This account is run by Olga Troyanskaya and her group focusing on computational functional genomics at Princeton University.

Joined August 2011
2 Photos and videos
Troyanskaya Lab retweeted
12 Jul 2022
The Sei web server on humanbase (hb.flatironinstitute.org/sei) is now updated to add the capability of computing Sei predictions including sequence class scores for any user-provided sequences or variants (big thanks to @wongak!)

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Troyanskaya Lab retweeted
Machine learning in materials science! All our articles on machine learning in one collection, featuring @EKumachevaGroup @A_Aspuru_Guzik @TroyanskayaLab @draykol @SmitBerend @GormleyLab @xmwebb @NAresgroup @MKrallinger and many more - Check it out 😎go.nature.com/3gdwuVw
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Troyanskaya Lab retweeted
Our new preprint (w/ @zhou_jian) is out! 🎉 We developed sequence classes, which allow for easily interpretable yet systematic quantification of the regulatory activities for any sequence & variant, using deep learning-based sequence modeling. (1/13) doi.org/10.1101/2021.07.29.4…

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Check out our latest review in NRG on decoding disease - from genomes to networks to phenotypes! nature.com/articles/s41576-0…

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Check out our review of machine learning methods to model multicellular complexity!
High-throughput experiments generate large data sets that allow the study of multicellular complexity; #MachineLearning can help analyse, interpret and model these datasets. Read more in the Review by Rachel Sealfon, @wongak & @OlgaTroyanskaya: go.nature.com/3hJ0ucT
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Troyanskaya Lab retweeted
High-throughput experiments generate large data sets that allow the study of multicellular complexity; #MachineLearning can help analyse, interpret and model these datasets. Read more in the Review by Rachel Sealfon, @wongak & @OlgaTroyanskaya: go.nature.com/3hJ0ucT
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Troyanskaya Lab retweeted
Combing through millions of possible protein combinations to assemble a catalog that could be used to precisely target only cancer cells while leaving normal ones alone. Kudos to @limlab @UCSF @OlgaTroyanskaya @TroyanskayaLab ow.ly/QXMh50CylWC
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Troyanskaya Lab retweeted
It's #OlgaFest today in Michigan! 😀 @OlgaTroyanskaya's academic children & grandchildren are speaking in today's @WomenPlusData webinar hosted jointly by @UMich and @michiganstateu!
Excited to host the final webinar of this season: 'Data Science in Biomedical Research' featuring Maria @ChikinaLab as our keynote speaker @PittTweet! ⚡ talks Anna @annakopoulos Kayla @kaylainbio Stephanie @slepphickey @CMSE_at_MSU @KrishnanLab Regstr: forms.gle/nbWrEdPR7fDPcKBy6
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thrilled to be a part of this collaboration and apply our cell-type specific networks at @HumanBaseFI to COVID-19.
SARS-CoV-2 receptor networks in diabetic and COVID-19 associated kidney disease kidney-international.org/art… . @MiKTMC @UMichKidney @umichmedicine @Berthiercc @OlgaTroyanskaya .
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Troyanskaya Lab retweeted
SARS-CoV-2 receptor networks in diabetic kidney disease, BK-Virus nephropathy and COVID-19 associated acute kidney injury medrxiv.org/cgi/content/shor… #medRxiv

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Troyanskaya Lab retweeted
4 Dec 2019
Hi genomics community! I recently started my own group at UTSW. We are looking for postdoc and students interested in machine learning and genomics to join us in our adventures in new frontiers! Please RT or forward to any potential interested candidates zhoulab.io/home#join-us

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Troyanskaya Lab retweeted
Our latest paper on noncoding contributions in #autism using deep learning models is out in @NatureGenet. De novo noncoding variants contribute to # of cases comparable to coding. With @darnelr @zhou_jian @pazpark @chandralt4 @simonsFdn @princeton #WGS rdcu.be/bEAto

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Troyanskaya Lab retweeted
ExPecto predicts tissue-specific expression and variant effect ab initio from sequence, prioritizes all GWAS variants, generates in silico mutagenesis of all TSS proximal regions, and provides a link to evolutionary constraints on gene expression. rdcu.be/233k

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Troyanskaya Lab retweeted
Proud of our discovery of noncoding regulatory signal in autism. Independently confirmed in discovery and replication cohorts for both DNA and RNA regulation. #deeplearning #WGS #autism #ASD biorxiv.org/content/early/20…

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Troyanskaya Lab retweeted
Great talk from @OlgaTroyanskaya on predicting effects of mutations with DeepSEA and now being able to predict tissue specific gene expression with new ExPecto approach. Valuable for GWAS causal variant prioritization and de novo calling of disease variants #T2G18
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Troyanskaya Lab retweeted
CS Prof. Olga Troyanskaya and team presented big-data approaches to drug development at the "Celebrate Princeton Invention" event. @OlgaTroyanskaya princeton.edu/news/2017/11/1…
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