapy. See here for more information: retina.uni-goettingen.de/joi…
A very warm welcome to Oliver Barnstedt (@obarnstedt) joining @MBExC_de and @yourUMG as junior research group leader for "Multiscale Circuit Analysis".
Have a great start!
Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it🔬🧠🦠🧵👇@cellhostmicrobecell.com/cell-host-microbe/f…
How natural stimuli lead to highly correlated ganglion cell activity in primate (marmoset) and mouse retina. Now out in @nature.
nature.com/articles/s41586-0…
Thanks so much to Dimos Karamanlis for spearheading this, and thanks for a great team effort and for the funding support! @yourUMG@ERC_Research@dfg_public
🚨New preprint from the lab!🚨
We found a preference for visual objects in the mouse spatial navigation system and discovered that visual objects dynamically boost the encoding of head-direction!
biorxiv.org/content/10.1101/…
🧵👇1/
🥳Super pumped to share our latest collaboration with @EmilieMaceLab and Stuart Trenholm.
We show how visual objects specifically recruit neurons in the spatial navigation system, especially in the head-direction network, suggesting a specific circuit to detect landmarks 1/
Research led by @yourUMG, working with international colleagues and our Uni, has developed a new method making it possible for the first time to image the 3D shape of proteins with a conventional microscope: ONE microscopy - for One-step Nanoscale Expansion microscopy.
ONE microscopy not only allows 3D reconstructions of protein molecules but also reveals details in GABAA receptors that X-ray crystallography and cryo-EM missed, yet AlphaFold predicted. More here:
nature.com/articles/s41587-0…@NatureBiotech.
Our GABAA receptor work owes everything to the support of cryo-EM leading expert Prof. @RaduAricescu and his lab at MRC, UK. Thank you!